公开(公告)号：US12102448B2

公开(公告)日：2024-10-01

申请号：US17697133

申请日：2022-03-17

Applicant: Cardiac Pacemakers, Inc.

Inventor： Qi An ,  Jeffrey E. Stahmann ,  Pramodsingh Hirasingh Thakur ,  Viktoria A Averina ,  Keith R. Maile

IPC: A61B5/00 ,  A61B5/02 ,  A61B5/0205 ,  A61B5/20 ,  G16H20/10 ,  G16H20/30 ,  G16H40/63 ,  G16H50/30 ,  G16H50/70 ,  A61B5/08

CPC classification number: A61B5/686 ,  A61B5/0031 ,  A61B5/02028 ,  A61B5/0205 ,  A61B5/201 ,  A61B5/4836 ,  A61B5/7225 ,  A61B5/725 ,  A61B5/7275 ,  G16H20/10 ,  G16H20/30 ,  G16H40/63 ,  G16H50/30 ,  G16H50/70 ,  A61B5/08

Abstract: Systems and methods for monitoring patients with a chronic disease such as heart failure are disclosed. The system may include a physiological sensor circuit to sense physiological signals and generate signal metrics from the physiological signals. The system may include a health status analyzer circuit to use the signal metrics to generate one or more stability indicators of patient health status, such as stability of heart failure status. The system may additionally generate one or more health status indicators indicating patient health status such as heart failure progression. A patient disposition decision may be generated using the health status indicators and the stability indicators to provide an indication of readiness for patient discharge from or a risk of admission to a hospital.

公开(公告)号：US12102435B2

公开(公告)日：2024-10-01

申请号：US17179640

申请日：2021-02-19

Applicant: OptoVibronex, LLC

Inventor： Frederick Howard Silver ,  Istvan Horvath ,  Nikita Uday Kelkar ,  Tanmay Manoj Deshmukh ,  Ruchit Girishchandra Shah

IPC: A61B5/22 ,  A61B5/00 ,  A61B5/08 ,  A61B5/20

CPC classification number: A61B5/22 ,  A61B5/0051 ,  A61B5/0066 ,  A61B5/08 ,  A61B5/201 ,  A61B5/441 ,  A61B5/4504 ,  A61B5/4533 ,  A61B5/4538 ,  A61B5/7405

Abstract: A system, devices, and methods are described for imaging and measuring the mechanical properties of both surface and subcutaneous tissues found in living organisms, animals, and in natural and synthetic materials, and may include a first device configured to determine a modulus of a portion of bulk material or subcutaneous tissue (via measurement of vibrations), and/or determine resonant frequency of the vibrations, and a second device operably connected to the first device and configured to generate vibrations. The first device may be an optical coherence tomography device. The system may include a processor and data storage device with instructions which when executed by the processor, cause the processor to process of the frequency data and the displacement data to determine a resonant frequency of the material under investigation and calculate the mechanical modulus of elasticity of the material from a resonance frequency spectrum of the analyzed spectral image.

公开(公告)号：US20240298947A1

公开(公告)日：2024-09-12

申请号：US18039256

申请日：2021-11-30

Applicant: OMINAR INNOVATIONS PRIVATE LIMITED

Inventor： VISHAL ANANDRAO SALUNKHE ,  AMAR SUNIL MORE

IPC: A61B5/20 ,  G01N21/78 ,  G16H10/40

CPC classification number: A61B5/201 ,  A61B5/207 ,  G01N21/78 ,  G16H10/40

Abstract: The present invention relates to a diagnostic device and method for diagnosis thereof for kidney functioning configured for diagnosing one or more ailments associated with the kidneys of a human being. The device comprising of a housing (10A) and a tray (10B). The housing (10A) forms the outer cover in which the tray (10B) is placed. The housing (10A) has a plurality of at least six cavities configured thereon. The tray (10B) is a filter paper printed with a hydrophobic pattern. The device is with the image capturing and image processing unit to process the image to identify the change of colour in reaction zones due to specific biomarkers such as total proteins, creatinine, uric acid, nitrite test, leukocyte esterase (LE), and phosphates. The device is with data interpretation unit to compute the quantitative values.

