公开(公告)号：US10271557B2

公开(公告)日：2019-04-30

申请号：US14974437

申请日：2015-12-18

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Linda V Thomas ,  Richard Ingram ,  Torben Isak ,  Bob Coyne ,  John Faragher ,  Sebastien Gouin ,  Carsten Bjoern Hansen ,  Kathryn Louise Tse

IPC: A01N65/22 ,  A21D2/00 ,  A23B4/10 ,  A23B4/12 ,  A23B4/20 ,  A23B4/22 ,  A23B5/06 ,  A23B5/14 ,  A23B5/16 ,  A23C19/084 ,  A23C19/11 ,  A23L2/52 ,  A23L3/3463 ,  A23L3/3472 ,  A23L3/3544 ,  A23L3/3571 ,  B01J13/04 ,  B01J13/08 ,  B01J13/14 ,  B01J13/22 ,  A01N31/08 ,  A01N35/06 ,  A01N37/36 ,  A01N37/38 ,  A01N37/46 ,  A01N25/28 ,  A23P10/30 ,  A23P10/35 ,  A23L33/10 ,  A23L33/135 ,  A23L13/70

Abstract: The present invention provides a composition comprising (a) an antimicrobial material; and (b) an extract obtained from or obtainable from a plant of the Labiatae family, wherein (a) and (b) are different; wherein the composition contains phenolic diterpenes in an amount of greater than 1.0 wt. %, based on the composition, and wherein when the antimicrobial material consists of nisin, the composition comprises carvacrol in an amount of less than 0.075 wt. % based on the composition and carvone in an amount of less than 15 wt. % based on the composition.

公开(公告)号：US10137090B2

公开(公告)日：2018-11-27

申请号：US15378332

申请日：2016-12-14

Applicant: METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE

Inventor： Cheng-Han Hung ,  Zong-Hsin Liu ,  Ying-Chieh Lin ,  Ming-Fang Tsai ,  Hai-Ching Tsou ,  Ying-Cheng Lu

IPC: A61K9/16 ,  B01J2/06 ,  B01J2/18 ,  B01J13/08 ,  B01J13/20

Abstract: A nozzle, an apparatus, and a method for producing dual-layer microparticles used as microcarriers. The nozzle includes a nozzle body having a first fluid passageway and a cover mounted to the nozzle body and having a second fluid passageway. A plurality of extension tubes is communicated with an end of the first fluid passageway and is spaced from each other. Each extension tube includes an outlet port distant to the first fluid passageway. A plurality of sleeves is communicated with the second fluid passageway. Each sleeve includes an opening distant to the second fluid passageway. Each extension tube extends into one of the sleeves. An outer wall of each extension tube is spaced from an inner wall of one of the sleeves. The outlet port of each extension tube is located between the second fluid passageway and the opening of one of the sleeves.

公开(公告)号：US20180323436A1

公开(公告)日：2018-11-08

申请号：US15968654

申请日：2018-05-01

Applicant: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED

Inventor： Yujun CHEN ,  Xinliang KUANG ,  Long WANG ,  Na LIU ,  Huan NI

IPC: H01M4/62 ,  H01M4/36 ,  H01M4/525 ,  H01M4/505 ,  B01J13/08 ,  H01M10/0525

CPC classification number: H01M4/628 ,  B01J13/08 ,  H01M4/0404 ,  H01M4/0471 ,  H01M4/131 ,  H01M4/1391 ,  H01M4/366 ,  H01M4/505 ,  H01M4/525 ,  H01M4/622 ,  H01M4/624 ,  H01M10/0525 ,  H01M2004/028

Abstract: The present disclosure provides a modified positive electrode active material. The modified positive electrode active material comprises a positive electrode active material inner core; a metal oxide layer comprising a metal oxide and coated on a surface of the positive electrode active material inner core; and a polymer layer comprising a polymer and coated on a surface of the metal oxide layer, the polymer being one or more selected from a group consisting of polyacrylic acid, polymethyl methacrylate, polyacrylamide and lithium polyacrylate. The modified positive electrode active material of the present disclosure has better structure stability and thermal stability, when the modified positive electrode active material is applied in the electrochemical energy storage device, cycle performance and safety performance of the electrochemical energy storage device can be significantly improved without decreasing energy density of the electrochemical energy storage device.

公开(公告)号：US20180010013A1

公开(公告)日：2018-01-11

申请号：US15646478

申请日：2017-07-11

Applicant: Microtek Laboratories, Inc.

