公开(公告)号：DE60126557D1

公开(公告)日：2007-03-29

申请号：DE60126557

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： HORINE DAVID A ,  HADIMIOGLU BABUR B ,  BRUCE RICHARD H ,  ELROD SCOTT A ,  NOOLANDI JAAN

IPC: G01N33/48 ,  B01L3/02 ,  B41J2/045 ,  B41J2/055 ,  B41J2/14 ,  B41J2/17 ,  B41J2/175 ,  G01F23/00 ,  G01N33/53 ,  G01N35/10 ,  G01N37/00

Abstract: A level control mechanism is provided for a biofluid drop ejection device which ejects biofluid drops in small volumes. The biofluid drop device includes a drop ejection mechanism having a transducer (16) which generates energy used to emit the biofluid drops. A reagent cartridge (12) or biofluid holding area holds a biofluid, isolated from the drop ejection mechanism to avoid contamination between the biofluid drop ejection mechanism and the reagent cartridge. The reagent cartridge is connected to the drop ejection mechanism such that upon operation of the mechanism, the biofluid is emitted in controlled biofluid drops. A level sensor is positioned to sense a height of the biofluid within the cartridge. Upon sensing the height of the biofluid below a certain level, an adjustment is made to the height by providing at least one of additional biofluid to the cartridge, and raising the level of the entire reagent cartridge.

公开(公告)号：DE60123735T2

公开(公告)日：2007-01-18

申请号：DE60123735

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： ELROD SCOTT A ,  ROY JOY ,  HADIMIOGLU BABUR B ,  BRUCE RICHARD H ,  NOOLANDI JAAN ,  HORINE DAVID A

IPC: B01L3/02 ,  C12M1/00 ,  B05B1/04 ,  B05B17/06

Abstract: Provided is a priming mechanism for priming a biofluid drop ejection device having a drop ejection opening leading to an ejection reservoir. The priming mechanism includes a vacuum unit which generates a vacuum force, connected to a vacuum nozzle. The vacuum nozzle is located over the drop ejection opening. A disposable sleeve or tubing is attached to the vacuum nozzle and is placed in operational contact with the drop ejection opening. A fluid height detection sensor is positioned to sense a fluid height within at least one of the disposable tubing and the vacuum nozzle. Upon sensing a predetermined fluid height, by the fluid height detection sensor, the priming operation is completed, and the primer mechanism is removed from the operational contact with the drop ejection opening.

公开(公告)号：DE60123735D1

公开(公告)日：2006-11-23

申请号：DE60123735

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： ELROD SCOTT A ,  ROY JOY ,  HADIMIOGLU BABUR B ,  BRUCE RICHARD H ,  NOOLANDI JAAN ,  HORINE DAVID A

IPC: B01L3/02 ,  C12M1/00 ,  B05B1/04 ,  B05B17/06

Abstract: Provided is a priming mechanism for priming a biofluid drop ejection device having a drop ejection opening leading to an ejection reservoir. The priming mechanism includes a vacuum unit which generates a vacuum force, connected to a vacuum nozzle. The vacuum nozzle is located over the drop ejection opening. A disposable sleeve or tubing is attached to the vacuum nozzle and is placed in operational contact with the drop ejection opening. A fluid height detection sensor is positioned to sense a fluid height within at least one of the disposable tubing and the vacuum nozzle. Upon sensing a predetermined fluid height, by the fluid height detection sensor, the priming operation is completed, and the primer mechanism is removed from the operational contact with the drop ejection opening.

公开(公告)号：DE60126557T2

公开(公告)日：2007-05-31

申请号：DE60126557

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： HORINE DAVID A ,  HADIMIOGLU BABUR B ,  BRUCE RICHARD H ,  ELROD SCOTT A ,  NOOLANDI JAAN

IPC: G01N33/48 ,  B01L3/02 ,  B41J2/045 ,  B41J2/055 ,  B41J2/14 ,  B41J2/17 ,  B41J2/175 ,  G01F23/00 ,  G01N33/53 ,  G01N35/10 ,  G01N37/00

Abstract: A level control mechanism is provided for a biofluid drop ejection device which ejects biofluid drops in small volumes. The biofluid drop device includes a drop ejection mechanism having a transducer (16) which generates energy used to emit the biofluid drops. A reagent cartridge (12) or biofluid holding area holds a biofluid, isolated from the drop ejection mechanism to avoid contamination between the biofluid drop ejection mechanism and the reagent cartridge. The reagent cartridge is connected to the drop ejection mechanism such that upon operation of the mechanism, the biofluid is emitted in controlled biofluid drops. A level sensor is positioned to sense a height of the biofluid within the cartridge. Upon sensing the height of the biofluid below a certain level, an adjustment is made to the height by providing at least one of additional biofluid to the cartridge, and raising the level of the entire reagent cartridge.

