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公开(公告)号：CA2854563A1
公开(公告)日：2013-05-16
申请号：CA2854563
申请日：2012-11-09
Applicant: WOOMERA THERAPEUTICS
Inventor： NORTH WILLIAM G , PANG ROY H L
IPC: A61K39/395 , A61K38/08 , A61K38/10 , A61K48/00 , A61P35/00
Abstract: Provided herein are pro- VP antagonists, such as antibodies and antigen-binding portions thereof specific for pro- VP, for identifying and targeting expressing cancer cells. Applicants additionally provide methods of using said compositions, for example to image cancer cells in vivo and in biological samples. The compositions may also be used for treating patients suffering from a provasopressin-expressing cancer. Provasopressin- expressing cancers include neuroendocrine cancer, pancreatic cancer, and prostate cancer.
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公开(公告)号：DE60335387D1
公开(公告)日：2011-01-27
申请号：DE60335387
申请日：2003-07-16
Applicant: WOOMERA THERAPEUTICS INC
Inventor： NORTH WILLIAM G , KEEGAN BRENDAN P , OLIGINO LYN
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3.发明专利
公开(公告)号：AU2003251966A1
公开(公告)日：2004-02-02
申请号：AU2003251966
申请日：2003-07-16
Applicant: WOOMERA THERAPEUTICS INC
Inventor： NORTH WILLIAM G , KEEGAN BRENDAN P , OLIGINO LYN
Abstract: The present invention discloses antibodies, antigen binding fragments, peptides and peptidomimetics immunoreactive with provasopressin and compositions thereof, methods of phenotyping tissue samples, methods of treating cancer, and kits for phenotyping test biopsy samples and bodily fluids for breast cancer, small cell lung cancer, ductal carcinoma in situ, and atypical ductal hyperplasia.
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4.发明申请
公开(公告)号：WO2013071038A3
公开(公告)日：2013-08-08
申请号：PCT/US2012064348
申请日：2012-11-09
Applicant: WOOMERA THERAPEUTICS
Inventor： NORTH WILLIAM G , PANG ROY H L
IPC: A61K38/08 , A61K39/395 , A61P35/00
CPC classification number: C07K16/2869 , A61K38/00 , A61K38/31 , A61K39/3955 , A61K45/06 , A61K49/0058 , A61K51/1036 , A61K51/1063 , A61K51/1096 , A61K2039/505 , A61K2039/507 , C07K7/06 , C07K14/4703 , C07K14/72 , C07K16/26 , C07K2317/34 , C07K2317/73 , C07K2317/92 , G01N33/57492 , A61K2300/00
Abstract: Provided herein are antagonists or binding agents of an abnormal vasopressin receptor V2 (e.g., AbnV2), such as antibodies and antigen-binding portions thereof specific for the receptor, for identifying and targeting cancer cells expressing such abnormal vasopressin receptor V2. Additionally provided are methods of using said antagonists or binding agents, for example, to image cancer cells or in biological samples, or diagnose cancers, both in vivo and in vitro. The antagonists or binding agents may also be used for treating patients suffering from a cancer expressing the abnormal vasopressin receptor V2, such as small cell lung cancer (SCLC), breast cancer, or ovarian cancer.
Abstract translation: 本文提供的是异常加压素受体V2（例如，AbnV2）的拮抗剂或结合剂，例如抗体和针对受体特异性的抗原结合部分，用于鉴定和靶向表达这种异常加压素受体V2的癌细胞。 另外提供了使用所述拮抗剂或结合剂的方法，例如在体内和体外成像癌细胞或生物样品或诊断癌症。 拮抗剂或结合剂也可用于治疗患有表达异常加压素受体V2的癌症患者，例如小细胞肺癌（SCLC），乳腺癌或卵巢癌。
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公开(公告)号：AU2012335618A1
公开(公告)日：2014-06-12
申请号：AU2012335618
申请日：2012-11-09
Applicant: WOOMERA THERAPEUTICS
Inventor： NORTH WILLIAM G , PANG ROY H L
IPC: A61K38/08 , A61K39/395 , A61P35/00
Abstract: Provided herein are antagonists or binding agents of an abnormal vasopressin receptor V2 (e.g., AbnV2), such as antibodies and antigen-binding portions thereof specific for the receptor, for identifying and targeting cancer cells expressing such abnormal vasopressin receptor V2. Additionally provided are methods of using said antagonists or binding agents, for example, to image cancer cells or in biological samples, or diagnose cancers, both in vivo and in vitro. The antagonists or binding agents may also be used for treating patients suffering from a cancer expressing the abnormal vasopressin receptor V2, such as small cell lung cancer (SCLC), breast cancer, or ovarian cancer.
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Patent Agency Ranking
公开(公告)号：CA2854467A1
公开(公告)日：2013-05-16
申请号：CA2854467
申请日：2012-11-09
Applicant: WOOMERA THERAPEUTICS
Inventor： NORTH WILLIAM G , PANG ROY H L
IPC: A61K38/08 , A61K39/395 , A61P35/00
Abstract: Provided herein are antagonists or binding agents of an abnormal vasopressin receptor V2 (e.g., AbnV2), such as antibodies and antigen-binding portions thereof specific for the receptor, for identifying and targeting cancer cells expressing such abnormal vasopressin receptor V2. Additionally provided are methods of using said antagonists or binding agents, for example, to image cancer cells or in biological samples, or diagnose cancers, both in vivo and in vitro. The antagonists or binding agents may also be used for treating patients suffering from a cancer expressing the abnormal vasopressin receptor V2, such as small cell lung cancer (SCLC), breast cancer, or ovarian cancer.
