公开(公告)号：WO1998006327A1

公开(公告)日：1998-02-19

申请号：PCT/US1997013743

申请日：1997-08-05

Applicant: VITAL INSITE, INC.

Inventor： VITAL INSITE, INC. ,  FLAHERTY, Bryan, P. ,  SHER, Mark, H. ,  CARO, Richard, G.

IPC: A61B05/0245

CPC classification number: A61B5/02007 ,  A61B5/02133 ,  A61B5/022 ,  A61B5/02225 ,  A61B5/024 ,  A61B5/6824 ,  A61B5/7207 ,  A61B5/7228 ,  A61B8/04 ,  A61B8/488

Abstract: A motion insensitive pulse detector for detecting a patient's pulse includes an exciter adapted to be positioned over a blood vessel of the patient and configured to induce a transmitted exciter waveform into the patient. A noninvasive sensor is adapted to be positioned over the blood vessel and configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of the hemoparameter containing a component of a received exciter waveform. A processor is coupled to the noninvasive sensor and configured to process the noninvasive sensor signal to determine the patient's pulse. Advantages of the invention include the ability to detect a patient's pulse even when the patient is moving or being moved by medical personnel.

Abstract translation: 用于检测患者脉搏的运动不敏感脉冲检测器包括适于定位在患者的血管上并被配置为将传输的激励器波形诱导到患者体内的激励器。 非侵入式传感器适于定位在血管上方并且被配置为感测血液参数并且产生代表包含接收的激励器波形的分量的血液参数的无创传感器信号。 处理器耦合到无创传感器并且被配置为处理无创传感器信号以确定患者的脉搏。 本发明的优点包括甚至当患者正在由医务人员移动或移动时检测患者脉搏的能力。

公开(公告)号：WO1997012546A1

公开(公告)日：1997-04-10

申请号：PCT/US1996015995

申请日：1996-10-04

Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Inventor： MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  ALBRECHT, Paul ,  BIGGER, J., Thomas ,  COHEN, Richard, J.

IPC: A61B05/0245

CPC classification number: A61B5/0245 ,  A61B5/7275 ,  G06F19/00

Abstract: The method for assessing risk of an adverse clinical event includes detecting a physiologic signal in the subject and determining from the physiologic signal a sequence of intervals corresponding to time intervals between heart beats. The long-time structure of fluctuations in the intervals over a time period of more than fifteen minutes is analyzed to assess risk of an adverse clinical event. In a preferred embodiment, the physiologic signal is an electrocardiogram and the time period is at least fifteen minutes. A preferred method for analyzing the long-time structure variability in the intervals includes computing the power spectrum and fiitting the power spectrum to a power law dependence on frequency over a selected frequency range such as 10 to 10 Hz. Characteristics of the long-time structure fluctuations in the intervals is used to assess risk of an adverse clinical event.

Abstract translation: 用于评估不利临床事件的风险的方法包括检测受试者的生理信号，并根据生理信号确定与心跳之间的时间间隔相对应的间隔序列。 分析超过15分钟的时间段间隔波动的长期结构，以评估不良临床事件的风险。 在优选实施例中，生理信号是心电图，并且时间段至少为十五分钟。 用于分析间隔中的长时间结构变异性的优选方法包括计算功率谱并将功率谱转换为在所选频率范围（例如10 -4至10 -2 Hz）上的频率的幂律依赖性 。 间隔时间长时间结构波动的特征用于评估不良临床事件的风险。

公开(公告)号：WO1997038627A1

公开(公告)日：1997-10-23

申请号：PCT/GB1997001043

申请日：1997-04-15

Applicant: THE VICTORIA UNIVERSITY OF MANCHESTER ,  POMFRETT, Christopher

Inventor： THE VICTORIA UNIVERSITY OF MANCHESTER

IPC: A61B05/0245

CPC classification number: A61B5/0245 ,  A61B5/4088

Abstract: A method for detecting the presence of a degenerative brain disease such as BSE or CJD. A measurement is made of the respiratory sinus arrhythmia of any mammal which is suspected of suffering from the degenerative brain disease. It is assumed that the mammal is suffering from such a disease if the measured RSA is outside a predetermined reference range. The reference range may be determined from data which forms the basis for the calculation of the RSA range by applying a suitable test for randomness.

Abstract translation: 用于检测退行性脑疾病如BSE或CJD的存在的方法。 测量任何怀疑患有退行性脑疾病的哺乳动物的呼吸道窦性心律失常。 如果测量的RSA在预定的参考范围之外，则假定哺乳动物患有这种疾病。 可以通过对随机性进行适当的测试来形成用于计算RSA范围的基础的数据来确定参考范围。

公开(公告)号：WO1996029005A1

公开(公告)日：1996-09-26

申请号：PCT/JP1996000661

申请日：1996-03-15

Applicant: CITIZEN WATCH CO., LTD. ,  KIHARA, Hiroyuki ,  MURAKAMI, Tomomi ,  OSA, Takashi ,  OKIGAMI, Tomio

Inventor： CITIZEN WATCH CO., LTD.

