公开(公告)号：US20170196243A1

公开(公告)日：2017-07-13

申请号：US15313738

申请日：2015-06-03

Applicant: ABBOTT LABORATORIES

Inventor： JEFFREY BAXTER ,  RACHEL BLUMBERG ,  TIMOTHY CHAPMAN ,  NORMANELLA DEWILLE ,  KELLEY LOWE ,  GAURAV PATEL ,  DOUGLAS WEARLY

IPC: A23L2/66 ,  A23L33/19 ,  A23L33/185

CPC classification number: A23L2/66 ,  A23L33/185 ,  A23L33/19 ,  A23V2002/00

Abstract: Potato protein, in combination with other vegetable proteins, replaces a portion of the total protein in a nutrition drink or shake or other nutritional composition intended for oral consumption. By suitable selection of the types and amounts of these proteins the overall cost of manufacturing the nutritional composition can be reduced without adversely affecting its other desirable properties such as nutritional value, stability, solubility, clarity, taste, and mouthfeel.

公开(公告)号：US09693577B2

公开(公告)日：2017-07-04

申请号：US14043470

申请日：2013-10-01

Applicant: Abbott Laboratories

Inventor： Charles Helmke ,  Paul Johns ,  Ann Kensler

IPC: A23J1/00 ,  A23L1/30 ,  A23L3/46 ,  A23L33/00 ,  A23L33/10 ,  A23L33/165

CPC classification number: A23L33/10 ,  A23L3/46 ,  A23L33/165 ,  A23L33/40 ,  A23V2002/00

Abstract: Spray dried nutritional powders include soluble calcium, protein, and at least one of a soluble citrate, a soluble phosphate, and combinations thereof as at least one chelating agent. At least a portion of the soluble calcium is calcium HMB. At least a portion of the protein is soluble protein. The spray dried nutritional powders have a weight ratio of soluble calcium binding capacity to total soluble calcium of from about 2.3:1 to about 12:1. The calcium HMB, the at least one chelating agent, and the protein are spray dried together.

公开(公告)号：US20170178321A1

公开(公告)日：2017-06-22

申请号：US15379250

申请日：2016-12-14

Applicant: Abbott Laboratories

Inventor： Rene Nieves Alicea ,  Wenjing Li

IPC: G06T7/00 ,  G06K9/52 ,  G06K9/62 ,  G06K9/46

CPC classification number: G06T7/0012 ,  G06K9/00127 ,  G06K9/0014 ,  G06K9/00147 ,  G06K9/4604 ,  G06K9/4652 ,  G06K9/4661 ,  G06K9/525 ,  G06K9/6267 ,  G06K2009/4666 ,  G06K2209/05 ,  G06T2207/10056 ,  G06T2207/30024

Abstract: The instant disclosure provides methods of extracting stain-independent features from digital images of histologically stained cells. Stain-independent features provide consistent assessment of cell morphology in the presence of staining variation and across different stains or stain formulations. Improved consistency in cell morphology assessments finds use in automated cell classification and other image processing applications. Also included are systems for practicing the described methods. The instant disclosure also provides computer readable media storing instructions that, when executed by a computing device, cause the computing device and/or components of a described system to perform steps of a method involving of extraction of stain-independent features from digital images.

公开(公告)号：US20170165297A1

公开(公告)日：2017-06-15

申请号：US15441658

申请日：2017-02-24

Applicant: ABBOTT LABORATORIES

Inventor： Suzette Pereira ,  Sean Garvey ,  Neile Edens

IPC: A61K33/30 ,  A61K31/353 ,  A61K36/82 ,  A61K36/48 ,  A61K38/01 ,  A23L33/00 ,  A23L2/66 ,  A23L33/105 ,  A23L33/16 ,  A23L33/175 ,  A23L33/19 ,  A61K9/00 ,  A61K38/39

CPC classification number: A61K33/30 ,  A23L2/66 ,  A23L33/105 ,  A23L33/16 ,  A23L33/17 ,  A23L33/175 ,  A23L33/19 ,  A23L33/195 ,  A23L33/40 ,  A23V2002/00 ,  A61K9/0095 ,  A61K31/353 ,  A61K35/20 ,  A61K36/48 ,  A61K36/82 ,  A61K38/011 ,  A61K38/018 ,  A61K38/39 ,  A61K2300/00

Abstract: Disclosed herein are methods for enhancing the efficacy of epigallocatechin gallate (“EGCg”) in mitigating skeletal muscle loss in a subject. Providing EGCg to a subject in a nutritional composition reduces muscle protein degradation, thereby mitigating skeletal muscle loss in the subject. The combination of EGCg with zinc in a nutritional composition enhances the mitigating effect that EGCg has on muscle loss. Specifically, when used in combination, a nutritional composition containing both EGCg and zinc requires less EGCg to obtain the same mitigating effect that occurs in the same nutritional composition containing EGCg but no zinc.

