公开(公告)号：US08076142B2

公开(公告)日：2011-12-13

申请号：US12001234

申请日：2007-12-11

Applicant: Xiang Huang ,  Ming Cheng ,  Haiping Hong ,  Yan Liu ,  Kangfeng Mei

Inventor： Xiang Huang ,  Ming Cheng ,  Haiping Hong ,  Yan Liu ,  Kangfeng Mei

IPC: C12N15/82 ,  C12N5/04 ,  A01H5/00

CPC classification number: C12N15/8205 ,  A01H3/00 ,  A01H4/005

Abstract: Disclosed herein are rooted plant assay systems, methods of making rooted plant assay systems, and methods of using rooted plant assay systems for high throughput screening of test polynucleotides for their ability to effect phenotypic traits having agricultural value.

Abstract translation: 本文公开了根植物测定系统，制造根植物测定系统的方法，以及使用根植物测定系统对测试多核苷酸进行高通量筛选以影响具有农业价值的表型性状的能力的方法。

公开(公告)号：US20110190602A1

公开(公告)日：2011-08-04

申请号：US13075664

申请日：2011-03-30

Applicant: Weihu Wang ,  Feng Xu ,  Yufei Xie ,  Yan Liu

Inventor： Weihu Wang ,  Feng Xu ,  Yufei Xie ,  Yan Liu

IPC: A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  A61B2560/0252

Abstract: The present invention provides a method for measuring blood oxygen at a finger, comprising the following steps: 10) measuring blood oxygen content and finger temperature of the human body; 20) giving corresponding prompts according to the blood oxygen content and the finger temperature measured in the step 10). The present invention further provides a finger-clipped oximeter, comprising a control unit, a blood oxygen measurement unit, a finger temperature measurement unit, an output unit and a power management unit. The method for measuring blood oxygen at a finger and the finger-clipped oximeter provided by the present invention can measure the finger temperature of the human body, consider the measured finger temperature as a reference of the measured blood oxygen content of the human body and present it to the user together with the measured blood oxygen content, so as to assist the user in making a more accurate estimation on the blood oxygen content and the health condition of the person under test.

Abstract translation: 本发明提供了一种测量手指血氧的方法，包括以下步骤：10）测量人体的血氧含量和手指温度; 20）根据步骤10）中测量的血氧含量和手指温度给出相应的提示。 本发明还提供一种手指夹式血氧计，包括控制单元，血氧测量单元，手指温度测量单元，输出单元和电源管理单元。 本发明提供的用于测量手指血氧的手指和手指夹式血氧计的方法可以测量人体的手指温度，将所测量的手指温度视为人体所测血氧含量的参考， 它与测量的血氧含量一起向用户提供，以帮助用户对被测试者的血氧含量和健康状况进行更准确的估计。

公开(公告)号：US07885794B2

公开(公告)日：2011-02-08

申请号：US11947859

申请日：2007-11-30

Applicant: Yan Liu ,  Florent Perronnin

Inventor： Yan Liu ,  Florent Perronnin

IPC: G06F17/50 ,  G06K9/62 ,  G06F17/30

CPC classification number: G06F17/30247 ,  G06K9/6226

Abstract: Object comparison is disclosed, including: adapting N universal mixture model components to a first object to generate N corresponding first object mixture model components, where N is an integer greater than or equal to two; and generating a similarity measure based on component-by-component comparison of the N first object mixture model components with corresponding N second object mixture model components obtained by adaptation of the N universal mixture model components to a second object.

Abstract translation: 公开了对象比较，包括：将N个通用混合模型组件适配到第一对象以生成N个相应的第一对象混合模型分量，其中N是大于或等于2的整数; 以及基于所述N个第一对象混合模型分量与通过将所述N个通用混合模型分量适应于第二对象而获得的相应的N个第二对象混合模型分量，进行相似度测量。

公开(公告)号：US20100307919A1

公开(公告)日：2010-12-09

申请号：US12816319

申请日：2010-06-15

Applicant: Yan Liu ,  Nebojsa Avdalovic

Inventor： Yan Liu ,  Nebojsa Avdalovic

IPC: B01D61/48 ,  B01D61/44

CPC classification number: B01D69/02 ,  B01D15/16 ,  B01D15/166 ,  B01D61/44 ,  B01D61/48 ,  B01D69/141 ,  G01N30/34 ,  G01N30/96 ,  G01N2030/965 ,  Y10T436/25

Abstract: An acid or base is generated in an aqueous solution by the steps of: (a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a first barrier (e.g., anion exchange membrane) substantially preventing liquid flow and transporting ions only of the same charge as said first ions, (b) providing a source of second ions of opposite charge adjacent an aqueous liquid in a second acid or base generation zone, separated by a second barrier transporting ions only of the same charge as the second ions, and (c) transporting ions across the first barrier by applying an electrical potential through said first and second zones to generate an acid-containing aqueous solution in one of said first or second zones and a base-containing aqueous solution in the other one which may be combined to form a salt. Also, electrolytic apparatus for performing the above method.