公开(公告)号：US20240237928A1

公开(公告)日：2024-07-18

申请号：US18583363

申请日：2024-02-21

Applicant: MediBeacon Inc.

Inventor： Kimberly Shultz ,  Jennifer Keating ,  Edward Solomon ,  Kate Bechtel

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/20 ,  G01J1/04 ,  G01J1/44

CPC classification number: A61B5/14556 ,  A61B5/0071 ,  A61B5/201 ,  A61B5/6832 ,  A61B5/7235 ,  A61B5/742 ,  G01J1/0407 ,  G01J1/44 ,  A61B2560/0242 ,  A61B2562/0242

Abstract: A method of assessment of renal function by monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a diffuse reflecting medium with time-varying optical properties is provided that includes using a renal monitoring system comprising at least one light source, at least one light detector, at least one optical filter, and at least one controller to provide a measurement data set comprising a plurality of measurement entries, each measurement data entry comprising at least two measurements obtained at one data acquisition time from a patient before and after administration of the fluorescent agent.

公开(公告)号：US12016691B2

公开(公告)日：2024-06-25

申请号：US16584997

申请日：2019-09-27

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Satoru Suehara ,  Akihiro Takahashi

IPC: A61B5/20 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/208 ,  A61B5/14507 ,  A61B5/201 ,  A61B5/204 ,  A61B5/6852 ,  A61B5/7271 ,  A61B5/743

Abstract: A monitoring system which constitutes an oxygen measurement system includes: an oxygen partial pressure calculation unit that calculates an oxygen partial pressure in urine based on an output signal from the oxygen measurement device; a monitor that displays the oxygen partial pressure calculated by the oxygen partial pressure calculation unit; and a display control unit that changes a format of display of the oxygen partial pressure displayed by the monitor according to the flow rate of urine acquired based on the output signal from the oxygen measurement device.

公开(公告)号：US20240130624A1

公开(公告)日：2024-04-25

申请号：US18398962

申请日：2023-12-28

Applicant: W. L. Gore & Associates, Inc.

Inventor： Christopher J. Vecchio

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/20 ,  A61F2/24 ,  A61L31/10 ,  A61M27/00

CPC classification number: A61B5/02055 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/076 ,  A61B5/14542 ,  A61B5/14552 ,  A61B5/201 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/6847 ,  A61B5/7275 ,  A61B5/742 ,  A61F2/2487 ,  A61L31/10 ,  A61M27/002 ,  A61B5/02158

Abstract: An implantable medical device is disclosed, in which the implantable medical device includes a fluid shunt extending through a wall separating a first cavity and a second cavity within the heart. The fluid shunt includes a first portion adapted to extend into the first cavity within the heart, a second portion adapted to extend into the second cavity within the heart, and an intermediate portion interconnecting the first and second portions. The fluid shunt having a lumen extending between the first and second portions that is adapted to fluidly couple the first and second cavities within the heart. The implantable medical device also includes an occlusion assembly associated with the fluid shunt and adapted to selectively occlude flow through the lumen of the fluid shunt, where the occlusion assembly is activated to adjust flow through the lumen of the fluid shunt, The implantable medical device further includes at least one sensor assembly associated with the first portion of the fluid shunt such that the at least one sensor assembly senses one or more physiologic parameters in the first cavity.

公开(公告)号：US11880980B2

公开(公告)日：2024-01-23

申请号：US16309825

申请日：2017-06-19

Applicant: CHILDREN'S NATIONAL MEDICAL CENTER

Inventor： Marius George Linguraru ,  Juan Jose Cerrolaza ,  Craig Andrew Peters

IPC: G06T7/12 ,  G06T7/13 ,  G06T7/155 ,  G16H50/20 ,  G16H30/40 ,  A61B5/20 ,  A61B5/00 ,  G06T7/00 ,  G06T7/40 ,  G06T7/149 ,  G06F18/214 ,  G06F18/231 ,  G06F18/2411

CPC classification number: G06T7/12 ,  A61B5/201 ,  A61B5/7267 ,  G06F18/214 ,  G06F18/231 ,  G06F18/2411 ,  G06T7/0012 ,  G06T7/13 ,  G06T7/149 ,  G06T7/155 ,  G06T7/40 ,  G16H30/40 ,  G16H50/20 ,  G06T2207/10132 ,  G06T2207/10136 ,  G06T2207/20116 ,  G06T2207/30084

Abstract: Described is a method for segmenting an anatomical part, including identifying a landmark on a contour/surface of a 2D/3D model of the anatomical part in an ultrasound image, assigning a weight to the landmark, identifying different appearance patterns of a region around the landmark based on a previously stored training set; and applying a filter to the different appearance patterns of the region around the landmark in order to identify contours of the anatomical part.