公开(公告)号：USD782696S1

公开(公告)日：2017-03-28

申请号：US29551949

申请日：2016-01-19

Applicant: ABBOTT LABORATORIES

Designer： James P. Perry ,  Jeremy McBroom ,  Bryan Eliot Rolfs

公开(公告)号：US09592045B2

公开(公告)日：2017-03-14

申请号：US14269792

申请日：2014-05-05

Applicant: Abbott Laboratories

Inventor： Laveille Kao Voss ,  Erik Kristian Walberg

IPC: A61B17/08 ,  A61B17/04 ,  A61B17/00 ,  A61B17/34 ,  A61M25/01

CPC classification number: A61B17/0469 ,  A61B17/0057 ,  A61B17/0482 ,  A61B17/062 ,  A61B17/10 ,  A61B17/3403 ,  A61B17/3421 ,  A61B2017/00296 ,  A61B2017/00469 ,  A61B2017/00473 ,  A61B2017/00477 ,  A61B2017/00641 ,  A61B2017/00663 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/3405 ,  A61B2017/3419 ,  A61B2017/3445 ,  A61B2017/3449 ,  A61M25/0111 ,  A61M25/09041 ,  A61M39/06

Abstract: In accordance with the present invention there is provided apparatuses and methods for using a medical instrument including a sizing and positioning adapter. The apparatus comprises an adapter for a medical instrument, the adapt having a body having a shim portion and an instrument holding portion adjacent the shim portion, wherein the shim portion provides an enlarged peripheral surface adjacent the medical instrument such that when the medical instrument is held in the instrument holding portion and the medical instrument and body are inserted through an opening in a patient tissue, at least a portion of the enlarged peripheral surface is in contact with at least a portion of the periphery of the opening in the patient tissue.

Abstract translation: 根据本发明，提供了一种用于使用包括尺寸和定位适配器的医疗器械的设备和方法。 所述装置包括用于医疗器械的适配器，所述适配器具有具有垫片部分的主体和邻近所述垫片部分的器械保持部分，其中所述垫片部分邻近所述医疗器械提供扩大的周边表面，使得当所述医疗器械被保持时 在仪器保持部分中，医疗器械和身体通过病人组织中的开口插入，所述扩大的周面的至少一部分与患者组织中的开口的周边的至少一部分接触。

公开(公告)号：US20170052184A1

公开(公告)日：2017-02-23

申请号：US15189646

申请日：2016-06-22

Applicant: ABBOTT LABORATORIES ,  ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

Inventor： ROBERT ZIEMANN ,  APRIL AHLBERG ,  DAVID HAWKSWORTH ,  BRYAN TIEMAN ,  A. SCOTT MUERHOFF ,  CHRISTOPHER MAROHNIC ,  KATHY OTIS ,  ANDREA BRANCH ,  FRANCIS ENG

IPC: G01N33/576 ,  C07K16/10

Abstract: The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.

Abstract translation: 本公开提供了使用HCV核心脂质结合结构域和DNA结合结构域单克隆抗体或抗体片段的检测方法。 在某些实施方案中，脂质结合结构域单克隆抗体或抗体片段识别HCV核心蛋白质的第141至161位氨基酸中的表位，DNA结合结构域抗体或抗体片段识别氨基酸95-123中的表位（例如氨基酸 99-117）HCV核心蛋白。

公开(公告)号：US20170023568A1

公开(公告)日：2017-01-26

申请号：US15287605

申请日：2016-10-06

Applicant: Abbott Laboratories

Inventor： Susan E. Brophy ,  David J. Hawksworth ,  Dinesh O. Shah ,  Robert W. Siegel ,  Bryan C. Tieman ,  Bailin Tu ,  Joan D. Tyner ,  Robert N. Ziemann

IPC: G01N33/569 ,  C07K16/20

CPC classification number: G01N33/56905 ,  C07K16/20 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/92 ,  G01N2333/44 ,  G01N2469/10 ,  G01N2469/20 ,  G01N2496/00

Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.

Abstract translation: 本公开涉及使用试剂检测克氏锥虫的表位的试剂和方法。

公开(公告)号：US20160377620A1

公开(公告)日：2016-12-29

申请号：US15258979

申请日：2016-09-07

Applicant: ABBOTT LABORATORIES

Inventor： Brian C. Rodgers ,  Graham J. Burch

IPC: G01N33/576

CPC classification number: G01N33/5767 ,  C07K16/109 ,  G01N33/56966 ,  G01N33/56983 ,  G01N33/686 ,  G01N2333/186 ,  G01N2469/10 ,  G01N2469/20

Abstract: An in vitro method that allows detection of hepatitis C by detecting hepatitis C virus (HCV) core protein and antibodies to HCV core protein (anti-core antibodies) in a single assay is provided. Cross-reactivity is eliminated in the method preferably by utilizing short peptides, each of which has an amino acid sequence that corresponds to an immunodominant region of the native core protein but which does not wholly encompass the epitope bound by the antibodies utilized in the method. The method can be used to detect the presence of HCV in a subject, and/or to determine the suitability of donor blood or blood products for transfusion purposes. Also provided are diagnostic kits for carrying out the method and a process for selecting suitable capture peptides and monoclonal antibodies for use in the combination method.

公开(公告)号：US20160367241A1

公开(公告)日：2016-12-22

申请号：US15192481

申请日：2016-06-24

Applicant: Abbott Laboratories

Inventor： Joshua Stafford

IPC: A61B17/04 ,  A61B17/00

CPC classification number: A61B17/0469 ,  A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00663 ,  A61B2017/00672 ,  A61B2017/0477

Abstract: A device for suturing an opening in a tissue, having an elongated shaft, at least two arms movable to a deployed positioning which the arms are non-perpendicular to the shaft, the arms having needle receiving portions; and needles advanceable longitudinally along the shaft toward the needle receiving portions, the needles exiting through side walls of the shaft at a location proximal to the arms.

Abstract translation: 一种用于缝合组织中具有细长轴的开口的装置，至少两个臂可移动到展开位置，所述展开定位臂与所述轴不垂直，所述臂具有针接收部分; 并且针可沿着轴朝向针接收部分纵向前进，所述针从靠近臂的位置离开轴的侧壁。