Inventor： Carl M. LENTZ ,  Kayla L. M. RYAN

IPC: C09F9/00 ,  B01J13/08 ,  B01J13/22 ,  C09D5/00

CPC classification number: C09D5/14 ,  A01N25/28 ,  A01N59/06 ,  A01N59/16 ,  A01N59/20 ,  A01N59/26 ,  B01J13/02 ,  B01J13/08 ,  B01J13/14 ,  B01J13/22 ,  C08G14/08 ,  C09D5/00 ,  C09D7/61 ,  C09D7/66 ,  C09D133/00 ,  C09D161/28 ,  C09D161/34 ,  C09D179/04 ,  C09F9/00 ,  C09K5/063 ,  F28D20/023 ,  Y02E60/145

Abstract: Ruptureable, dual reagent mono-capsules are disclosed that have a core composition, which includes a first reagent, encapsulated within a polymer wall, and a shell connected to an exterior surface of the polymer wall by a surfactant. The shell is made from a second reagent that is chemically bonded to the surfactant by a chemical electrostatic interaction. Upon rupture of the polymer wall of the mono-capsule, the first reagent and the second reagent chemically react with one another to form a reaction product.

公开(公告)号：US20170281543A1

公开(公告)日：2017-10-05

申请号：US15625391

申请日：2017-06-16

Applicant: FUJIFILM Corporation

Inventor： Susumu SUGIYAMA ,  Naoki YAMADA ,  Shigehisa SUGIYAMA ,  Yohei OKUBO

IPC: A61K9/127 ,  B01F5/02 ,  B01F3/08 ,  B01F5/10 ,  A61K31/7068 ,  B01J13/08

CPC classification number: A61K9/1277 ,  A61K9/127 ,  A61K9/1271 ,  A61K31/7068 ,  B01F3/08 ,  B01F3/0807 ,  B01F5/0206 ,  B01F5/10 ,  B01F2215/0032 ,  B01J13/04 ,  B01J13/08 ,  B82Y5/00 ,  B82Y40/00

Abstract: Disclosed herein are a method for producing a miniaturized liposome on a large production scale, and an apparatus for producing a liposome which is to be used in the above-mentioned method. Provided is a method for producing a liposome, including a step of stirring a mixture containing an oil phase in which at least one lipid is dissolved in an organic solvent and a water phase in a first tank of an apparatus having the first tank and a circulation path, in which the ratio of the capacity of the circulation path to the total capacity of the tank and the circulation path is 0.4 or less and/or the time required for the mixture to return to the first tank after being discharged therefrom is within 2.0 minutes.

公开(公告)号：US20170233645A1

公开(公告)日：2017-08-17

申请号：US15584042

申请日：2017-05-02

Applicant: SHENZHEN TCL NEW TECHNOLOGY CO., LTD

Inventor： Haizheng Zhong ,  Feng Zhang ,  Xiangang Wu ,  Hailong Huang ,  Yuwei Niu

IPC: C09K11/06 ,  B01J13/08 ,  H01L51/00 ,  H01L51/50 ,  H01L51/52 ,  C09K11/02 ,  B01D17/04

CPC classification number: C09K11/06 ,  B01D17/047 ,  B01J13/08 ,  C09K11/02 ,  C09K11/025 ,  C09K11/61 ,  C09K11/66 ,  C09K11/664 ,  C09K11/75 ,  C09K11/87 ,  C09K2211/10 ,  C09K2211/188 ,  H01L33/50 ,  H01L51/0003 ,  H01L51/0077 ,  H01L51/502 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5206 ,  H01L51/5234 ,  H01L2251/301 ,  H01L2251/308

Abstract: Provided is a hybridized perovskite quantum dot material. The quantum dot material comprises a kernel and surface ligands. The kernel is formed by R1NH3AB3 or (R2NH3)2AB4, where R1 is methyl group, R2 is an organic molecular group, A is at least one selected from Ge, Sn, Pb, Sb, Bi, Cu and Mn, B is at least one selected from Cl, Br and I, A and B form a coordination octahedral structure, and R1NH3 or R2NH3 is filled in gaps of the coordination octahedral structure. The surface ligand is an organic acid or organic amine. The quantum dot material has a high fluorescence quantum yield.

公开(公告)号：US20170202776A1

公开(公告)日：2017-07-20

申请号：US15429113

申请日：2017-02-09

Applicant: ZONEONE PHARMA, INC.

Inventor： Mark E. HAYES ,  Charles O. NOBLE ,  Francis C. SZOKA, JR.

