公开(公告)号：WO2021243464A1

公开(公告)日：2021-12-09

申请号：PCT/CA2021/050765

申请日：2021-06-03

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： DINIZ DE CARVALHO, Daniel ,  MEHDIPOUR, Parinaz ,  MARHON, Sajid

IPC: C12Q1/6809 ,  A61K45/00 ,  A61P35/00 ,  A61K45/06

Abstract: There is described herein a method of assessing a subject's responsiveness to cancer therapy, comprising: providing a sample from the subject comprising cancers cells or suspected cancer cells; measuring or estimating the expression levels of inverted repeats (IR) Alus in the cells; and determining that the subject would be responsive to 5 cancer therapy if the subject cells exhibit expression levels of inverted repeats (IR) Alus with reference to expression levels in control samples.

公开(公告)号：EP4162070A1

公开(公告)日：2023-04-12

申请号：EP21817052.0

申请日：2021-06-03

Applicant: University Health Network

Inventor： DINIZ DE CARVALHO, Daniel ,  MEHDIPOUR, Parinaz ,  MARHON, Sajid

IPC: C12Q1/6809 ,  A61K45/00 ,  A61P35/00