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公开(公告)号：US11835626B2
公开(公告)日：2023-12-05
申请号：US17948026
申请日：2022-09-19
Inventor： Duhyun Lee , Muhammad Alam , Harry Atwater , Ragip Pala , Byunghoon Na , Seunghoon Han
CPC classification number: G01S17/02 , G01S7/481 , G01S7/4817 , G02F1/01716 , G02F1/21 , G02F1/292 , G02F1/0151 , G02F1/213 , G02F2202/30
Abstract: Provided are an optical modulating device and a system including the optical modulating device. The optical modulating device includes a substrate, and a phase modulator formed on the substrate and including a Fabry-Perot cavity. The Fabry-Perot cavity of the phase modulator includes a first reflective layer, a second reflective layer, and a tunable core formed between the first reflective layer and the second reflective layer, wherein the tunable core is formed of a semiconductor material and is configured to modulate a phase of light corresponding to modulation of a refractive index of the tunable core according to electrical control.
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公开(公告)号：US11831183B2
公开(公告)日：2023-11-28
申请号：US17122390
申请日：2020-12-15
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Mahshid Roumi , Farshid Roumi
CPC classification number: H02J7/00 , H02J7/0013 , H02J7/00714 , H02J13/00002 , H02J7/0025 , H02J7/00034 , H02J13/00001 , H02J2207/40 , Y02T10/70
Abstract: A plurality of battery packs is provided in communication with an energy monitoring and control system. Each battery pack includes a plurality of battery cells that collectively dictate the capabilities of the battery pack. The energy monitoring and control system determines a plurality of pack charging or pack discharging parameters for each battery pack that, when performed, achieve one or more performance metrics at a user level (e.g., performance metrics of each battery pack within a system of multiple battery packs). The battery pack further determines a plurality of cell charging or cell discharging parameters for each battery cell based upon the determined plurality of pack charging or pack discharging parameters for each battery cell that, when performed, achieve one or more performance metrics at a battery level (e.g., performance metrics of different cells of each battery pack).
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公开(公告)号：US11824248B2
公开(公告)日：2023-11-21
申请号：US17127605
申请日：2020-12-18
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Oskar Painter , Seyed Mohammad Mirhosseini Niri , Eun Jong Kim , Alp Sipahigil , Vinicius Thaddeu dos Santos Ferreira , Andrew J. Keller , Mahmoud Kalaee , Michael T. Fang
CPC classification number: H01P3/00 , G06N10/00 , G02F2202/30
Abstract: A shielded bridge for a coplanar waveguide (CPW) includes a signal bridge extending from a first terminal of the CPW to a second terminal of the CPW. The signal bridge has a raised central portion that extends over a separate signal conductor. The shielded bridge for the CPW also includes a ground bridge extending from a first ground plane on a first side of the separate signal conductor to a second ground plane on a second side of the separate signal conductor. The ground bridge is positioned between the signal bridge and the separate signal conductor.
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104.发明授权公开(公告)号：US11820973B2
公开(公告)日：2023-11-21
申请号：US16885131
申请日：2020-05-27
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Dianne K. Newman , Ryan C. Hunter
Abstract: Provided herein are methods and systems for interfering with viability of bacteria and related compounds and compositions.
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公开(公告)号：US20230363672A1
公开(公告)日：2023-11-16
申请号：US18319085
申请日：2023-05-17
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Samson CHEN , Axel SCHERER , Dvin I. ADALIAN , Peter PETILLO , Muhammad Musab JILANI , Xiomara L. MADERO , Deepan KISHORE KUMAR
IPC: A61B5/1486 , C12N11/14 , A61B5/145 , A61B5/1459 , G01N27/327 , C12N9/02 , C12N11/02
CPC classification number: A61B5/14865 , A61B5/14532 , A61B5/1459 , C12N9/0004 , C12N11/02 , C12N11/14 , G01N27/3272 , C12Y101/01001 , C12Y101/03003 , C12Y101/03005 , C12Y101/03007 , C12Y101/03008 , C12Y101/0301 , C12Y101/03011 , C12Y101/03012 , C12Y101/03015 , C12Y101/03016 , C12Y101/03018 , C12Y101/03019 , C12Y101/0302 , C12Y101/03023 , C12Y101/03027 , C12Y101/03029 , C12Y101/0303 , C12Y101/03037 , C12Y101/03038 , C12Y101/0304 , C12Y101/03041
Abstract: A sensor implanted in tissues and including a sensing layer is fabricated by mixing the signal transduction enzyme with non-reactive components including buffer salts and fillers, and spin coating the enzyme onto a substrate. The signal transduction enzyme is crosslinked by introducing the coated substrate in a vacuum chamber. In the chamber, a crosslinker evaporates and is deposited onto the enzyme, therefore crosslinking the enzyme.