IPC: A61K9/127 ,  B01J13/08 ,  A61K31/496 ,  A61K31/4196 ,  A61K38/07 ,  A61K9/00

CPC classification number: A61K9/1278 ,  A61K9/0019 ,  A61K9/1271 ,  A61K9/1275 ,  A61K9/19 ,  A61K31/4196 ,  A61K31/496 ,  A61K31/5377 ,  A61K38/07 ,  B01J13/08

Abstract: The present invention provides liposome compositions containing sparingly soluble drugs that are used to treat life-threatening diseases. A preferred method of encapsulating a drug inside a liposome is by remote or active loading. Remote loading of a drug into liposomes containing a transmembrane electrochemical gradient is initiated by co-mixing a liposome suspension with a solution of drug, whereby the neutral form of the compound freely enters the liposome and becomes electrostatically charged thereby preventing the reverse transfer out of the liposome. There is a continuous build-up of compound within the liposome interior until the electrochemical gradient is dissipated or all the drug is encapsulated in the liposome. However, this process as described in the literature has been limited to drugs that are freely soluble in aqueous solution or solubilized as a water-soluble complex. This invention describes compositions and methods for remote loading drugs with low water solubility (

公开(公告)号：US20170202756A1

公开(公告)日：2017-07-20

申请号：US15327732

申请日：2015-07-20

Applicant: SATISLOH AG

Inventor： Mamonjy Cadet ,  Camille Meridiano ,  Hervé HUILIER ,  Adeline Callet

IPC: A61K8/11 ,  A61K8/42 ,  A01N25/28 ,  A61Q17/02 ,  A61Q17/00 ,  C11D11/00 ,  B01J13/04 ,  B01J13/18 ,  B01J13/08 ,  B01J13/22 ,  C11D17/04 ,  A61K8/02 ,  A01N25/08

CPC classification number: A61K8/11 ,  A01N25/08 ,  A01N25/28 ,  A61K8/0208 ,  A61K8/42 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/624 ,  A61Q17/005 ,  A61Q17/02 ,  A61Q19/00 ,  B01J13/043 ,  B01J13/08 ,  B01J13/18 ,  B01J13/22 ,  C11D11/0035 ,  C11D17/0039 ,  C11D17/049 ,  D06M23/12 ,  A01N37/46

Abstract: The invention relates to a support consisting of natural and/or synthetic fibres which particles are held, which are preferably water-soluble, comprising at least one active agent, said particles at least partially releasing the active agent(s) under the effect of an external stress, characterised in the active agent has a water-solubility of between 0.1 and 60 wt. %, preferably between 0.1 and 30 wt. %.

公开(公告)号：US20170189569A1

公开(公告)日：2017-07-06

申请号：US15460708

申请日：2017-03-16

Applicant: Omid Souresrafil ,  Ehson Souresrafil ,  Nazmi Peyman

Inventor： Omid Souresrafil ,  Ehson Souresrafil ,  Nazmi Peyman

IPC: A61K51/12 ,  B01J13/08 ,  A61K51/06

CPC classification number: A61K51/1251 ,  B01J13/06 ,  B01J13/08 ,  B01J13/14 ,  B01J13/206

Abstract: A crosslinked NATURAL POLYMER POLYMER/NATURAL POLYMER POLYMER microsphere comprising a stably incorporated radionuclide. The microsphere can be prepared by droplet microfluidics and used in a method for radiation treatment comprising the administration of microspheres with incorporated radionuclide.

公开(公告)号：US20170125800A1

公开(公告)日：2017-05-04

申请号：US15317405

申请日：2015-06-05

Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS, CHINESE ACADEMY OF SCIENCE

Inventor： Yuegang ZHANG ,  Yongcai QIU ,  Wanfei LI ,  Guizhu LI ,  Yuan HOU ,  Meinan LIU ,  Lisha ZHOU ,  Fangmin YE ,  Hongfei LI

IPC: H01M4/36 ,  H01M4/58 ,  B01J13/08 ,  H01M4/587

CPC classification number: H01M4/366 ,  B01J13/08 ,  H01M4/38 ,  H01M4/5815 ,  H01M4/587 ,  H01M4/625 ,  H01M2004/028

Abstract: The invention provides a nitrogen-doped graphene coated nano sulfur positive electrode composite material, a preparation method, and an application thereof. The composite material includes: an effective three-dimensional conductive network formed by overlapping of nitrogen-doped graphenes, and nano sulfur particles coated by nitrogen doped graphene layers evenly. The preparation method includes: dispersing nitrogen-doped graphenes in a liquid-phase reaction system including at least sulfur source and acid, and depositing nano sulfur particles by an in-situ chemical reaction of the sulfur source and the acid, thereby preparing the positive electrode composite material. The positive electrode composite material of the invention has a high conductivity, a high sulfur utilization rate, and a high rate, thereby restraining the dissolution and shuttle effect in the lithium sulfur batteries, and enhancing the cyclic performance of the batteries.