公开(公告)号：AU8077194A

公开(公告)日：1995-05-08

申请号：AU8077194

申请日：1994-10-21

Applicant: UNIVERSITY OF CONNECTICUT THE

Inventor： SEKELLICK MARGARET J ,  MARCUS PHILIP I ,  FERRANDINO ANTHONY F

IPC: A61K38/00 ,  C07K14/555 ,  C12N15/20 ,  C12N15/21 ,  C12N15/85 ,  C12N15/00 ,  C12P21/02 ,  A61K38/21 ,  A01K67/027 ,  C12N15/11

Abstract: The present invention relates to a chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 1. The present invention also relates to a method of producing biologically active chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fowl having the chicken interferon gene incorporated therein, and method for delivery of the chicken interferon in the bird, such as by genetic immunization or aerosol. Expression of the chicken IFN gene yields functional chicken interferon.