公开(公告)号：WO2019204729A1

公开(公告)日：2019-10-24

申请号：PCT/US2019/028324

申请日：2019-04-19

Applicant: WORCESTER POLYTECHNIC INSTITUTE

Inventor： LOZEAU, Lindsay D. ,  HANSON, Abigail ,  MACE, Joshua B. ,  METTERS, Frederick T. ,  SHERLOCK, Nicole ,  CAMESANO, Terri A. ,  ROLLE, Marsha W.

IPC: A61K9/00 ,  A61Q17/00 ,  C07K14/47 ,  C07K14/78

Abstract: Aspects of the disclosure relate to a topical composition comprising (1) at least one fusion peptide comprising at least one antimicrobial peptide and at least one peptide capable of improving the stability, the activity or the stability and the activity of the antimicrobial peptide in a hydrophobic environment, (2) at least one essential oil, wherein the composition comprises the at least one fusion peptide and the at least one essential oil at concentrations capable of providing synergistic anti-inflammatory activity and/or antimicrobial activity.