公开(公告)号：US20200320693A1

公开(公告)日：2020-10-08

申请号：US16837733

申请日：2020-04-01

Applicant: OPTOS PLC

Inventor： GAVIN ROBERTSON ,  ALAN DUNCAN FLEMING

IPC: G06T7/00 ,  G06T7/11 ,  G06T7/155 ,  G06T5/40 ,  G16H50/30 ,  G16H30/40

Abstract: A computer-implemented method, system, and computer-readable medium, for determining a level of hypertension of a person. The method has steps of: acquiring image data defining a retinal image of a retina of the person that has been captured by a retinal imaging system; processing the image data to identify a plurality of vessel segments present in the retinal image; determining respective widths of vessel segments of at least a subset of the plurality of vessel segments present in the retinal image; and calculating, as a vascular summary metric, at least one average value or median value of the determined widths of the vessel segments present in the retinal image, to determine a level of hypertension by which the person has been affected.

公开(公告)号：US20200058122A1

公开(公告)日：2020-02-20

申请号：US16543063

申请日：2019-08-16

Applicant: Optos PLC

Inventor： Peter Robert Wakeford ,  David Clifton

IPC: G06T7/00 ,  G06T7/40

Abstract: A method, apparatus, and computer-readable medium, for assessing image quality of an image produced by a scanning imaging system. The method comprises acquiring (S10) image data of an image produced by the scanning imaging system and calculating (S20 to S40), for each section of the image: a respective first value measuring at least one of sharpness or contrast of at least a part of the section, the measuring depending on noise, a respective second value measuring noise in at least a part of the section, and a respective third value indicating image quality, by combining the first and second values. The combining is such that calculated third values have a weaker dependency on the noise than the first values. The method further comprises determining (S50) a quality score that is indicative of image quality of the image based on a variation of the calculated third values among the sections.

公开(公告)号：US10357150B2

公开(公告)日：2019-07-23

申请号：US15484935

申请日：2017-04-11

Applicant: OPTOS PLC

Inventor： Jano Van Hemert ,  Michael Verhoek

IPC: G06K9/00 ,  A61B3/00 ,  A61B3/14 ,  G06T7/64 ,  A61B3/10 ,  A61B3/12 ,  G06T7/00

Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).

公开(公告)号：US10178951B2

公开(公告)日：2019-01-15

申请号：US15013545

申请日：2016-02-02

Applicant: Optos PLC

Inventor： Hind Azegrouz

IPC: A61B3/12 ,  A61B3/10 ,  G02B26/12 ,  A61B3/00

Abstract: A laser scanning system adapted to produce a scanned image including a number of lines of an object. A method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.

公开(公告)号：US09924862B2

公开(公告)日：2018-03-27

申请号：US14422671

申请日：2013-10-01

Applicant: Optos PLC

Inventor： William Brown ,  Michael E. Sullivan ,  Anthony Corcoran ,  Derek Swan

IPC: A61B3/14 ,  A61B3/00 ,  A61B3/10 ,  A61B3/12

CPC classification number: A61B3/102 ,  A61B3/1015 ,  A61B3/1025 ,  A61B3/1225 ,  A61B3/14

Abstract: A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.

公开(公告)号：US20170367889A1

公开(公告)日：2017-12-28

申请号：US15543549

申请日：2016-01-26

Applicant: OPTOS PLC

Inventor： Derek Swan

IPC: A61F9/008 ,  A61B3/12

CPC classification number: A61F9/00821 ,  A61B3/12 ,  A61F2009/00863 ,  A61F2009/00878 ,  A61F2009/00897

Abstract: A method of determining control parameters of a retinal treatment system comprising acquiring an image of a retina of a subject's eye using an imaging laser and an optical system of the retinal treatment system, presenting an image of the retina to a user of the retinal treatment system, receiving from the user location data of the retinal image that locates at least one treatment site of the retina, receiving from the user a required laser light pattern for use on the treatment site, using the location data to determine a location control parameter which causes the optical system to direct laser light from a treatment laser of the retinal treatment system to the treatment site, and using the required laser light pattern to determine a pattern control parameter which causes the treatment laser to produce a laser light pattern which passes through the optical system and results in the required laser light pattern at the treatment site.