Abstract translation: 通过以下步骤在水溶液中产生酸或碱：（a）在第一酸或碱产生区中提供邻近水性液体的第一离子源，由第一势垒（例如阴离子交换膜）分开，基本上 防止液体流动并仅传输与所述第一离子相同电荷的离子，（b）在第二酸或碱产生区域中提供邻近含水液体的相反电荷的第二离子源，由第二阻挡层输送离子 与第二离子相同的电荷，以及（c）通过施加电势通过所述第一和第二区输送离子穿过第一屏障，以在所述第一或第二区之一中产生含酸的水溶液，并且含有碱 另一个可以组合形成盐的水溶液。 而且，用于执行上述方法的电解装置。

公开(公告)号：US20100285948A1

公开(公告)日：2010-11-11

申请号：US12808781

申请日：2008-01-16

Applicant: Yan Liu ,  Toru Nishimura

Inventor： Yan Liu ,  Toru Nishimura

IPC: B01J38/04 ,  B01J29/40 ,  B01J29/48 ,  B01J29/46 ,  C07C2/00

CPC classification number: B01J29/076 ,  B01J29/48 ,  B01J29/7876 ,  B01J29/90 ,  B01J38/04 ,  B01J2229/186 ,  B01J2229/34 ,  B01J2229/40 ,  C07C2/76 ,  C07C2529/48 ,  C10G45/68 ,  Y02P20/584 ,  C07C15/02

Abstract: A process for the pre-treatment of Mo/ZSM-5 and Mo/MCM-22 catalysts is provided, which process comprises heating the catalyst at 500° C. in the presence of propane. The treated catalyst, when used in the non-oxidative dehydrogenation of methane demonstrates improved benzene yield and catalyst stability as compared to catalysts pre-treated with He, methane or H2.

Abstract translation: 提供了用于预处理Mo / ZSM-5和Mo / MCM-22催化剂的方法，该方法包括在丙烷存在下在500℃下加热催化剂。 当用于甲烷的非氧化脱氢反应时，处理的催化剂与用He，甲烷或H 2预处理的催化剂相比，显示出苯产率和催化剂稳定性的改善。

公开(公告)号：US07790155B2

公开(公告)日：2010-09-07

申请号：US11177790

申请日：2005-07-08

Applicant: Sylvia Christakos ,  Yan Liu ,  Teresita Bellido

Inventor： Sylvia Christakos ,  Yan Liu ,  Teresita Bellido

IPC: A61K48/00 ,  C12N15/867 ,  C12N15/861 ,  C12N15/86

CPC classification number: C07K14/4747 ,  A61K48/00

Abstract: The present invention provides novel compositions containing a calbindin-D28k therapeutic element, which is involved in the regulation of apoptosis, and may be administered for the prevention of an abnormal apoptosis response in cells. In particular the compositions and methods of the present invention may be used for the prevention or induction of apoptosis in such cells types as osteoblasts and osteocytes. Specifically, the compositions and methods of the present invention are useful for the prevention of diseases associated with glucocorticoid induced cell death. Specifically, the compositions and methods of the present invention may be useful in the prevention of glucocorticoid induced cell death in osteoblasts and the treatment of such conditions as glucocorticoid induced osteoporosis.

Abstract translation: 本发明提供含有钙结合素-D28k治疗元件的新型组合物，其涉及凋亡调节，并且可以用于预防细胞中异常凋亡应答。 特别地，本发明的组合物和方法可用于预防或诱导类似于成骨细胞和骨细胞的类型的细胞凋亡。 具体地，本发明的组合物和方法可用于预防与糖皮质激素诱导的细胞死亡有关的疾病。 具体地说，本发明的组合物和方法可用于预防成骨细胞中糖皮质激素诱导的细胞死亡和治疗糖皮质激素诱导的骨质疏松症等病症。

公开(公告)号：US20100038245A1

公开(公告)日：2010-02-18

申请号：US12192781

申请日：2008-08-15

Applicant: Hamish Small ,  Yan Liu ,  Christopher A. Pohl

Inventor： Hamish Small ,  Yan Liu ,  Christopher A. Pohl

IPC: B01D59/42

CPC classification number: G01N30/96 ,  B01D61/427 ,  F04B17/00 ,  G01N30/32 ,  G01N30/34 ,  G01N30/6095

Abstract: A continuous electrochemical pump comprising a water generator compartment, an anode compartment on one side of said generator compartment, a cation exchange barrier, separating the generator compartment from the anode compartment, a first electrode in electrical communication with the anode compartment, a cathode compartment adjacent the generator chamber, an anion exchange barrier, separating the generation compartment from the cathode compartment, and a second electrode in electrical communication with the cathode compartment. Use of the pump as a sample concentrator. A feedback loop for the pump. A reservoir, with or without an intermediate piston, on the output side of the pump.

