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公开(公告)号:WO2017221075A1
公开(公告)日:2017-12-28
申请号:PCT/IB2017/000959
申请日:2017-06-23
Applicant: UNIVERSITY OF SASKATCHEWAN
Inventor: TIKOO, Suresh, K. , ZHAO, Xin
IPC: C12N15/861 , A61K35/76 , A61K39/00 , A61K48/00 , A61P37/04 , C07K14/075 , C12N15/34 , C12N5/10 , C12N7/01
Abstract: The present application provided defective bovine adenovirus (BAV) vectors that lack pV function. Cell lines and methods of preparing such vectors are provided. In addition, the invention provides methods of treating a disease or disorder with a defective BAV lacking pV function as well as vaccine comprising a defective BAV lacking pV function.
Abstract translation: 本申请提供了缺乏pV功能的缺陷型牛腺病毒(BAV)载体。 提供了细胞系和制备这种载体的方法。 此外,本发明提供了治疗具有缺乏pV功能的缺陷BAV的疾病或病症的方法以及包含缺乏pV功能的缺陷BAV的疫苗。 p>
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公开(公告)号:EP3475435A1
公开(公告)日:2019-05-01
申请号:EP17814828.4
申请日:2017-06-23
Applicant: University of Saskatchewan
Inventor: TIKOO, Suresh, K. , ZHAO, Xin
IPC: C12N15/861 , A61K35/76 , A61K39/00 , A61K48/00 , A61P37/04 , C07K14/075 , C12N15/34 , C12N5/10 , C12N7/01
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