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公开(公告)号：US20190278972A1
公开(公告)日：2019-09-12
申请号：US16335169
申请日：2017-10-10
Applicant: OPTOS PLC , NIKON CORPORATION
Inventor： Alan ANDERSON , Praveen ASHOK , Tomoharu FUJIWARA , Yasushi TANABE , Hiroshi KINTOU , Mariko HIROKAWA , Tadashi UMEZAKI
Abstract: There is provided an ocular image capturing device comprising an ocular image generating module operable to generate an image of a subject's eye based on light reflected from the eye, and a determination module arranged to determine whether or not at least a portion of a pupil region of the generated image is within a predetermined permissible region within the generated image, and to generate a signal that is indicative of the determination, the pupil region being an image of at least a portion of the pupil of the eye.
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公开(公告)号：US10398310B2
公开(公告)日：2019-09-03
申请号：US15325020
申请日：2015-07-10
Applicant: Optos PLC
Inventor： Derek Swan , Gonzalo Muyo , Alistair Gorman
Abstract: An ophthalmoscope (1) and method for scanning a fundus (23) of an eye (9), comprising a light system (3) which produces linear light, a scanner (5) which receives at least some of the linear light and is movable about a scan axis to produce a 1D scan of the at least some linear light, and a scan transfer system (7) which receives the 1D scan from the scanner and transfers the 1D scan to the eye, wherein the scanner is positioned in the ophthalmoscope such that it receives the at least some of the linear light substantially along the scan axis, the scan transfer system positioned in the ophthalmoscope such that a pupil of the eye is provided at a focal point of the system, and the scanner is positioned in the ophthalmoscope and the scan transfer system is configured to transfer the 1D scan from the scanner through the focal point at the eye pupil and onto the eye fundus.
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公开(公告)号：US10349825B2
公开(公告)日：2019-07-16
申请号：US15308028
申请日：2015-05-01
Applicant: Optos PLC
Inventor： Jano van Hemert , Michael Verhoek , David Brown , Charles Wykoff , Daniel Croft
Abstract: A method of determining a measurement of at least one cell type in an eye, comprising (i) obtaining a map of the cell type in the eye, (ii) obtaining a representation of the retina of the eye, (iii) matching the eye cell type map to the representation of the retina of the eye, (iv) defining a region of interest on the representation of the retina of the eye, (v) calculating a size of the region of interest on the representation of the retina of the eye, (vi) using the matched eye cell type map and the size of the region of interest to determine a measure of the cell type in the region of interest of the retina of the eye.
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公开(公告)号：US10149612B2
公开(公告)日：2018-12-11
申请号：US14267645
申请日：2014-05-01
Applicant: Optos PLC
Inventor： Gonzalo Muyo , Derek Swan
Abstract: A scanning laser ophthalmoscope for scanning the retina of an eye is provided comprising a light source emitting a beam of light, scan relay elements, wherein the light source and the scan relay elements provide a two-dimensional scan of the light beam which is transferred from an apparent point source at a pupillary point of the eye to the retina of the eye, and a static aberration correction element which has a shape defined to provide correction of aberrations of at least some of the scan relay elements and a location within the ophthalmoscope chosen to provide correction of aberrations of at least some of the scan relay elements, which location maintains transfer of the beam of light from the apparent point source at the pupillary point of the eye to the retina of the eye.
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公开(公告)号：US09788717B2
公开(公告)日：2017-10-17
申请号：US15013504
申请日：2016-02-02
Applicant: Optos PLC
Inventor： Hind Azegrouz
CPC classification number: A61B3/1025 , A61B3/0025 , A61B3/12 , G02B26/127
Abstract: A method of reducing jitter error in a laser scanning system adapted to produce a scanned image including a number of lines of an object. The method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.
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Patent Agency Ranking
公开(公告)号：US20170202457A1
公开(公告)日：2017-07-20
申请号：US15325020
申请日：2015-07-10
Applicant: Optos PLC
Inventor： Derek Swan , Gonzalo Muyo , Alistair Gorman
CPC classification number: A61B3/12 , A61B3/1025 , G02B26/105
Abstract: An ophthalmoscope (1) and method for scanning a fundus (23) of an eye (9), comprising a light system (3) which produces linear light, a scanner (5) which receives at least some of the linear light and is movable about a scan axis to produce a 1D scan of the at least some linear light, and a scan transfer system (7) which receives the 1D scan from the scanner and transfers the 1D scan to the eye, wherein the scanner is positioned in the ophthalmoscope such that it receives the at least some of the linear light substantially along the scan axis, the scan transfer system positioned in the ophthalmoscope such that a pupil of the eye is provided at a focal point of the system, and the scanner is positioned in the ophthalmoscope and the scan transfer system is configured to transfer the 1D scan from the scanner through the focal point at the eye pupil and onto the eye fundus.
