公开(公告)号：CA2194485C

公开(公告)日：2001-09-18

申请号：CA2194485

申请日：1996-05-03

Applicant: VASOGEN INC

Inventor： BOLTON ANTHONY ERNEST ,  COOKE ERNEST DAVIDSON

IPC: A61K35/14 ,  A61P7/00 ,  A61K41/00 ,  C12N5/06 ,  C12N5/08

Abstract: Vasospastic disorders such as Raynaud's phenomenon are treated by administering to the patient an aliquot of autologous blood which has been subjected simultaneously to heat, ultraviolet irradiation and oxidative environment so as to render the blood aliquot capable of generating in the patient's bloodstream after administration a population of stimulated leukocytes having upregulated expression of CD25 cell surface markers, along with an enhancement of endothelial function in the patient.

公开(公告)号：AU760465B2

公开(公告)日：2003-05-15

申请号：AU6252100

申请日：2000-10-06

Applicant: VASOGEN INC

Inventor： BOLTON ANTHONY ERNEST ,  COOKE ERNEST DAVIDSON

IPC: A61K35/14 ,  A61K41/00 ,  A61P9/10

公开(公告)号：CA2194485A1

公开(公告)日：1996-11-07

申请号：CA2194485

申请日：1996-05-03

Applicant: VASOGEN INC

Inventor： BOLTON ANTHONY ERNEST ,  COOKE ERNEST DAVIDSON

IPC: A61K35/14 ,  A61P7/00 ,  A61K41/00 ,  C12N5/06 ,  C12N5/08

Abstract: Vasospastic disorders such as Raynaud's phenomenon are treated by administering to the patient an aliquot of autologous blood which has been subjected simultaneously to heat, ultraviolet irradiation and oxidative environment so as to render the blood aliquot capable of generating in the patient's bloodstream after administration a population of stimulated leukocytes having upregulated expression of CD25 cell surface markers, along with an enhancement of endothelial function in the patient.

公开(公告)号：AU721530B2

公开(公告)日：2000-07-06

申请号：AU5494496

申请日：1996-05-03

Applicant: VASOGEN INC

Inventor： BOLTON ANTHONY ERNEST ,  COOKE ERNEST DAVIDSON

IPC: A61K35/14 ,  A61P7/00