IPC: A61B05/0245

CPC classification number: A61B5/681 ,  A61B5/0006 ,  A61B5/02438 ,  A61B5/0245 ,  A61B5/222 ,  A61B5/6831 ,  Y10S128/903

Abstract: This invention aims at improving a method of carrying out communication between a transmission unit and a reception unit in a pulse rate meter and providing a pulse rate meter not influenced by noise. To achieve these objects, the present invention provides a pulse rate meter comprising a transmission unit provided with a detecting circuit for detecting an electrocardiographic signal obtained from a pair of electrodes fixed to the portion of a human body which is in the vicinity of the heart (2), and generating a detected signal (3), an interval data preparation circuit for counting the generation interval of the detected signals by a signal of a predetermined cycle and generating interval data (4), a serial data preparation circuit for converting the interval date into a serial signal and generating serial data signal (5), a transmission circuit for modulating the serial data signal and transmit the resultant signal as a ratio signal (6), and a battery as a power source (7), and a reception unit provided with a reception circuit for receiving the radio signal from the transmission unit, demodulating the resultant signal and generating a reception signal (8), a data decoding circuit for decoding the reception signal and generating electrocardiographic interval data (9), an operation circuit for calculating a heart rate on the basis of the electrocardiographic interval data, and a display for indicating a heart rate thereon. According to the present invention, even when the reception circuit receives noise or a signal having no relation with a heart rate, which does not constitute correct data in this case, it cannot be decoded correctly by the decoding circuit, and the data received normally in the preceding time are displayed. Therefore, erroneous heart rates are not displayed.

Abstract translation: 本发明旨在改进在脉搏计中的发送单元与接收单元之间进行通信的方法，并提供不受噪声影响的脉搏计。 为了实现这些目的，本发明提供了一种脉搏率计，其包括发送单元，该发送单元设置有用于检测从固定在心脏附近的人体部分的一对电极获得的心电图信号的检测电路（ 产生检测信号（3），间隔数据准备电路，用于通过预定周期的信号对所检测信号的产生间隔进行计数并产生间隔数据（4）;串行数据准备电路，用于将间隔 日期为串行信号并产生串行数据信号（5），用于调制串行数据信号并将结果信号作为比率信号（6）发送的发送电路和作为电源（7）的电池，以及接收 设置有用于从发送单元接收无线电信号的接收电路，解调所得到的信号并产生接收信号（8），数据解码电路 用于对接收信号进行解码并产生心电图间隔数据（9），用于基于心电图间隔数据计算心率的运算电路和用于在其上指示心率的显示器。 根据本发明，即使在接收电路接收到噪声或与这种情况下不构成正确数据的心率无关的信号的情况下，也不能由解码电路正确解码，并且正常地接收数据 显示前面的时间。 因此，不会显示错误的心率。

公开(公告)号：WO1995007652A1

公开(公告)日：1995-03-23

申请号：PCT/FI1994000401

申请日：1994-09-13

Applicant: MYLLYMÄKI, Matti

IPC: A61B05/0245

CPC classification number: A61B5/681 ,  A61B5/0002 ,  A61B5/0533 ,  A61B5/1104 ,  A61B2505/07 ,  Y10S128/903

Abstract: A body-held monitoring device for a physical condition and/or a performance condition, comprising a plurality of transducers (3-6) each measuring various quantities indicating a physical condition and/or a performance condition, especially motoric activity, moisture and/or electric conductivity of the skin, surface temperature and heart rate. The transducers (3-6) are monitored by means of a microprocessor, having its algorithm adapted to provide information indicating the physical condition and/or performance condition of a monitored person in such a manner that a plurality of different transducer signals are used to compensate for the false data caused by an individual transducer.

Abstract translation: 一种用于物理状况和/或性能状况的身体监控装置，包括多个换能器（3-6），每个换能器测量指示身体状况和/或性能状况，特别是运动活动，水分和/或 皮肤电导率，表面温度和心率。 传感器（3-6）通过微处理器进行监视，其微处理器的算法适用于提供指示受监控人员的身体状况和/或性能状况的信息，使得多个不同的换能器信号被用于补偿 用于由单个换能器引起的假数据。

公开(公告)号：WO1990009757A1

公开(公告)日：1990-09-07

申请号：PCT/US1990001080

申请日：1990-03-02

Applicant: RESEARCH TRIANGLE INSTITUTE

Inventor： RESEARCH TRIANGLE INSTITUTE ,  KIZAKEVICH, Paul, N. ,  TEAGUE, Steve, M.

IPC: A61B05/0245

CPC classification number: A61B5/0535 ,  A61B5/7239

Abstract: A heart monitoring system for assessing a patient's cardiac condition. Bioimpedance components induce an electric current through the thorax of a patient's body and a first signal representing amplitude of transthoracic impedance as a function of time is obtained. Electrocardiograph components obtain an electrocardiograph signal from the patient simultaneously with the first signal. First processing circuitry (28) is connected to the bioimpedance components (24) for processing the first signal and producing therefrom a second signal representing cardiovascular hemodynamic changes as a function of time. Second processing circuitry (22) is connected to the electrocardiograph components for measuring changes in the electrocardiograph signal. An analyzer (14) is connected to the first and second processing circuits for producing an output indicating changes in a portion of the second signal over a period of time relative to changes in the electrocardiograph signal over the same period of time. A presentation device (16) presents a visualization of the output of the analyzer for use in providing an assessment of cardiac condition.