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7.发明专利
公开(公告)号：CA2492475A1
公开(公告)日：2004-01-22
申请号：CA2492475
申请日：2003-07-16
Applicant: WOOMERA THERAPEUTICS INC
Inventor： KEEGAN BRENDAN P , NORTH WILLIAM G , OLIGINO LYN
IPC: A61K47/48 , A61K49/00 , A61K51/10 , C07K16/30 , A61P35/00 , C07K7/08 , A61K38/10 , C12N15/13 , A61K39/395 , G01N33/574
Abstract: The present invention discloses antibodies, antigen binding fragments, peptides and peptidomimetics immunoreactive with provasopressin and compositions thereof, methods of phenotyping tissue samples, methods of treating cancer, and kits for phenotyping test biopsy samples and bodily fluids for breast cancer, small cell lung cancer, ductal carcinoma in situ, and atypical ductal hyperplasia.
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8.发明申请PEPTIDES, ANTIBODIES, AND USES THEREOF FOR IDENTIFYING AND TARGETING PROVASOPRESSIN-EXPRESSING CANCER CELLS 审中-公开肽，抗体及其用于鉴定和靶向预防癌症的癌细胞的用途
公开(公告)号：WO2009137113A2
公开(公告)日：2009-11-12
申请号：PCT/US2009002938
申请日：2009-05-11
Applicant: WOOMERA THERAPEUTICS INC , NORTH WILLIAM G , PANG ROY
Inventor： NORTH WILLIAM G , PANG ROY
IPC: C07K16/00
CPC classification number: C07K16/30 , A61K47/6851 , A61K47/6857 , A61K49/0002 , A61K49/085 , A61K49/16 , A61K51/1045 , A61K51/1054 , A61K2039/505 , C07K14/575 , C07K16/3023 , C07K2317/34 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/57415 , G01N33/57423 , G01N33/57438 , G01N33/6893 , G01N2333/575 , G01N2800/365
Abstract: This application provides peptides, antibodies, and antigen-binding portions thereof, for identifying and targeting provasopressin-expressing cancer cells. Also provided are methods of using said compositions, for example to image cancer cells in vivo and in biological samples. Also provided are methods of using said compositions for treating patients suffering from a provasopressin-associated cancers, including breast cancer and small cell lung cancer.
Abstract translation: 该应用提供肽，抗体及其抗原结合部分，用于鉴定和靶向表达加强素的癌细胞。 还提供了使用所述组合物的方法，例如在体内和生物样品中成像癌细胞。 还提供了使用所述组合物治疗患有与加压素相关的癌症（包括乳腺癌和小细胞肺癌）的患者的方法。
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9.发明申请COMPOSITIONS AND USES THEREOF FOR IDENTIFYING AND TARGETING PROVASOPRESSIN-EXPRESSING CANCER CELLS 审中-公开用于鉴定和靶向预防癌症表达癌细胞的组合物及其用途
公开(公告)号：WO2004006860A3
公开(公告)日：2005-02-03
申请号：PCT/US0322264
申请日：2003-07-16
Applicant: WOOMERA THERAPEUTICS INC , NORTH WILLIAM G , KEEGAN BRENDAN P , OLIGINO LYN
Inventor： NORTH WILLIAM G , KEEGAN BRENDAN P , OLIGINO LYN
CPC classification number: A61K49/0041 , A61K47/6817 , A61K49/0043 , A61K49/0058 , A61K51/10 , A61K2039/505 , C07K16/26 , C07K16/30 , C07K16/3023 , C07K2317/55
Abstract: The present invention discloses antibodies, antigen binding fragments, peptides and peptidomimetics immunoreactive with provasopressin and compositions thereof, methods of phenotyping tissue samples, methods of treating cancer, and kits for phenotyping test biopsy samples and bodily fluids for breast cancer, small cell lung cancer, ductal carcinoma in situ, and atypical ductal hyperplasia.
Abstract translation: 本发明公开了抗体，抗原结合片段，肽和拟肽与免疫反应性与前列腺素加成素及其组合物，表型组织样品的方法，治疗癌症的方法，以及用于表型测试活检样本和乳腺癌体液，小细胞肺癌， 导管原位癌和非典型性导管增生。
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公开(公告)号：EP2776064A4
公开(公告)日：2015-08-05
申请号：EP12847111
申请日：2012-11-09
Applicant: WOOMERA THERAPEUTICS
Inventor： NORTH WILLIAM G , PANG ROY H L
CPC classification number: C07K16/26 , A61K31/137 , A61K38/10 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/48553 , A61K47/6847 , A61K49/00 , A61K51/1024 , A61K2039/505 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/55 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57415 , G01N33/57423 , A61K2300/00
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