公开(公告)号：EP4411349A1

公开(公告)日：2024-08-07

申请号：EP23305149.9

申请日：2023-02-03

Applicant: Merck Patent GmbH

Inventor： PUGET, Renaud ,  THOMAS, Fabrice ,  DUCHEMIN, Céline ,  SANCHEZ, Célia ,  JOURDAINNE, Laurent

IPC: G01N21/65

CPC classification number: G01N21/65 ,  G01N2201/1220130101

Abstract: A system and method for quantifying the stray light that enters a Raman optical sensor and removes this from the Raman spectrum is disclosed. One or more background noise measurements are performed by the Raman analyzer wherein the laser is disabled during these background noise measurements. One or more traditional signal acquisition measurements are then performed. The results from the background noise measurements and the traditional signal acquisition measurement are then processed. This results in a clean spectrum, where the background noise has been significantly reduced. In some embodiments, background noise measurements are performed before and after the traditional signal acquisition measurement and these noise measurements are averaged.

公开(公告)号：EP3314253B9

公开(公告)日：2024-08-07

申请号：EP16815454.0

申请日：2016-06-24

IPC: G01N21/31 ,  G01J3/433 ,  G01N33/49 ,  A61M1/14 ,  A61B5/00 ,  G01J1/44 ,  G01J1/46 ,  G01J3/10 ,  A61B5/026 ,  A61B5/1455 ,  A61B5/145 ,  A61M1/36

CPC classification number: G01J3/433 ,  G01N21/31 ,  G01N2021/318120130101 ,  G01N2201/062720130101 ,  A61B5/0059 ,  A61B5/0084 ,  A61B5/0261 ,  A61M1/14 ,  A61M1/3627 ,  A61B5/14542 ,  A61B5/14551 ,  A61M2205/331320130101 ,  A61M2230/2020130101 ,  A61M2230/20220130101 ,  A61M2230/20520130101 ,  A61M2230/20720130101 ,  G01N2201/069120130101 ,  G01J2001/440620130101 ,  G01J1/44 ,  G01J1/46 ,  G01J3/10 ,  G01J3/108 ,  G01J3/4338 ,  G01J2003/10420130101 ,  G01J2003/10620130101 ,  G01J2003/433420130101 ,  G01N33/49 ,  G01N2201/1220130101

公开(公告)号：EP3286780B1

公开(公告)日：2024-07-31

申请号：EP16783746.7

申请日：2016-04-20

IPC: H01L21/66 ,  G01N23/203 ,  G01N21/93 ,  G01N21/95 ,  G02B13/00 ,  G01N21/956

CPC classification number: G01N21/95607 ,  G01N21/93 ,  G01N21/9501 ,  G01N2201/10620130101 ,  G01N2201/1220130101

公开(公告)号：EP4390376A1

公开(公告)日：2024-06-26

申请号：EP22306979.0

申请日：2022-12-21

Applicant: BIOMÉRIEUX

Inventor： ROSSI, Veronica Lucia ,  SANESI, Antonio ,  FERORELLI, Giuseppe ,  CHINI, Giorgio ,  MECOCCI, Alessandro ,  ANDREINI, Paolo ,  BONECHI, Simone

IPC: G01N21/64 ,  G01N21/03

CPC classification number: G01N21/6456 ,  G01N2201/129620130101 ,  G01N2021/648220130101 ,  G01N2021/038220130101 ,  G01N2201/1220130101

Abstract: It is disclosed a method for performing fluorescence measurement on a sample, comprising:
- Illuminating the sample using a light source,
- acquiring at least one fluorescence image of the illuminated sample, and
- processing the fluorescence image to determine a fluorescence intensity of the sample,
characterized in that processing the fluorescence image to determine a fluorescence intensity of the sample comprises:
- extracting, from the fluorescence image, a region of interest (ROI) free from artefacts, by application of a trained model, and
- determining the fluorescence intensity of the sample from the extracted region of interest.