公开(公告)号：DE60126227D1

公开(公告)日：2007-03-15

申请号：DE60126227

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： HADIMIOGLU BABUR B ,  ELROD SCOTT A ,  BRUCE RICHARD H ,  HORINE DAVID A ,  NOOLANDI JAAN

IPC: B01L3/02 ,  G01N33/53 ,  G01N1/00 ,  G01N35/10 ,  G01N37/00

Abstract: A multiple-ejector system for printing arrays of biofluids include a tooling plate having a plurality of sets of tooling pins extending outward from the surface of the tooling plate. A printed circuit board is provided having pairs of power connection pins and ground return pins extending from a surface of the circuit board. A plurality of biofluid drop ejection units are provided and include alignment grooves and at least a transducer. Each of the plurality of biofluid drop ejection units are connected to a corresponding one of a set of tooling pins by connection of the tooling pins and alignment grooves. The power connection pins of the pairs are in operational connection with respective transducers and the ground return connection pins of the pairs are in operational connection with a body portion of the drop ejection units. The different drop ejection units will contain different biofluids which are to be emitted onto a substrate. Verification of drop ejection units containing biofluids, may be obtained in one embodiment through the use of an optical scanner. Detection of drops at defined locations provides a verification that validates a properly formed spot is present on a substrate, and is in the correct position.

公开(公告)号：DE69825844D1

公开(公告)日：2004-09-30

申请号：DE69825844

申请日：1998-11-23

Applicant: XEROX CORP

Inventor： HORINE DAVID A

IPC: C23C4/12

Abstract: A method for manufacturing precise complex three dimensional structures in which minute drops of both a product layer and a sacrificial layer are emitted from an acoustic device. The process is a two step process wherein first the three dimensional structure is built in layers which are composed of either a sacrificial layer or a product layer or some configuration of both. Once the structure has been completely built up, then the sacrificial layer is removed leaving only the complex three dimensional structure.

公开(公告)号：DE69824370D1

公开(公告)日：2004-07-15

申请号：DE69824370

申请日：1998-11-23

Applicant: XEROX CORP

Inventor： HORINE DAVID A

IPC: B41J2/14 ,  C23C4/12 ,  H05K3/14 ,  H05K3/34

公开(公告)号：DE60126227T2

公开(公告)日：2007-10-31

申请号：DE60126227

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： HADIMIOGLU BABUR B ,  ELROD SCOTT A ,  BRUCE RICHARD H ,  HORINE DAVID A ,  NOOLANDI JAAN

IPC: B01L3/02 ,  G01N33/53 ,  G01N1/00 ,  G01N35/10 ,  G01N37/00

Abstract: A multiple-ejector system for printing arrays of biofluids include a tooling plate having a plurality of sets of tooling pins extending outward from the surface of the tooling plate. A printed circuit board is provided having pairs of power connection pins and ground return pins extending from a surface of the circuit board. A plurality of biofluid drop ejection units are provided and include alignment grooves and at least a transducer. Each of the plurality of biofluid drop ejection units are connected to a corresponding one of a set of tooling pins by connection of the tooling pins and alignment grooves. The power connection pins of the pairs are in operational connection with respective transducers and the ground return connection pins of the pairs are in operational connection with a body portion of the drop ejection units. The different drop ejection units will contain different biofluids which are to be emitted onto a substrate. Verification of drop ejection units containing biofluids, may be obtained in one embodiment through the use of an optical scanner. Detection of drops at defined locations provides a verification that validates a properly formed spot is present on a substrate, and is in the correct position.

公开(公告)号：DE69824370T2

公开(公告)日：2004-10-07

申请号：DE69824370

申请日：1998-11-23

Applicant: XEROX CORP

Inventor： HORINE DAVID A

IPC: B41J2/14 ,  C23C4/12 ,  H05K3/14 ,  H05K3/34

公开(公告)号：DE60119874T2

公开(公告)日：2006-09-28

申请号：DE60119874

申请日：2001-11-13

Applicant: XEROX CORP

Inventor： BRUCE RICHARD H ,  ELROD SCOTT A ,  HORINE DAVID A ,  HADIMIOGLU BABUR B ,  NOOLANDI JAAN

IPC: B01L3/02 ,  G01N1/00 ,  B01J19/00 ,  B41J2/00 ,  B41J2/14 ,  C40B60/14 ,  G01N35/00 ,  G01N35/10 ,  G01N37/00

Abstract: Methods for testing proper operation of drop ejection units in a multi-ejector system are provided to determine whether the drop ejectors have been properly filled and/or the ejectors are emitting fully formed droplets. The method include testing the ejectors prior to drop ejection. In this method, a priming system is ejected onto a test substrate to allow a scanner to determine the existence of the fluids at selected locations.