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公开(公告)号：US09649031B2
公开(公告)日：2017-05-16
申请号：US14267642
申请日：2014-05-01
Applicant: Optos PLC
Inventor： Jano Van Hemert , Michael Verhoek
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/1025 , A61B3/12 , A61B3/14 , G06T7/0012 , G06T7/64 , G06T2207/30041
Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).
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公开(公告)号：US20170032502A1
公开(公告)日：2017-02-02
申请号：US15222728
申请日：2016-07-28
Applicant: Optos PLC
Inventor： Jano van Hemert , Alan Fleming , David Clifton
IPC: G06T5/00
Abstract: The present disclosure provides a method of processing an image comprising receiving a measured image, producing a sharpened image by filtering the measured image to increase its sharpness, and transforming the sharpened image using at least one selected geometric transformation. The present disclosure further provides a computer readable media storing program instructions which, when executed, perform the method of processing an image and a system for processing an image comprising a receiving module which receives a measured image, a sharpening module which produces a sharpened image by filtering the measured image to increase its sharpness, and a transformation module which transforms the sharpened image using at least one selected geometric transformation.
Abstract translation: 本公开提供了一种处理图像的方法，包括接收测量图像，通过对所测量的图像进行滤波来提高其锐度，并使用至少一个选择的几何变换来变换锐利图像来产生锐化图像。 本公开还提供了一种存储程序指令的计算机可读介质，所述程序指令在被执行时执行处理图像的方法和用于处理包括接收测量图像的接收模块的图像的系统，所述锐化模块通过 过滤测量的图像以增加其清晰度;以及变换模块，其使用至少一个选择的几何变换来转换锐化的图像。
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公开(公告)号：US09454817B2
公开(公告)日：2016-09-27
申请号：US14654249
申请日：2014-02-19
Applicant: Optos PLC
Inventor： David Clifton , Ralph Allen Pinnock
CPC classification number: G06T7/003 , A61B3/0025 , A61B3/1225 , G06T5/20 , G06T7/136 , G06T7/32 , G06T7/337 , G06T2207/20164 , G06T2207/30041 , G06T2207/30101
Abstract: An image processing apparatus uses first and second digital vascular image data to register two images. The two images may be from different imaging modes. The first and second images are processed with a two-dimensional, directional filter (500) that has the effect of producing clusters of orthogonally adjacent image data points in which the magnitude of an intensity gradient between each orthogonally adjacent image data point is less than a predetermined value. Subsequently, common clusters are identified between the first and second image data using a corner detecting algorithm (600). The directional filter produces “stepping” features, where vascular features would otherwise appear with smooth edges. These numerous features are identified by the corner detecting algorithm and can be used (1000) for registering common clusters between the first and second image data. The filter may be a rotating Gabor filter matched to vascular features in the images.
Abstract translation: 图像处理装置使用第一和第二数字血管图像数据来登记两个图像。 两个图像可以来自不同的成像模式。 第一和第二图像用二维方向滤波器（500）处理，其具有产生正交相邻图像数据点的聚类的效果，其中每个正交相邻图像数据点之间的强度梯度的幅度小于 预定值。 随后，使用角部检测算法（600）在第一和第二图像数据之间识别公共集群。 方向滤波器产生“步进”特征，其中血管特征将以平滑的边缘出现。 这些许多特征由角部检测算法识别，并且可以使用（1000）来注册第一和第二图像数据之间的公共簇。 滤波器可以是与图像中的血管特征匹配的旋转Gabor滤波器。
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公开(公告)号：US12256990B2
公开(公告)日：2025-03-25
申请号：US17702119
申请日：2022-03-23
Applicant: OPTOS PLC
Inventor： Alan Duncan Fleming
Abstract: There is provided a method of processing image data defining a fundus image of a retina to include supplementary information on a designated feature in the fundus image, comprising: designating (S10) a feature in the fundus image; receiving (S20) OCT data of a C-scan of the retina; selecting (S30) a subset of the OCT data representing a volumetric image of a part of the retina at a location on the retina corresponding to a location of the designated feature in the fundus image; processing (S40) the selected subset to generate, as the supplementary information, supplementary image data indicative of a variation, along a depth direction of the retina, of a measured reflectance of the eye in the selected subset; and combining (S50) the image data with the supplementary image data, such that an image defined by the combined data provides an indication of the variation at the designated feature.
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