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1.发明授权Cell membrane proteins, compositions containing them and procedure for their preparation 失效细胞膜蛋白，包含它们的组合物及其制备方法
公开(公告)号：EP0261648B1
公开(公告)日：1992-12-09
申请号：EP87113856.6
申请日：1987-09-22
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Cohen, Irun Robert , Shinitzky, Meir
CPC classification number: A61K39/0008 , A61K35/17 , A61K2039/5158 , C12N5/0636 , C12N2521/00
Abstract: Compositions for the prevention and treatment of autoimmune diseases are provided which comprise as an active ingredient membrane material shed from autoimmune T lymphocytes, or activated T lymphocytes which are treated by a pressure application and release process. There is also provided processes for obtaining such active materials and for preparing pharmaceutical compositions containing them.
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2.发明公开Novel lipid fraction, its preparation and pharmaceutical compositions containing same 失效新脂质级分，其制备方法和含有它们的药物组合物。
公开(公告)号：EP0074251A1
公开(公告)日：1983-03-16
申请号：EP82304626.3
申请日：1982-09-02
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Shinitzky, Meir , Heron, David , Samuel, David
Abstract: The invention concerns a lipid fraction (AL) derived from natural sources which can be used for in vitro and in vitro treatment of a variety of disorders. The lipid fraction contains 40-80 weight percent glycerides, 3-5 weight percent cholesterol, 10-30 weight percent lecithin (phosphatidyl choline), 5-15 weight percent phosphatidyl ethanolamine and 2-5 weight percent negatively charged phospholipids, wherein the ratio of unsaturated to saturated fatty acids is at least 1:1.
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Patent Agency Ranking3.发明公开Cell membrane proteins, compositions containing them and procedure for their preparation 失效细胞膜蛋白，包含它们的组合物及其制备方法
公开(公告)号：EP0261648A3
公开(公告)日：1989-06-07
申请号：EP87113856.6
申请日：1987-09-22
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Cohen, Irun Robert , Shinitzky, Meir
CPC classification number: A61K39/0008 , A61K35/17 , A61K2039/5158 , C12N5/0636 , C12N2521/00
Abstract: Compositions for the prevention and treatment of autoimmune diseases are provided which comprise as an active ingredient membrane material shed from autoimmune T lymphocytes, or activated T lymphocytes which are treated by a pressure application and release process. There is also provided processes for obtaining such active materials and for preparing pharmaceutical compositions containing them.
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4.发明公开Cell membrane proteins, compositions containing them and procedure for their preparation 失效细胞膜蛋白质，含有它们的它们的制备方法的准备。
公开(公告)号：EP0261648A2
公开(公告)日：1988-03-30
申请号：EP87113856.6
申请日：1987-09-22
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Cohen, Irun Robert , Shinitzky, Meir
CPC classification number: A61K39/0008 , A61K35/17 , A61K2039/5158 , C12N5/0636 , C12N2521/00
Abstract: Compositions for the prevention and treatment of autoimmune diseases are provided which comprise as an active ingredient membrane material shed from autoimmune T lymphocytes, or activated T lymphocytes which are treated by a pressure application and release process. There is also provided processes for obtaining such active materials and for preparing pharmaceutical compositions containing them.
Abstract translation: 提供了用于自身免疫性疾病的预防和治疗组合物作为自体免疫Ť棚活性成分的膜材料的淋巴细胞，其包含，或活化其通过施加压力和释放过程处理的T淋巴细胞。 因此，存在用于获得寻求的活性材料和用于制备含有它们的药物组合物提供的方法。
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5.发明授权Novel lipid fraction, its preparation and pharmaceutical compositions containing same 失效新型脂肪分级，其制备和含有相同的药物组合物
公开(公告)号：EP0074251B1
公开(公告)日：1985-04-03
申请号：EP82304626.3
申请日：1982-09-02
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Shinitzky, Meir , Heron, David , Samuel, David
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6.发明授权Novel lipid fraction, its preparation and pharmaceutical compositions containing same 失效新型脂肪分级，其制备和含有相同的药物组合物
公开(公告)号：EP0074251B2
公开(公告)日：1991-01-30
申请号：EP82304626.3
申请日：1982-09-02
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Shinitzky, Meir , Heron, David , Samuel, David
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7.发明公开
公开(公告)号：EP0213724A1
公开(公告)日：1987-03-11
申请号：EP86305736.0
申请日：1986-07-25
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Shinitzky, Meir
IPC: A61K31/685
CPC classification number: A61K31/685 , A61K31/23 , A61K2300/00
Abstract: A special lipid mixture for membrane fluidization consisting essentially of about seven parts by weight neutral lipids and about three parts by weight phospholipids, the phospholipids consisting essentially of phosphatidyl choline and phosphatidyl ethanolamine, and the neutral lipids consisting essentially of glycerides.
Abstract translation: 用于膜流态化的特殊脂质混合物基本上由约7重量份的中性脂质和约3重量份的磷脂组成，磷脂基本上由磷脂酰胆碱和磷脂酰乙醇胺组成，并且基本上由甘油酯组成的中性脂质。
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