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公开(公告)号:US10689730B2
公开(公告)日:2020-06-23
申请号:US14935245
申请日:2015-11-06
Applicant: University of Utah Research Foundation
Inventor: Zhigang Zak Fang , Ying Zhang , Yang Xia , Pei Sun
Abstract: A method (500) for producing a titanium product is disclosed. The method (500) can include obtaining TiO2-slag (501) and reducing impurities in the TiO2-slag (502) to form purified TiO2 (503). The method (500) can also include reducing the purified TiO2 using a metallic reducing agent (504) to form a hydrogenated titanium product comprising TiH2 (505). The hydrogenated titanium product can be dehydrogenated (506) to form a titanium product (508). The titanium product can also be optionally deoxygenated (507) to reduce oxygen content.
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公开(公告)号:US20200183243A1
公开(公告)日:2020-06-11
申请号:US16319432
申请日:2017-07-20
Applicant: University of Utah Research Foundation
Inventor: Logan Kiefer , Max Gallant , Nicholas Flinner , Christian Robert , Thomas Folke , Taylor D. Sparks
IPC: G02F1/1503 , G02F1/155 , C09K9/02 , C09B57/00 , C08F20/14 , C08K5/13 , C08K5/3432 , A61F9/02 , A42B3/22 , E06B9/24
Abstract: An active electrochromic film (500) can include a transparent flexible substrate (510), a first transparent electrically conductive layer (520) in contact with the transparent flexible substrate (510), an active electrochromic gel layer (530) in contact with the transparent electrically conductive layer (520), and a second transparent electrically conductive layer (515) in contact with the active electrochromic gel layer (530) opposite from the first transparent electrically conductive layer (520). The active electrochromic gel layer (530) can include a viologen-based compound. The active electrochromic gel layer (530) can exhibit a high visible optical transparency in the absence of a voltage applied across the first and second transparent electrically conductive layers (520,515) and a low visible optical transparency under an applied voltage. In one example, at least one of the first and second transparent electrically conductive layers (520,515) can include a masked portion (580) such that the active electrochromic gel layer (530) is insulated from the applied voltage in an area adjacent to the masked portion (580).
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公开(公告)号:US10655169B2
公开(公告)日:2020-05-19
申请号:US15491916
申请日:2017-04-19
Inventor: Luming Zhou , Carl T. Wittwer , Philip Seth Bernard , Virginie Dujols
IPC: C12P19/34 , C12Q1/6851 , C12Q1/6883 , C09B23/04 , C12Q1/6813
Abstract: Methods are provided for nucleic acid analysis wherein a target nucleic acid is mixed with a dsDNA binding dye to form a mixture. Optionally, an unlabeled probe is included in the mixture. A melting curve is generated for the target nucleic acid by measuring fluorescence from the dsDNA binding dye as the mixture is heated. Dyes for use in nucleic acid analysis and methods for making dyes are also provided.
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公开(公告)号:US10653813B2
公开(公告)日:2020-05-19
申请号:US15833157
申请日:2017-12-06
Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
Inventor: Russell J. Stewart
IPC: A61L24/00 , A61L24/02 , A61L24/04 , A61L24/06 , A61L24/10 , A61L27/26 , A61L27/54 , C08F8/00 , C08F8/06
Abstract: Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. The adhesive complex coacervates described herein can be subsequently cured to produce strong, cohesive adhesives. The reinforced adhesive complex coacervates have several desirable features when compared to conventional adhesives. The reinforced adhesive complex coacervates are effective in wet or underwater applications. The reinforced adhesive complex coacervates described herein, being phase separated from water, can be applied underwater without dissolving or dispersing into the water. The reinforced adhesive complex coacervates have numerous biological applications as bioadhesives and bioactive delivery devices. In particular, the reinforced adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, wet tissues in physiological conditions.
