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公开(公告)号：US20180059010A1
公开(公告)日：2018-03-01
申请号：US15701006
申请日：2017-09-11
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, JR. , Gary Conrad Jensen
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
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公开(公告)号：US20200249150A1
公开(公告)日：2020-08-06
申请号：US16679728
申请日：2019-11-11
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, JR. , Gary Conrad Jensen
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
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Patent Agency Ranking
公开(公告)号：US20170192021A1
公开(公告)日：2017-07-06
申请号：US15394452
申请日：2016-12-29
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, JR. , Gary Conrad Jensen , Roland Lawrence Guilmet , Peter Michael Magnin
CPC classification number: G01N33/728 , G01N21/31 , G01N33/526
Abstract: A sensor and method for measuring bilirubin in a liquid sample are disclosed. The sensor comprises a substrate comprising a reservoir disposed within the substrate, the reservoir having a top surface and a bottom surface; a filter; at least one transparent portion, the transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector comprising at least a portion of the reservoir. The method for measuring bilirubin in a liquid sample comprises inserting a sensor into an analyzer; introducing the liquid sample to the sensor; filtering the liquid sample such that the sample flows into a reservoir in the sensor; illuminating the liquid sample in the sensor using a light source in the analyzer; measuring a reflectance of the liquid sample at one or more wavelengths using a detector in the analyzer; and computing a measurement of bilirubin using the measured reflectances.
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公开(公告)号：US09759651B2
公开(公告)日：2017-09-12
申请号：US14978292
申请日：2015-12-22
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, Jr. , Gary Conrad Jensen
IPC: G01N27/416 , G01N21/31 , G01N33/49 , G01N21/47
CPC classification number: G01N21/31 , G01N21/474 , G01N33/49 , G01N2201/062 , G01N2201/0625 , G01N2201/0696
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
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公开(公告)号：US20160178573A1
公开(公告)日：2016-06-23
申请号：US14978292
申请日：2015-12-22
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, JR. , Gary Conrad Jensen
IPC: G01N27/416 , G01N27/30 , G01N21/31 , G01N33/49 , G01N21/55
CPC classification number: G01N21/31 , G01N21/474 , G01N33/49 , G01N2201/062 , G01N2201/0625 , G01N2201/0696
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
Abstract translation: 公开了一种用于测量液体样品中分析物的传感器和分析仪。 传感器包括其中设置有储存器的基板。 储存器可以包括顶表面和底表面，形成储存器的底表面的至少一部分的至少一个透明部分，以及设置在储存器的上表面上的反射器，该反射器位于与至少一个透明 一部分。 分析器可以包括支撑表面，延伸穿过支撑表面的孔，设置在支撑表面下方并且被定向成使得从光源发射的光的至少一部分穿过孔的光源，以及检测器，被配置为 测量在检测器处接收的光强度。
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公开(公告)号：US11035784B2
公开(公告)日：2021-06-15
申请号：US16679728
申请日：2019-11-11
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, Jr. , Gary Conrad Jensen
Abstract: A method for measuring hemoglobin concentration in a whole blood sample is disclosed. The method may include mixing a whole blood sample with a lysing agent, followed by manual agitation, flowing the whole blood or mixture into a reservoir of a sensor, the sensor comprising a transparent portion configured to allow an optical measurement of an absorbance or reflectance of the whole blood sample in the reservoir of the sensor; detecting, using an analyzer into which at least a portion of the sensor has been inserted, the whole blood sample in the reservoir of the sensor; upon detecting the liquid whole blood sample in the reservoir, optically measuring an absorbance or reflectance of the whole blood sample using a light source and a detector in the analyzer; and determining a concentration of hemoglobin in the whole blood sample based on the measured absorbance or reflectance and a calibration curve that relates the absorbance or reflectance to the concentration of hemoglobin in the whole blood sample.
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公开(公告)号：US10473582B2
公开(公告)日：2019-11-12
申请号：US15701006
申请日：2017-09-11
Applicant: Magellan Diagnostics, Inc.
Inventor： Norman F. Sheppard, Jr. , Gary Conrad Jensen
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
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