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公开(公告)号:US20210022601A1
公开(公告)日:2021-01-28
申请号:US16930465
申请日:2020-07-16
Applicant: Optos Plc
Inventor: Jano van Hemert , Michael Verhoek
Abstract: A method of processing functional OCT image data, acquired by an OCT scanner scanning a retina that is being repeatedly stimulated by a light stimulus, to obtain a response of the retina to the light stimulus, comprising: receiving OCT image data generated by the OCT scanner repeatedly scanning the retina over a time period, and a sequence of stimulus indicators each indicative of a stimulation of the retina by the light stimulus in a respective time interval of a sequence of time intervals spanning the time period; calculating, for each stimulus indicator, a product of the stimulus indicator and a respective windowed portion of the sequence of B-scans comprising a B-scan based on a portion of the OCT image data generated while the retina was being stimulated in accordance with the stimulus indicator; and combining the calculated products to generate the indication of the response.
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公开(公告)号:US11857257B2
公开(公告)日:2024-01-02
申请号:US18071677
申请日:2022-11-30
Applicant: OPTOS PLC
Inventor: Jano van Hemert , Michael Verhoek
CPC classification number: A61B3/102 , A61B3/0008 , A61B3/0025 , G06T7/0012 , G06T7/11 , G06T2207/30041
Abstract: A method of processing functional OCT image data, acquired by an OCT scanner scanning a retina that is being repeatedly stimulated by a light stimulus, to obtain a response of the retina to the light stimulus, comprising: receiving OCT image data generated by the OCT scanner repeatedly scanning the retina over a time period, and a sequence of stimulus indicators each indicative of a stimulation of the retina by the light stimulus in a respective time interval of a sequence of time intervals spanning the time period; calculating, for each stimulus indicator, a product of the stimulus indicator and a respective windowed portion of the sequence of B-scans comprising a B-scan based on a portion of the OCT image data generated while the retina was being stimulated in accordance with the stimulus indicator; and combining the calculated products to generate the indication of the response.
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公开(公告)号:US20140327877A1
公开(公告)日:2014-11-06
申请号:US14267642
申请日:2014-05-01
Applicant: Optos PLC
Inventor: Jano Van Hemert , Michael Verhoek
IPC: A61B3/14
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/1025 , A61B3/12 , A61B3/14 , G06T7/0012 , G06T7/64 , G06T2207/30041
Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).
Abstract translation: 一种确定眼睛视网膜的几何测量的方法,包括获得眼睛(34)的视网膜的至少一部分的二维表示,导出几何重新映射,其将视网膜部分的二维表示转换为 使用视网膜部分的二维表示的一个或多个坐标来定义视网膜部分(36)的三维表示,以使用几何重新映射来限定在二维表示(38)上对视网膜进行的几何测量 将视网膜部分的二维表示的或每个坐标转换为视网膜部分(40)的三维表示的等效坐标,并且使用视网膜部分的三维表示的或每个等效坐标来确定 眼睛视网膜的几何测量(42)。
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公开(公告)号:US12048481B2
公开(公告)日:2024-07-30
申请号:US17207077
申请日:2021-03-19
Applicant: OPTOS PLC
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/102 , G16H30/40
Abstract: A technique for generating a mapping relating values of a scan parameter of an ocular imaging apparatus that are indicative of scan locations in an eye at which the apparatus acquires digital images of imaged regions of the eye, to respective values of a conversion factor for calculating a distance between designated ocular features in the imaged regions, by: simulating light ray propagation to relate each value of the scan parameter in a sequence of scan parameter values to a corresponding location in a model eye; calculating, for each scan parameter value, a distance between the corresponding location in the model eye and a location in the model eye corresponding to an adjacent value in the sequence; and using the calculated distances to generate a respective value of the conversion factor for each scan parameter value.
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公开(公告)号:US20210298592A1
公开(公告)日:2021-09-30
申请号:US17207077
申请日:2021-03-19
Applicant: OPTOS PLC
Abstract: A technique for generating a mapping relating values of a scan parameter of an ocular imaging apparatus that are indicative of scan locations in an eye at which the apparatus acquires digital images of imaged regions of the eye, to respective values of a conversion factor for calculating a distance between designated ocular features in the imaged regions, by: simulating light ray propagation to relate each value of the scan parameter in a sequence of scan parameter values to a corresponding location in a model eye; calculating, for each scan parameter value, a distance between the corresponding location in the model eye and a location in the model eye corresponding to an adjacent value in the sequence; and using the calculated distances to generate a respective value of the conversion factor for each scan parameter value.
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公开(公告)号:US20190290119A1
公开(公告)日:2019-09-26
申请号:US16438298
申请日:2019-06-11
Applicant: OPTOS PLC
Inventor: Jano Van Hemert , Michael Verhoek
Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).
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公开(公告)号:US10349825B2
公开(公告)日:2019-07-16
申请号:US15308028
申请日:2015-05-01
Applicant: Optos PLC
Inventor: Jano van Hemert , Michael Verhoek , David Brown , Charles Wykoff , Daniel Croft
Abstract: A method of determining a measurement of at least one cell type in an eye, comprising (i) obtaining a map of the cell type in the eye, (ii) obtaining a representation of the retina of the eye, (iii) matching the eye cell type map to the representation of the retina of the eye, (iv) defining a region of interest on the representation of the retina of the eye, (v) calculating a size of the region of interest on the representation of the retina of the eye, (vi) using the matched eye cell type map and the size of the region of interest to determine a measure of the cell type in the region of interest of the retina of the eye.
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公开(公告)号:US09649031B2
公开(公告)日:2017-05-16
申请号:US14267642
申请日:2014-05-01
Applicant: Optos PLC
Inventor: Jano Van Hemert , Michael Verhoek
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/1025 , A61B3/12 , A61B3/14 , G06T7/0012 , G06T7/64 , G06T2207/30041
Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).
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公开(公告)号:US11540712B2
公开(公告)日:2023-01-03
申请号:US16930465
申请日:2020-07-16
Applicant: Optos Plc
Inventor: Jano van Hemert , Michael Verhoek
Abstract: A method of processing functional OCT image data, acquired by an OCT scanner scanning a retina that is being repeatedly stimulated by a light stimulus, to obtain a response of the retina to the light stimulus, comprising: receiving OCT image data generated by the OCT scanner repeatedly scanning the retina over a time period, and a sequence of stimulus indicators each indicative of a stimulation of the retina by the light stimulus in a respective time interval of a sequence of time intervals spanning the time period; calculating, for each stimulus indicator, a product of the stimulus indicator and a respective windowed portion of the sequence of B-scans comprising a B-scan based on a portion of the OCT image data generated while the retina was being stimulated in accordance with the stimulus indicator; and combining the calculated products to generate the indication of the response.
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公开(公告)号:US11259696B2
公开(公告)日:2022-03-01
申请号:US16438298
申请日:2019-06-11
Applicant: OPTOS PLC
Inventor: Jano Van Hemert , Michael Verhoek
Abstract: A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).
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