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Patent Agency Ranking
106.发明公开公开(公告)号：US20230358677A1
公开(公告)日：2023-11-09
申请号：US18303528
申请日：2023-04-19
Inventor： Annette Boehme , Alexandra J. Welch , Rohit Bhide , Cassidy Feltenberger , Shane Ardo , Harry A. Atwater , Dennis Tang
CPC classification number: G01N21/6428 , G01N21/80 , G01N2021/6441 , G01N2021/6443
Abstract: Systems and methods for sensing and measuring local pH, pOH, and other protonic species using reversible excited-state photoacids and photobases are described. Various reversible excited-state photoacids and/or photobases are described that through a dynamic sensing mechanism exhibit varied fluorescence or phosphorescence intensity based on local activity of protonic species. Photoacids and photobases can be used in combination with confocal fluorescent microscopy for quantifying local activity of protonic species.
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公开(公告)号：US20230357434A1
公开(公告)日：2023-11-09
申请号：US18177566
申请日：2023-03-02
Applicant: California Institute of Technology
Inventor： Timothy F. Shay , Viviana Gradinaru , Xiaozhe Ding
CPC classification number: C07K16/40 , C12N15/86 , A61P25/00 , C12N2750/14143 , C07K2317/31
Abstract: Disclosed herein include novel blood-brain barrier (BBB)-crossing receptors on the BBB interface, targeting peptides and derivatives thereof capable of binding to the novel receptors, and related methods of using the receptors to increase the permeability of the BBB and to deliver an agent to a nervous system (e.g., CNS). In some embodiments, the BBB-crossing receptor is carbonic anhydrase IV. Disclosed herein also include recombinant adeno-associated viruses (rAAVs) with increased specificity and transduction efficiency across the BBB and related compositions and methods of treating various diseases and conditions.
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108.发明授权公开(公告)号：US11807617B2
公开(公告)日：2023-11-07
申请号：US17336756
申请日：2021-06-02
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Tonia S. Ahmed , Robert H. Grubbs
IPC: C07D313/00 , B01J31/22
CPC classification number: C07D313/00 , B01J31/226 , B01J31/2273 , B01J31/2291 , B01J2231/543 , B01J2531/821
Abstract: A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z).
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公开(公告)号：US20230346886A1
公开(公告)日：2023-11-02
申请号：US18076786
申请日：2022-12-07
Applicant: California Institute of Technology , The Regents of the University of California , U.S. Government represented by the Department of Veterans Affairs
Inventor： Robert H. Grubbs , Daniel M. Schwartz
CPC classification number: A61K38/1891 , A61B3/102 , A61B3/1241 , A61K9/0048 , A61K38/1866 , A61P27/02
Abstract: Disclosed herein include methods, kits, formulations, and compositions for increasing choroidal or retinal perfusion or promoting non-leaking or minimally-leaking choroidal or retinal revascularization in a subject in need thereof. An effective amount of an angiogenesis factor (e.g., a pro-angiogenic factor and/or a vascular maturation factor) can be administered to the subject.
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公开(公告)号：US20230330942A1
公开(公告)日：2023-10-19
申请号：US18302598
申请日：2023-04-18
Applicant: California Institute of Technology
Inventor： Scott N. Roberts , Mauricio Zuleta
IPC: B29C64/40 , B29C64/245 , B29C64/393 , B33Y80/00 , B33Y50/02
CPC classification number: B29C64/40 , B29C64/245 , B29C64/393 , B33Y80/00 , B33Y50/02
Abstract: A process may obtain a design for an erodible support structure and a part. A process may use an additive manufacturing process to manufacture the part and the erodible support structure, wherein the erodible support structure is configured to mechanically support the part during the additive manufacturing process, and wherein the erodible support structure has elevated porosity compared to the part and is erodible by mechanical and chemical means.
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