公开(公告)号：WO2016025468A3

公开(公告)日：2016-06-16

申请号：PCT/US2015044638

申请日：2015-08-11

Applicant: UNIV ILLINOIS

Inventor： ROGERS JOHN A ,  KOH AHYEON ,  KANG DAESHIK ,  LIU YUHAO ,  HUANG XIAN

IPC: A61B5/00

CPC classification number: A61B5/6833 ,  A61B5/002 ,  A61B5/0075 ,  A61B5/01 ,  A61B5/053 ,  A61B5/14514 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546

Abstract: Skin-mounted or epidermal devices and methods for monitoring biofluids are disclosed. The devices comprise a functional substrate that is mechanically and/or thermally matched to skin to provide durable adhesion for long-term wear. The functional substrates allow for the microfluidic transport of biofluids from the skin to one or more sensors that measure and/or detect biological parameters, such as rate of biofluid production, biofluid volume, and biomarker concentration. Sensors within the devices may be mechanical, electrical or chemical, with colorimetric indicators being observable by the naked eye or with a portable electronic device (e.g., a smartphone). By monitoring changes in an individual's health state over time, the disclosed devices may provide early indications of abnormal conditions.

Abstract translation: 公开了用于监测生物流体的皮肤安装或表皮装置和方法。 这些装置包括与皮肤机械和/或热匹配的功能基材，以提供长期耐磨的持久粘合。 功能基底允许生物流体从皮肤到测量和/或检测生物参数（例如生物流体产生速率，生物流体体积和生物标志物浓度）的一个或多个传感器的微流体传输。 装置内的传感器可以是机械的，电的或化学的，并且可以通过裸眼或便携式电子装置（例如，智能电话）观察比色指示器。 通过监测个体健康状态随时间的变化，所公开的装置可以提供异常状况的早期指示。

公开(公告)号：CA2957932A1

公开(公告)日：2016-02-18

申请号：CA2957932

申请日：2015-08-11

Applicant: UNIV ILLINOIS

Inventor： ROGERS JOHN A ,  KOH AHYEON ,  KANG DAESHIK ,  LIU YUHAO ,  HUANG XIAN

IPC: A61B5/145

Abstract: Skin-mounted or epidermal devices and methods for monitoring biofluids are disclosed. The devices comprise a functional substrate that is mechanically and/or thermally matched to skin to provide durable adhesion for long-term wear. The functional substrates allow for the microfluidic transport of biofluids from the skin to one or more sensors that measure and/or detect biological parameters, such as rate of biofluid production, biofluid volume, and biomarker concentration. Sensors within the devices may be mechanical, electrical or chemical, with colorimetric indicators being observable by the naked eye or with a portable electronic device (e.g., a smartphone). By monitoring changes in an individual's health state over time, the disclosed devices may provide early indications of abnormal conditions.