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公开(公告)号：US11226280B2
公开(公告)日：2022-01-18
申请号：US16421201
申请日：2019-05-23
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Kam Lin Wong , Damian John Verdnik , Leigh Whiting , Mahmoud Janbakhsh
Abstract: The present disclosure provides methods for automated slide assessments made in conjunction with digital image-based microscopy. Automated methods of acquiring patient information and specimen information from prepared slides, and digitally linking such information into patient-tagged specimen data, are provided. Also provided are methods that include automatically identifying an optimal area for morphological assessment of a blood smear on a hematological slide, including methods for triggering the analysis of such an area, e.g., using an automated digital image-based hematology system. The present disclosure also provides devices, systems and computer readable media for use in performing processes of the herein described methods.
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公开(公告)号：US10445876B2
公开(公告)日：2019-10-15
申请号：US15379250
申请日：2016-12-14
Applicant: Abbott Laboratories
Inventor： Rene Nieves Alicea , Wenjing Li
Abstract: The instant disclosure provides methods of extracting stain-independent features from digital images of histologically stained cells. Stain-independent features provide consistent assessment of cell morphology in the presence of staining variation and across different stains or stain formulations. Improved consistency in cell morphology assessments finds use in automated cell classification and other image processing applications. Also included are systems for practicing the described methods. The instant disclosure also provides computer readable media storing instructions that, when executed by a computing device, cause the computing device and/or components of a described system to perform steps of a method involving of extraction of stain-independent features from digital images.
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公开(公告)号：US20170178361A1
公开(公告)日：2017-06-22
申请号：US15378495
申请日：2016-12-14
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Marilou L. Coleman , Walter G. Stonas , Willie J. Cowart , Wenjing Li , Ema C. Ciucurel
CPC classification number: G06T7/0014 , G01N15/1475 , G01N33/52 , G06K9/00127 , G06K9/0014 , G06K9/00147 , G06K9/3241 , G06K9/4642 , G06K9/4652 , G06K9/6212 , G06T7/90 , G06T2207/10024 , G06T2207/30024
Abstract: The present disclosure includes methods of assessing a histologically stained specimen based on a determined color signature of a region of interest of the specimen. Such assessments may be performed for a variety of purposes including but not limited to assessing the quality of the histological stain, as part of identifying one or more biologically relevant features of the image, as part of differentiating one feature of the image from other features of the image, identifying an anomalous area of the stained specimen, classifying cells of the specimen, etc. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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4.发明申请公开(公告)号：US20170010193A1
公开(公告)日：2017-01-12
申请号：US15208458
申请日：2016-07-12
Applicant: Abbott Laboratories
Inventor： Abe S. Mamaghani , Koshy T. Chacko , Rupa Rao , Rene Nieves Alicea
IPC: G01N1/31
CPC classification number: G01N1/312 , G01N1/30 , G01N2001/302 , G01N2001/307 , Y10T436/2575
Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.
Abstract translation: 本公开提供了用于快速有效地进行罗曼诺斯基型污渍的方法，特别是Wright-Giemsa和May-Grünwald污渍。 该方法大大减少了完成Wright-Giemsa染色或生物样品中足够质量的May-Grünwald染色所需的总体时间。 主题方法可以应用于手动和自动染色程序。
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5.发明授权公开(公告)号：US09404837B2
公开(公告)日：2016-08-02
申请号：US14692508
申请日：2015-04-21
Applicant: Abbott Laboratories
Inventor： Abe S. Mamaghani , Koshy T. Chacko , Rupa Rao , Rene Nieves Alicea
CPC classification number: G01N1/312 , G01N1/30 , G01N2001/302 , G01N2001/307 , Y10T436/2575
Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.
Abstract translation: 本公开提供了用于快速有效地进行罗曼诺斯基型污渍的方法，特别是Wright-Giemsa和May-Grünwald污渍。 该方法大大减少了完成Wright-Giemsa染色或生物样品中足够质量的May-Grünwald染色所需的总体时间。 主题方法可以应用于手动和自动染色程序。
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Patent Agency Ranking
公开(公告)号：US20210131928A1
公开(公告)日：2021-05-06
申请号：US17096711
申请日：2020-11-12
Applicant: Abbott Laboratories
Inventor： Abe S. Mamaghani , Koshy T. Chacko , Rupa Rao , Rene Nieves Alicea
Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.
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公开(公告)号：US20190310170A1
公开(公告)日：2019-10-10
申请号：US16357617
申请日：2019-03-19
Applicant: Abbott Laboratories
Inventor： Abe S. Mamaghani , Koshy T. Chacko , Rupa Rao , Rene Nieves Alicea
Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.
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公开(公告)号：US10395368B2
公开(公告)日：2019-08-27
申请号：US15378495
申请日：2016-12-14
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Marilou L. Coleman , Walter G. Stonas , Willie J. Cowart , Wenjing Li , Ema C. Olah
Abstract: The present disclosure includes methods of assessing a histologically stained specimen based on a determined color signature of a region of interest of the specimen. Such assessments may be performed for a variety of purposes including but not limited to assessing the quality of the histological stain, as part of identifying one or more biologically relevant features of the image, as part of differentiating one feature of the image from other features of the image, identifying an anomalous area of the stained specimen, classifying cells of the specimen, etc. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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公开(公告)号：US20180156713A1
公开(公告)日：2018-06-07
申请号：US15832329
申请日：2017-12-05
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Kam Lin Wong , Damian John Verdnik , Leigh Whiting , Mahmoud Janbakhsh
CPC classification number: G01N15/1463 , G01N15/0227 , G01N15/1434 , G01N15/1475 , G01N2015/0073 , G01N2015/1006 , G01N2015/1452 , G01N2015/1465 , G01N2015/1486 , G01N2015/1493 , G01N2015/1497 , G06K9/4604 , G06T7/0016 , G06T7/11 , G06T2207/10056 , G06T2207/30024 , G06T2207/30242
Abstract: The present disclosure provides methods for automated slide assessments made in conjunction with digital image-based microscopy. Automated methods of acquiring patient information and specimen information from prepared slides, and digitally linking such information into patient-tagged specimen data, are provided. Also provided are methods that include automatically identifying an optimal area for morphological assessment of a blood smear on a hematological slide, including methods for triggering the analysis of such an area, e.g., using an automated digital image-based hematology system. The present disclosure also provides devices, systems and computer readable media for use in performing processes of the herein described methods.
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公开(公告)号：US09909963B2
公开(公告)日：2018-03-06
申请号：US15208458
申请日：2016-07-12
Applicant: Abbott Laboratories
Inventor： Abe S. Mamaghani , Koshy T. Chacko , Rupa Rao , Rene Nieves Alicea
CPC classification number: G01N1/312 , G01N1/30 , G01N2001/302 , G01N2001/307 , Y10T436/2575
Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.
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