公开(公告)号：US11872363B2

公开(公告)日：2024-01-16

申请号：US17497273

申请日：2021-10-08

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jerry Long ,  Timothy Harrah ,  Aaron Kirkemo ,  Brandon Craft ,  Elizabeth Stokley ,  Sebastian Koerner ,  Chad Schneider

IPC: A61M3/00 ,  A61B17/22 ,  A61M3/02 ,  A61M25/10 ,  A61B5/20 ,  A61M25/00 ,  A61B6/00 ,  A61M39/02 ,  A61B6/12

CPC classification number: A61M3/005 ,  A61B5/201 ,  A61B17/22 ,  A61M3/022 ,  A61M3/0204 ,  A61M3/0208 ,  A61M3/0295 ,  A61M25/0017 ,  A61M25/10 ,  A61B6/12 ,  A61B6/481 ,  A61B6/487 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/22084 ,  A61B2217/005 ,  A61B2217/007 ,  A61M2025/1052 ,  A61M2039/0276 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/3379 ,  A61M2205/50 ,  A61M2210/005 ,  A61M2210/1078 ,  A61M2210/1082 ,  A61M2210/1085 ,  A61M2210/1089

Abstract: Irrigation devices, methods, and systems are disclosed. The system comprises a catheter with one or more lumens and an expandable portion. One or more pumps are used to supply a mixture of contrasting and dilating agents in an interior kidney volume and flush a portion of the mixture out of the interior kidney volume. The method comprises placing a catheter into the interior kidney volume through a ureter, occluding a portion of the ureter with a distal end of the catheter, forming an exit port through an exterior kidney surface, flowing the contrasting and dilating agents through the one or more lumens to supply the mixture in the interior kidney volume, and flushing a portion of the mixture out of the exit port.

公开(公告)号：US20240000350A1

公开(公告)日：2024-01-04

申请号：US18469257

申请日：2023-09-18

Applicant: Medtronic, Inc.

Inventor： John E. Burnes ,  James K. Carney ,  Jonathan L. Kuhn ,  Mark J. Phelps ,  Jesper Svenning Kristensen ,  Rodolphe Katra

IPC: A61B5/1459 ,  A61B5/145 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/1473 ,  A61B5/20 ,  A61N1/375 ,  G01N21/64 ,  A61B5/07

CPC classification number: A61B5/1459 ,  A61B5/14546 ,  A61B5/4833 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/02055 ,  A61B5/4381 ,  A61B5/14735 ,  A61B5/6861 ,  A61B5/7278 ,  A61B5/0071 ,  A61B5/201 ,  A61N1/3756 ,  A61B5/0031 ,  A61B5/686 ,  A61B5/14507 ,  G01N21/6428 ,  A61B5/076 ,  A61B5/0036 ,  A61B5/4839 ,  G01N21/6408 ,  A61B5/08

Abstract: In some examples, a medical system includes a medical device. The medical device may include a housing configured to be implanted in a target site of a patient, a light emitter configured to emit a signal configured to cause a fluorescent marker to emit a fluoresced signal into the target site, and a light detector that may be configured to detect the fluoresced signal. The medical system may include processing circuitry configured to determine a characteristic of the fluorescent marker based on the emitted signal and the fluoresced signal. The characteristic of the fluorescent marker may be indicative of a presence of a compound in the patient, and the processing circuitry may be configured to track the presence of the compound of the patient based on the characteristic of the fluorescent marker.

公开(公告)号：US20230329596A1

公开(公告)日：2023-10-19

申请号：US18212358

申请日：2023-06-21

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/20 ,  A61B5/00 ,  B01D53/22

CPC classification number: A61B5/14552 ,  A61B5/14546 ,  A61B5/201 ,  A61B5/4866 ,  B01D53/228 ,  B01D2259/10

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4−) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.