公开(公告)号：US20170309015A1

公开(公告)日：2017-10-26

申请号：US15139182

申请日：2016-04-26

Applicant: Optos PLC

Inventor： Alan Duncan Fleming

IPC: G06T7/00 ,  A61B3/00 ,  G06K9/44 ,  A61B3/14 ,  G06K9/42

CPC classification number: A61B3/0025 ,  A61B3/14 ,  G06K9/42 ,  G06K9/44 ,  G06T7/0012 ,  G06T7/004 ,  G06T7/70 ,  G06T7/73 ,  G06T2207/10024 ,  G06T2207/10064 ,  G06T2207/20061 ,  G06T2207/30041 ,  G06T2207/30101

Abstract: The disclosure relates to a non-transitory computer-readable storage medium storing computer program instructions which, when executed by a processor, cause the processor to process image data defining an image of a retina to determine a location of an anatomical feature of the retina in the image by receiving the image data; calculating, for each of a plurality of pixels of the image data, a respective local orientation vector indicative of the orientation of any blood vessel present in the image; calculating a normalised local orientation vector for each of the plurality of pixels; operating on an array of accumulators, wherein each accumulator in the array is associated with a respective pixel of the image data; and determining the location of the anatomical feature in the image of the retina using the location of a pixel of the image data which is associated with an accumulator having accumulated an accumulated value.

公开(公告)号：US20170215722A1

公开(公告)日：2017-08-03

申请号：US15484935

申请日：2017-04-11

Applicant: OPTOS PLC

Inventor： Jano Van Hemert ,  Michael Verhoek

IPC: A61B3/00 ,  G06T7/64 ,  A61B3/10 ,  G06T7/00 ,  A61B3/14 ,  A61B3/12

CPC classification number: A61B3/0025 ,  A61B3/1005 ,  A61B3/1025 ,  A61B3/12 ,  A61B3/14 ,  G06T7/0012 ,  G06T7/64 ,  G06T2207/30041

Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).

公开(公告)号：US20160157714A1

公开(公告)日：2016-06-09

申请号：US15013504

申请日：2016-02-02

Applicant: Optos PLC

Inventor： Hind Azegrouz

IPC: A61B3/10 ,  A61B3/00

CPC classification number: A61B3/1025 ,  A61B3/0025 ,  A61B3/12 ,  G02B26/127

Abstract: A method of reducing jitter error in a laser scanning system adapted to produce a scanned image including a number of lines of an object. The method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.

Abstract translation: 一种减少激光扫描系统中的抖动误差的方法，适用于产生包括物体的多条线的扫描图像。 该方法包括以下步骤：提供参考对象，其被布置为使得由激光扫描系统产生的扫描图像包括参考对象的参考图像，处理参考图像以计算由不可重复位移的 参考图像，并且响应于所计算的误差来调整激光扫描系统的至少一个操作参数。

公开(公告)号：US20150324966A1

公开(公告)日：2015-11-12

申请号：US14654249

申请日：2014-02-19

Applicant: OPTOS PLC

Inventor： David CLIFTON ,  Ralph Allen PINNOCK

IPC: G06T7/00 ,  G06T5/20

CPC classification number: G06T7/003 ,  A61B3/0025 ,  A61B3/1225 ,  G06T5/20 ,  G06T7/136 ,  G06T7/32 ,  G06T7/337 ,  G06T2207/20164 ,  G06T2207/30041 ,  G06T2207/30101

Abstract: An image processing apparatus uses first and second digital vascular image data to register two images. The two images may be from different imaging modes. The first and second images are processed with a two-dimensional, directional filter (500) that has the effect of producing clusters of orthogonally adjacent image data points in which the magnitude of an intensity gradient between each orthogonally adjacent image data point is less than a predetermined value. Subsequently, common clusters are identified between the first and second image data using a corner detecting algorithm (600). The directional filter produces “stepping” features, where vascular features would otherwise appear with smooth edges. These numerous features are identified by the corner detecting algorithm and can be used (1000) for registering common clusters between the first and second image data. The filter may be a rotating Gabor filter matched to vascular features in the images.

Abstract translation: 图像处理装置使用第一和第二数字血管图像数据来登记两个图像。 两个图像可以来自不同的成像模式。 第一和第二图像用二维方向滤波器（500）处理，其具有产生正交相邻图像数据点的聚类的效果，其中每个正交相邻图像数据点之间的强度梯度的幅度小于 预定值。 随后，使用角部检测算法（600）在第一和第二图像数据之间识别公共集群。 方向滤波器产生“步进”特征，其中血管特征将以平滑的边缘出现。 这些许多特征由角部检测算法识别，并且可以使用（1000）来注册第一和第二图像数据之间的公共簇。 滤波器可以是与图像中的血管特征匹配的旋转Gabor滤波器。