System and method for determining cell adequacy in a cytological analysis system

    公开(公告)号:AU2016285895A1

    公开(公告)日:2018-01-18

    申请号:AU2016285895

    申请日:2016-06-27

    Applicant: VISIONGATE INC

    Abstract: A cytological analysis test for 3D cell classification from a specimen. The method includes isolating and preserving cells from the specimen and enriching the cells before embedding the enriched cells into an optical medium. The embedded cells are injected into a capillary tube where pressure is applied until a cell appears in a field of view of a pseudo-projection viewing subsystem to acquire a pseudo-projection image. The capillary tube rotates about a tube axis to provide a set of pseudo-projection images for each embedded cell which are reconstructed to produce a set of 3D cell reconstructions. Reference cells are classified and enumerated and a second cell classifier detects target cells. An adequacy classifier compares the number of reference cells against a threshold value of enumerated reference cells to determine specimen adequacy.

    SYSTEM AND METHOD FOR DETERMINING CELL ADEQUACY IN A CYTOLOGICAL ANALYSIS SYSTEM

    公开(公告)号:CA2990624A1

    公开(公告)日:2017-01-05

    申请号:CA2990624

    申请日:2016-06-27

    Applicant: VISIONGATE INC

    Abstract: A cytological analysis test for 3D cell classification from a specimen. The method includes isolating and preserving cells from the specimen and enriching the cells before embedding the enriched cells into an optical medium. The embedded cells are injected into a capillary tube where pressure is applied until a cell appears in a field of view of a pseudo-projection viewing subsystem to acquire a pseudo-projection image. The capillary tube rotates about a tube axis to provide a set of pseudo-projection images for each embedded cell which are reconstructed to produce a set of 3D cell reconstructions. Reference cells are classified and enumerated and a second cell classifier detects target cells. An adequacy classifier compares the number of reference cells against a threshold value of enumerated reference cells to determine specimen adequacy.

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