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1.发明授权Covalently functionalized nanodiamond-based MALDI matrices and methods of use thereof 有权共价功能化的基于纳米金刚石的MALDI基质及其使用方法公开(公告)号：US09012838B2
公开(公告)日：2015-04-21
申请号：US14257412
申请日：2014-04-21
Applicant: University of Saskatchewan
Inventor： Anas El-Aneed , Jackson Chitanda
IPC: B01D39/02 , B32B5/16 , B05D7/00 , C08F2/46 , C07C59/68 , C07C255/41 , C07C59/52 , H01J49/00 , A61K31/196 , A61K31/4172 , A61K47/48 , A61K48/00 , C12N15/113 , C01B31/06 , B82Y5/00
CPC classification number: C07C59/68 , A61K47/6929 , B82Y5/00 , C01B32/28 , C07B2200/11 , C07C255/41 , C07C2604/00 , H01J49/164 , Y10T428/2982 , Y10T436/143333
Abstract: The present disclosure relates to functionalized nanodiamonds comprising at least one MALDI matrix covalently bonded to a nanodiamond and compositions comprising the same. The present disclosure also relates to methods of performing matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS), for example on small molecules, using matrices comprising at least one MALDI matrix covalently bonded to a nanodiamond.
Abstract translation: 本公开内容涉及包含至少一个共价键合到纳米金刚石的MALDI基质的功能化纳米金刚石和包含其的组合物。 本公开还涉及使用包含至少一个共价键合到纳米金刚石的MALDI基质的基质进行基质辅助激光解吸/电离 - 质谱（MALDI-MS）的方法，例如在小分子上。
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2.发明申请COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF 有权基于共价功能的纳米二基的MALDI矩阵及其使用方法公开(公告)号：US20140312218A1
公开(公告)日：2014-10-23
申请号：US14257412
申请日：2014-04-21
Applicant: University of Saskatchewan
Inventor： Anas El-Aneed , Jackson Chitanda
IPC: C07C59/68 , H01J49/00 , C07C229/26 , C07C255/41 , C07C59/52
CPC classification number: C07C59/68 , A61K47/6929 , B82Y5/00 , C01B32/28 , C07B2200/11 , C07C255/41 , C07C2604/00 , H01J49/164 , Y10T428/2982 , Y10T436/143333
Abstract: The present disclosure relates to functionalized nanodiamonds comprising at least one MALDI matrix covalently bonded to a nanodiamond and compositions comprising the same. The present disclosure also relates to methods of performing matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS), for example on small molecules, using matrices comprising at least one MALDI matrix covalently bonded to a nanodiamond.
Abstract translation: 本公开内容涉及包含至少一个共价键合到纳米金刚石的MALDI基质的功能化纳米金刚石和包含其的组合物。 本公开还涉及使用包含至少一个共价键合到纳米金刚石的MALDI基质的基质进行基质辅助激光解吸/电离 - 质谱（MALDI-MS）的方法，例如在小分子上。
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