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公开(公告)号:US20200062782A1
公开(公告)日:2020-02-27
申请号:US16328250
申请日:2017-09-08
Applicant: University of Saskatchewan
Inventor: Joseph KAKISH , Edward KROL , Jeremy LEE , Kevin ALLEN
IPC: C07D519/00 , A61K51/04 , C07D473/12
Abstract: Bifunctional molecules having first and second alpha-synuclein binding agents coupled by a linker are disclosed. The bifunctional molecules have potential utility in the diagnosis, treatment and/or prophylaxis of disorders in which alpha-synuclein is implicated, including Parkinson's disease. Methods of making and using the bifunctional molecules are disclosed.