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公开(公告)号:US10653371B2
公开(公告)日:2020-05-19
申请号:US14848102
申请日:2015-09-08
Applicant: University of Utah Research Foundation
Inventor: Dominic Heuscher , Frederic Noo
Abstract: A collimator for a computed tomography imaging device can include first and second leaves positioned on opposing sides of a primary radiation delivery window. The first and second leaves can include first and second gratings having a plurality of attenuating members with a plurality of secondary radiation delivery windows extending between adjacent attenuating members.
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116.
公开(公告)号:US20200088733A1
公开(公告)日:2020-03-19
申请号:US16658937
申请日:2019-10-21
Applicant: University of Utah Research Foundation
Inventor: Sean J. Mulvihill , Matthew A. Firpo
IPC: G01N33/574
Abstract: The present invention provides biomarker compositions and methods for the diagnosis and prognosis of PDAC. In a particular embodiment, the invention provides methods and compositions for screening, diagnosis and prognosis of early stage, asymptomatic PDAC.
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公开(公告)号:US10588761B2
公开(公告)日:2020-03-17
申请号:US15835954
申请日:2017-12-08
Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
Inventor: Brian Mueller Holt , Sujee Jeyapalina , Roy Drake Bloebaum , Kent Nelson Bachus
Abstract: An abutment system for operatively coupling an implant stem to an exo-prosthesis. The abutment system includes a plurality of interlocking sleeve elements that are operatively coupled to an implant stem positioned within a prepared site of a selected bone. The interlocking sleeve elements of the abutment system are selectively removable and replaceable.
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公开(公告)号:US20200080978A1
公开(公告)日:2020-03-12
申请号:US16573680
申请日:2019-09-17
Applicant: University of Utah Research Foundation
Inventor: Ling Zang , Benjamin Bunes , Miao Xu
Abstract: A multimode gas sensor platform can comprise an array of electrode pairs oriented on a substrate and a plurality of detection zones, wherein at least a portion of individual electrode pairs are separately addressable. Each detection zone can comprise at least one set of individual electrode pairs within the array, where the individual electrode pairs have organic nanofibers uniformly deposited thereon. The organic nanofibers can be responsive to association with a corresponding target material and at least one detection zone can be electronically responsive to the corresponding target material.
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119.
公开(公告)号:US20200071172A1
公开(公告)日:2020-03-05
申请号:US16294872
申请日:2019-03-06
Applicant: University of Utah Research Foundation
Inventor: Seyyed Pouya Hadipour Moghaddam , Hamidreza Ghandehari
IPC: C01B33/18
Abstract: The disclosure extends to biodegradable hollow nanoparticles, and systems, methods, devices, and processes for producing the same. The disclosure includes a method of preparing a hollow mesoporous nanoparticle by providing a plurality of silica core particles. Each of the plurality of silica core particles comprises a diameter within a range of about 600 nanometers to about 30 nanometers. The method further includes synthesizing a mesoporous silica shell around the plurality of silica core particles forming a plurality of mesoporous coated silica core particles. Further, the method provides for etching the plurality of mesoporous coated silica core particles with an aqueous solution of sodium carbonate and water to remove the silica core particle from the plurality of mesoporous coated silica core particles forming a plurality of hollow mesoporous particles. The method also includes diffusing a payload into the plurality of hollow mesoporous particles in an aqueous solution.
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120.
公开(公告)号:US20200069442A1
公开(公告)日:2020-03-05
申请号:US16610938
申请日:2018-05-09
Applicant: University of Utah Research Foundation
Inventor: Alex Drew , Kent Bachus , Erik Kubiak , Robert Tashjian , Heath Henniger
Abstract: An implant assembly for a long bone having a longitudinal axis. The implant assembly has a stem that is received in a surgically prepared medullary canal of the long bone. The stem defines at least one transverse through-opening that extends through the stem from a first portion of the outer surface of the stem to an opposed second portion of the outer surface of the stem. Each transverse through-opening has a central axis that is substantially perpendicular to the longitudinal axis of the stem. Each transverse through-opening receives a fastener and has a longitudinal dimension, measured relative to the longitudinal axis of the stem, that is sufficient to permit axial movement, relative to the longitudinal axis of the stem, of the stem relative to each fastener.
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