公开(公告)号：US11806676B2

公开(公告)日：2023-11-07

申请号：US17262301

申请日：2019-07-25

Applicant: Universiteit Twente

Inventor： Dimitrios Stamatialis ,  Ilaria Geremia

IPC: B01D69/14 ,  B01D69/02 ,  B01D71/62 ,  B01D71/68 ,  A61M1/34 ,  A61M1/16 ,  B01D71/02 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32

CPC classification number: B01D69/147 ,  A61M1/34 ,  B01D69/02 ,  B01D71/021 ,  B01D71/62 ,  B01D71/68 ,  B01J20/20 ,  B01J20/28026 ,  B01J20/28038 ,  B01J20/28085 ,  B01J20/321 ,  B01J20/324 ,  B01J20/3212 ,  A61M1/1696 ,  B01D2325/36

Abstract: Disclosed are compositions for use in the simultaneous removal of endotoxins from dialysate and uremic solutes from blood during the treatment of patients. The treatment is selected from the group consisting of hemodialysis and hemodiafiltration. The compositions comprise sorbent particles embedded in a membrane comprising a polymer and a hydrophilic additive.

公开(公告)号：US20210252462A1

公开(公告)日：2021-08-19

申请号：US17262301

申请日：2019-07-25

Applicant: Universiteit Twente

Inventor： Dimitrios Stamatialis ,  Ilaria Geremia

IPC: B01D69/14 ,  B01J20/32 ,  B01J20/20 ,  B01J20/28 ,  B01D71/68 ,  B01D71/62 ,  B01D71/02 ,  B01D69/02

Abstract: Disclosed are compositions for use in the simultaneous removal of endotoxins from dialysate and uremic solutes from blood during the treatment of patients. The treatment is selected from the group consisting of hemodialysis and hemodiafiltration. The compositions comprise sorbent particles embedded in a membrane comprising a polymer and a hydrophilic additive.

公开(公告)号：US20220401889A1

公开(公告)日：2022-12-22

申请号：US17776604

申请日：2020-11-20

Applicant: Stichting voor de Technische Wetenschappen ,  UMC Utrecht Holding B.V. ,  Universiteit Utrecht Holding B.V. ,  Universiteit Twente

Inventor： Dimitrios Stamatialis ,  Ilaria Geremia ,  Cornelus Franciscus van Nostrum ,  Karin Gerarda Frederika Gerritsen ,  Robert Smakman ,  Wilhelmus Everhardus Hennink ,  Jacobus Adrianus Wilhelmus Jong ,  Yong Guo

IPC: B01D69/14 ,  B01D71/68 ,  B01J20/28 ,  B01D69/08 ,  B01D69/02 ,  B01D69/06 ,  B01D67/00 ,  B01D71/44

Abstract: The present invention relates to a method for preparing a membrane comprising sorbent particles that bind urea. The invention also relates to the sorbent-comprising membranes per se, and to methods of using the membranes. The membranes are useful for undergoing subsequent reactions with small molecules such as urea, for instance to remove urea from a solution.