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1.发明申请HIGH RESOLUTION GAMMA RAY DETECTORS FOR POSITRON EMISSION TOMOGRAPHY (PET) AND SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT) 审中-公开用于正电子发射断层显像（PET）和单光子发射计算机断层显像（SPECT）的高分辨率伽马射线检测器
公开(公告)号：WO9107673A3
公开(公告)日：1991-06-27
申请号：PCT/US9006571
申请日：1990-11-09
Applicant: UNIV TEXAS , UNIV CALIFORNIA
Inventor： FENYVES ERVIN J , ANTICH PIETRO P , ATAC MUZAFFER , CLINE DAVID B
CPC classification number: G01T1/201 , A61B6/037 , G01T1/2985
Abstract: A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 or 90° to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radiactive isotopes than presently used in typical PET systems.
Abstract translation: 本发明提供了一种用于在诊断成像系统中检测伽马射线的装置和方法，其优选地利用快速阶跃折射率闪烁纤维和光电倍增管。 多个闪烁纤维形成为包括在每层中彼此纵向相互定位的基本上平行的纤维的层。 每层平行于每个相邻层设置，每层具有其各自的纤维，其角度基本上为60°或90°; 到每个相邻的层。 优选地，提供位置灵敏的光电倍增器，并且每个光电倍增器耦合到多个光纤，并且每个光纤具有耦合到光电倍增器的至少一端。 收集并处理来自每个光电倍增管的数据输出，以确定检测到的伽玛射线的起始位置的空间坐标。 本发明提供具有改进的信噪比的高分辨率伽马射线检测器。 这显着改善了目前使用的PET和SPECT系统的诊断能力，并极大地扩展了它们在医学诊断和研究中的应用领域。 此外，本发明能够使用比目前在典型PET系统中使用的寿命更长的正电子发射辐射同位素。
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公开(公告)号：AU6956491A
公开(公告)日：1991-06-13
申请号：AU6956491
申请日：1990-11-09
Applicant: UNIV TEXAS
Inventor： FENYVES ERVIN J , ANTICH PIETRO P , ATAC MUZAFFER , CLINE DAVID B
Abstract: A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 DEG or 90 DEG to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radioactive isotopes than presently used in typical PET systems.
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公开(公告)号：CA2069926A1
公开(公告)日：1991-05-10
申请号：CA2069926
申请日：1990-11-09
Applicant: UNIV TEXAS , UNIV CALIFORNIA
Inventor： FENYVES ERVIN J , ANTICH PIETRO P , ATAC MUZAFFER , CLINE DAVID B
Abstract: 2069926 9107673 PCTABS00005 A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 or 90· to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radiactive isotopes than presently used in typical PET systems.
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Patent Agency Ranking
公开(公告)号：ES2080290T3
公开(公告)日：1996-02-01
申请号：ES91901033
申请日：1990-11-09
Applicant: UNIV TEXAS , UNIV CALIFORNIA
Inventor： FENYVES ERVIN J , ANTICH PIETRO P , ATAC MUZAFFER , CLINE DAVID B
Abstract: A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 DEG or 90 DEG to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radioactive isotopes than presently used in typical PET systems.
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公开(公告)号：DK0500798T3
公开(公告)日：1996-01-02
申请号：DK91901033
申请日：1990-11-09
Applicant: UNIV TEXAS , UNIV CALIFORNIA
Inventor： ANTICH PIETRO P , FENYVES ERVIN J , ATAC MUZAFFER , CLINE DAVID B
Abstract: A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 DEG or 90 DEG to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radioactive isotopes than presently used in typical PET systems.
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公开(公告)号：AT128557T
公开(公告)日：1995-10-15
申请号：AT91901033
申请日：1990-11-09
Applicant: UNIV TEXAS , UNIV CALIFORNIA
Inventor： FENYVES ERVIN J , ANTICH PIETRO P , ATAC MUZAFFER , CLINE DAVID B
Abstract: A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 DEG or 90 DEG to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radioactive isotopes than presently used in typical PET systems.
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公开(公告)号：AU6449994A
公开(公告)日：1994-11-21
申请号：AU6449994
申请日：1994-03-21
Applicant: UNIV TEXAS
Inventor： ANTICH PETER P , ANDERSON JON A , FENYVES ERVIN J
Abstract: Apparatus for generating a high contrast image of a living subject includes an X-ray source capable of generating an X-ray beam having an energy between about 4 MeV and about 40 MeV, means for directing the X-ray beam generated by the X-ray source to a preselected area of the body of a living subject, and at least one scintillating detector capable of detecting photons which are generated as a result of the interaction of the X-ray beam with the body of the living subject.
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公开(公告)号：AU643963B2
公开(公告)日：1993-12-02
申请号：AU6956491
申请日：1990-11-09
Applicant: UNIV TEXAS , UNIV CALIFORNIA
Inventor： FENYVES ERVIN J , ANTICH PIETRO P , ATAC MUZAFFER , CLINE DAVID B
Abstract: A device and method for detecting gamma rays in a diagnostic imaging system preferably utilizing fast step index scintillating fibers and photomultipliers is provided by the present invention. A plurality of scintillating fibers are formed into layers comprising substantially parallel fibers positioned lengthwise each other in each layer. Each layer is positioned parallel each adjacent layer with each layer having its respective fibers at an angle of substantially either 60 DEG or 90 DEG to each adjacent layer. Preferably, position sensitive photomultipliers are provided and each photomultiplier is coupled to a plurality of fibers and each fiber has at least one end coupled to a photomultiplier. Data output from each photomultiplier is collected and processed to determine spatial coordinates of the origination position of a detected gamma ray. The present invention provides a high resolution gamma ray detector having an improved signal-to-noise ratio. This improves significantly the diagnostic power of the presently used PET and SPECT systems, and greatly extends the field of their application both in medical diagnosis and research. In addition, the present invention enables use of longer-lived positron emitting radioactive isotopes than presently used in typical PET systems.
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