-
公开(公告)号：US12280177B2
公开(公告)日：2025-04-22
申请号：US17388652
申请日：2021-07-29
Applicant: Wisconsin Alumni Research Foundation , ARKANSAS STATE UNIVERSITY—JONESBORO , Worcester Polytechnic Institute
Inventor： William L. Murphy , Gianluca Fontana , Joshua Gershlak , Glenn Gaudette , Pam Weathers , Tanja Dominko , Marsha Rolle , Sarah Hernandez , Carol Cramer , Luis Fabircio Medina-Bolivar , Bernard Binder
Abstract: Decellularized plant tissues and the use of these plant tissues as scaffolds are disclosed herein. Particularly, decellularized plant tissues are functionalized such to allow for human cell adhesion, thereby allowing for their use as scaffolds for human cells. These scaffolds can then be used in a number of applications/markets, including as research tools for tissue engineering, regenerative medicine, and basic cellular biology.
-
Patent Agency Ranking
公开(公告)号：US20210348129A1
公开(公告)日：2021-11-11
申请号：US17317037
申请日：2021-05-11
Applicant: Worcester Polytechnic Institute
Inventor： Alex S. Rebello , Jordan Jones , Glenn Gaudette
IPC: C12N5/077 , A23L13/00 , A23L33/105 , A23L19/00
Abstract: An in vitro meat having non-decellularized leaf scaffold and a method for producing an in vitro meat using non-decellularized leaf scaffold are described herein. The method includes preparing a non-decellularized plant leaf and incubating the leaf in a cell culture media to obtain a non-decellularized leaf scaffold; seeding the leaf scaffold with a population of muscle cells to obtain a leaf scaffold adhered population of muscle cells; and growing the leaf scaffold adhered population of muscle cells in cell culture media thereby obtaining the in vitro meat.
-
3.发明申请公开(公告)号：US20220054710A1
公开(公告)日：2022-02-24
申请号：US17465102
申请日：2021-09-02
Applicant: Worcester Polytechnic Institute
Inventor： Jeannine Coburn , Glenn Gaudette , Nhi Phan
Abstract: Provided herein are enzymatically decellularized cells, and methods of producing said cells, that can be used in a scaffold. The scaffolds featured herein are biocompatible and can comprise decellularized cells that have been modified to express a bioactive agent or molecule.
-
4.发明申请公开(公告)号：US20200061245A1
公开(公告)日：2020-02-27
申请号：US16548510
申请日：2019-08-22
Applicant: Worcester Polytechnic Institute
Inventor： Jeannine Coburn , Glenn Gaudette , Nhi Phan
Abstract: Provided herein are enzymatically decellularized cells, and methods of producing said cells, that can be used in a scaffold. The scaffolds featured herein are biocompatible and can comprise decellularized cells that have been modified to express a bioactive agent or molecule.
-
公开(公告)号：US20150005739A1
公开(公告)日：2015-01-01
申请号：US14296109
申请日：2014-06-04
Applicant: Worcester Polytechnic Institute
Inventor： Glenn Gaudette , George D. Pins , Marsha Rolle , Jacques P. Guyette , Kevin Cornwall
CPC classification number: A61L31/046 , A61B17/0469 , A61B17/06 , A61B17/06166 , A61B2017/00243 , A61B2017/00893 , A61L27/225 , A61L27/3826 , A61L27/3834 , A61L27/3873 , A61L31/16 , A61L2430/20 , C12N5/0068 , C12N11/02 , C12N2533/56
Abstract: Compositions that include microthreads are provided. The compositions can be fully or partially encased in a sleeve along at least a portion of their length and can include biological cells and, optionally, therapeutic agents. Also provided are methods for using the compositions to repair or ameliorate damaged or defective tissue, including cardiovascular tissue (e.g., the myocardium).
Abstract translation: 提供包括微丝的组合。 组合物可以沿其长度的至少一部分完全或部分地包封在套管中，并且可以包括生物细胞和任选的治疗剂。 还提供了使用组合物来修复或改善包括心血管组织（例如心肌）的损伤或缺陷组织的方法。
-
6.发明授权公开(公告)号：US11110203B2
公开(公告)日：2021-09-07
申请号：US16548510
申请日：2019-08-22
Applicant: Worcester Polytechnic Institute
Inventor： Jeannine Coburn , Glenn Gaudette , Nhi Phan
Abstract: Provided herein are enzymatically decellularized cells, and methods of producing said cells, that can be used in a scaffold. The scaffolds featured herein are biocompatible and can comprise decellularized cells that have been modified to express a bioactive agent or molecule.
-
-
-
-
-
Search Results
6
records
(took 0.022 seconds)