Abstract translation: 一种连续电化学泵，包括水发生器室，在所述发生器室的一侧上的阳极室，阳离子交换屏障，将发生器室与阳极室分开，与阳极室电连通的第一电极，邻近的阴极室 所述发生器室，阴离子交换屏障，将所述发电室与所述阴极室分开，以及与所述阴极室电连通的第二电极。 使用泵作为样品浓缩器。 泵的反馈回路。 在泵的输出侧具有或不具有中间活塞的储存器。

公开(公告)号：US20100009868A1

公开(公告)日：2010-01-14

申请号：US12374259

申请日：2007-09-11

Applicant: Hao Yan ,  Chenxiang Lin ,  Evaldas Katilius ,  Yan Liu

Inventor： Hao Yan ,  Chenxiang Lin ,  Evaldas Katilius ,  Yan Liu

IPC: C40B30/10 ,  C40B40/08 ,  C40B50/18

CPC classification number: C12N15/10 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00599 ,  B01J2219/00605 ,  B01J2219/00626 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00709 ,  B01J2219/00722 ,  B82Y30/00 ,  C40B50/14 ,  C40B50/16

Abstract: The present invention provides combinatorial encoding nucleic acid tiling arrays and methods for their use and synthesis.

Abstract translation: 本发明提供组合编码核酸贴片阵列及其使用和合成方法。

公开(公告)号：US20090325868A1

公开(公告)日：2009-12-31

申请号：US12119158

申请日：2008-05-12

Applicant: Yang Liu ,  Pan Zheng ,  Xing Chang ,  Lizhong Wang ,  Runhua Liu ,  Yin Wang ,  Yan Liu ,  Tao Zuo

Inventor： Yang Liu ,  Pan Zheng ,  Xing Chang ,  Lizhong Wang ,  Runhua Liu ,  Yin Wang ,  Yan Liu ,  Tao Zuo

IPC: A61K38/16 ,  A61K31/7052 ,  A61K31/4375 ,  A61K31/40 ,  A61K31/7064 ,  C12N5/00 ,  C12Q1/02 ,  C12Q1/68 ,  A61P35/00

CPC classification number: G01N33/57415 ,  A61K31/7088 ,  A61K38/1709 ,  A61K45/06 ,  G01N33/57434 ,  A61K2300/00

Abstract: Provided herein are methods of treating a cancer in a subject comprising administering a FOXP3 protein, a nucleic acid encoding a FOXP3 protein, or an inducing compound which induces FOXP3 protein expression. Methods of altering a phenotype of a cancer cell or tumor cell, methods of inhibiting growth of such cells, and methods of inducing apoptosis of these cells are also provided herein. These methods comprise contacting the cell with a FOXP3 protein, a nucleic acid encoding a FOXP3 protein, or an inducing compound which induces FOXP3 protein expression. Further provided herein are diagnostic methods, comprising comparing the expression or structure of a FOXP3 protein or FOXP3 gene in a test sample to that of a normal or prior sample. A method of screening a test compound for anti-cancer activity comprising administering to cells the test compound and measuring FOXP3 protein or FOXP3 gene expression is moreover provided herein.

Abstract translation: 本文提供了治疗受试者中的癌症的方法，包括施用FOXP3蛋白，编码FOXP3蛋白的核酸或诱导FOXP3蛋白表达的诱导化合物。 本文还提供了改变癌细胞或肿瘤细胞表型的方法，抑制细胞生长的方法和诱导细胞凋亡的方法。 这些方法包括使细胞与FOXP3蛋白，编码FOXP3蛋白的核酸或诱导FOXP3蛋白表达的诱导化合物接触。 本文进一步提供了诊断方法，其包括将测试样品中FOXP3蛋白或FOXP3基因的表达或结构与正常或先前样品的表达或结构进行比较。 筛选测试化合物用于抗癌活性的方法，其中还提供了向细胞施用测试化合物并测量FOXP3蛋白或FOXP3基因表达。

公开(公告)号：US07618826B2

公开(公告)日：2009-11-17

申请号：US11524513

申请日：2006-09-19

Applicant: Yan Liu ,  Victor Barreto ,  Christopher A. Pohl

Inventor： Yan Liu ,  Victor Barreto ,  Christopher A. Pohl

IPC: G01N30/02 ,  G01N33/00

CPC classification number: G01N30/96 ,  G01N2030/965

Abstract: An apparatus for ion chromatography comprising a suppressor comprising a housing and a liquid conduit segment disposed in the housing, the liquid conduit segment including a membrane, the membrane having an inlet section adjacent the inlet of the conduit segment and an outlet section adjacent the outlet of the conduit segment, the inlet section having ion exchange sites capable of transmitting ions of one charge, positive or negative, and the outlet section being substantially non-retentive electrostatically for charged ionic species. Also, the method of using the apparatus.

Abstract translation: 一种用于离子色谱的装置，其包括抑制器，该抑制器包括壳体和设置在壳体中的液体导管段，液体导管段包括膜，该膜具有邻近导管段入口的入口部分和邻近出口部分的出口部分 导管部分，入口部分具有能够传输一个电荷的离子的正离子或负离子的离子交换位置，并且对于带电离子物质，出口部分静电地基本上是非保持性的。 另外，使用该装置的方法。