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    Fluid Interface to Receive Removable Container
    111.
    发明申请
    Fluid Interface to Receive Removable Container 有权

    公开(公告)号：US20220185653A1

    公开(公告)日：2022-06-16

    申请号：US17559440

    申请日：2021-12-22

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Todd ROSWECH ,  Jonathan SCHULTZ ,  Chun HO

    IPC: B67D7/02 ,  B67D7/76 ,  B01L3/00

    Abstract: A fluidic interconnect includes a first interface including a liquid port, a gas port, and a cradle; a second interface including a liquid port, a gas port, and a swing bar to engage the cradle, a weight of a container attached to one of the first or second interfaces to drive the liquid port of the first interface into connection with the liquid port of the second interface and the gas port of the first interface into connection with the gas port of the second interface.

    Cell Settler Apparatus Systems and Methods for Perfusion Processes
    114.
    发明申请
    Cell Settler Apparatus Systems and Methods for Perfusion Processes 有权

    公开(公告)号：US20220145230A1

    公开(公告)日：2022-05-12

    申请号：US17609351

    申请日：2020-05-13

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Stephan KAISER

    IPC: C12M1/00 ,  C12M1/26 ,  C12M1/04 ,  C12M1/34

    Abstract: The present set of embodiments relate to a system, method, and apparatus for separating cells from a suspension using a gravity driven cell separation device. The apparatus may include a chamber that is separated into a gas compartment and a liquid compartment allowing for transfer of gas through a membrane into the liquid compartment where the cell suspension flows during operation. The embodiments are designed to maximize the gravitational separation effect on the suspension while mitigating the loss of surface area through which gas transfer can occur through a membrane to provide nutrients to cells in the suspension by tilting the cell separation device on two or more axes.

    SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING
    119.
    发明申请
    SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING 有权

    公开(公告)号：US20220072681A1

    公开(公告)日：2022-03-10

    申请号：US17478096

    申请日：2021-09-17

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Yerramalli Subramaniam ,  Puneet Suri ,  Sylvia Chang ,  Chengyong Yang

    IPC: B24B41/06 ,  G16B30/00 ,  G05B11/01 ,  B24B5/04

    Abstract: Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc.

    Device, System and Method for Fluid Delivery for Sequencing
    120.
    发明申请
    Device, System and Method for Fluid Delivery for Sequencing 有权

    公开(公告)号：US20220065890A1

    公开(公告)日：2022-03-03

    申请号：US17524840

    申请日：2021-11-12

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Albert L. Carrillo ,  John Donohue

    IPC: G01N35/10 ,  G01N35/00 ,  B01L3/00

    Abstract: Various embodiments of a fluidic system of the present teachings are configured to execute a sequence of fluidic operations over the course of a next generation sequencing analysis for the sequential delivery of various solutions used over the course of analysis to a multilane sensor device. Exemplary fluidic operations include washing, priming and nucleotide reagent delivery through a fluidic multiplexer block that is configured to provide independent fluid distribution to each lane of a multilane sensor device used for detection during an analysis. Accordingly, any number or combination of lanes can be used during an analysis, so that during an analysis one lane in any position can be used singly during a run, all four lanes can be used simultaneously during a run, or any combination of lanes can be used simultaneously during a run.

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