公开(公告)号：US08231268B2

公开(公告)日：2012-07-31

申请号：US13034214

申请日：2011-02-24

Applicant: Mark F. Krol ,  Thomas C. Moore ,  David A. Pastel ,  Gordon M. Shedd

Inventor： Mark F. Krol ,  Thomas C. Moore ,  David A. Pastel ,  Gordon M. Shedd

IPC: G01K3/00 ,  G01K7/00 ,  G01K11/00 ,  G01K1/00

CPC classification number: G01N35/028 ,  G01J3/453 ,  G01N21/0332 ,  G01N21/553 ,  G01N21/7743 ,  G01N2035/00346 ,  G01N2035/00366

Abstract: A screening device and a method are described herein which can automatically handle and measure (interrogate) a plurality of sensor carriers (i.e., multiwell plates, microplates) with multi-dimensionally arranged, temperature-compensated or temperature-compensatable optical sensors, while maintaining a substantially constant temperature gradient for a relatively long period of time around the optical sensors where temperature compensation has been performed on the sensor carriers.

Abstract translation: 本文描述了一种筛选装置和方法，其可以自动地处理和询问多个传感器载体（即，多孔板，微孔板），其具有多维布置的，温度补偿的或可温度补偿的光学传感器，同时保持 在对传感器载体进行温度补偿的光学传感器周围相当长的周期内的基本恒定的温度梯度。

公开(公告)号：US20120138586A1

公开(公告)日：2012-06-07

申请号：US13245334

申请日：2011-09-26

Applicant: Paul J. L. WEBSTER ,  James M. FRASER ,  Victor X. D. YANG

Inventor： Paul J. L. WEBSTER ,  James M. FRASER ,  Victor X. D. YANG

IPC: B23K26/00

CPC classification number: B23K26/032 ,  A61B18/20 ,  A61B2017/00057 ,  A61B2018/00642 ,  B22F3/105 ,  B22F3/1055 ,  B22F2003/1057 ,  B22F2998/10 ,  B23K1/0056 ,  B23K9/0956 ,  B23K15/0013 ,  B23K15/02 ,  B23K15/08 ,  B23K15/085 ,  B23K26/03 ,  B23K26/20 ,  B23K26/348 ,  B23K26/362 ,  B23K26/382 ,  B23K2103/42 ,  B23K2103/52 ,  B28B1/001 ,  B28B17/0081 ,  B29C64/153 ,  B29C64/386 ,  B33Y30/00 ,  C21D10/00 ,  C22F3/00 ,  G01B9/0203 ,  G01B11/22 ,  G01J3/453 ,  G01N21/84 ,  G01N2021/8416

Abstract: Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser or welding applications. An imaging optical source that produces imaging light. A feedback controller controls at least one processing parameter of the material modification process based on an interferometry output generated using the imaging light. A method of processing interferograms is provided based on homodyne filtering. A method of generating a record of a material modification process using an interferometry output is provided.

Abstract translation: 提供的方法和系统用于在诸如手术激光或焊接应用的材料改性过程的背景下使用光学干涉测量。 产生成像光的成像光源。 基于使用成像光产生的干涉测量输出，反馈控制器控制材料修改过程的至少一个处理参数。 基于零差滤波提供处理干涉图的方法。 提供了使用干涉测量输出来生成材料修改处理的记录的方法。

公开(公告)号：US20120086946A1

公开(公告)日：2012-04-12

申请号：US13154368

申请日：2011-06-06

Applicant: Eric Szarmes ,  Huan Ma

Inventor： Eric Szarmes ,  Huan Ma

IPC: G01J3/45

CPC classification number: G01J3/453 ,  G01J3/1804 ,  G01J3/189

Abstract: A Sagnac interferometer can include a beamsplitter arranged to receive an input beam of light of a design wavelength, to split the input beam of light into first and second beams that counter propagate around an optical path, and to recombine the first and second beams into an output beam of light. The optical path can include at least one diffraction grating that is arranged to satisfy an effective Littrow geometry.

Abstract translation: 萨尼亚克干涉仪可以包括分束器，其布置成接收设计波长的输入光束，以将输入光束分成第一和第二光束，所述第一和第二光束在光路周围传播，并且将第一和第二光束复合到 输出光束。 光路可以包括至少一个被设置为满足有效的Littrow几何形状的衍射光栅。

公开(公告)号：US08144331B2

公开(公告)日：2012-03-27

申请号：US12487454

申请日：2009-06-18

Applicant: Richard G. Lyon ,  David T. Leisawitz ,  Stephen A. Rinehart ,  Nargess Memarsadeghi

Inventor： Richard G. Lyon ,  David T. Leisawitz ,  Stephen A. Rinehart ,  Nargess Memarsadeghi

IPC: G01B9/02 ,  G01J3/45

CPC classification number: G01J3/2823 ,  G01J3/453

Abstract: Disclosed herein are systems, computer-implemented methods, and tangible computer-readable storage media for wide field imaging interferometry. The method includes for each point in a two dimensional detector array over a field of view of an image: gathering a first interferogram from a first detector and a second interferogram from a second detector, modulating a path-length for a signal from an image associated with the first interferogram in the first detector, overlaying first data from the modulated first detector and second data from the second detector, and tracking the modulating at every point in a two dimensional detector array comprising the first detector and the second detector over a field of view for the image. The method then generates a widefield data cube based on the overlaid first data and second data for each point. The method can generate an image from the widefield data cube.

Abstract translation: 本文公开了用于宽场成像干涉测量的系统，计算机实现的方法和有形的计算机可读存储介质。 该方法包括对于图像的视场中的二维检测器阵列中的每个点：从第一检测器收集第一干涉图并从第二检测器收集第二干涉图，调制来自图像相关联的信号的路径长度 利用第一检测器中的第一干涉图，将来自调制的第一检测器的第一数据和来自第二检测器的第二数据重叠，并且在包括第一检测器和第二检测器的二维检测器阵列中的每个点处跟踪调制， 查看图像。 然后，该方法基于覆盖的第一数据和每个点的第二数据生成广域数据立方体。 该方法可以从广域数据立方体生成图像。

公开(公告)号：US07995208B2

公开(公告)日：2011-08-09

申请号：US12537028

申请日：2009-08-06

Applicant: Alex Jacobson ,  Zvi Bleier

Inventor： Alex Jacobson ,  Zvi Bleier

IPC: G01B9/02 ,  G01J3/45 ,  G02B27/10

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/0286 ,  G01J3/453 ,  G02B7/008 ,  G02B7/181 ,  Y10T29/49826

Abstract: A monolithic frame for optics used in interferometers where the material of the monolithic frame may have a substantially different coefficient of thermal expansion from the beamsplitter and compensator without warping, bending or distorting the optics. This is accomplished through providing a securing apparatus holding the optics in place while isolating the expansion thereof from the expansion of the frame. Stability in optical alignment is therefore achieved without requiring a single material or materials of essentially identical coefficients of thermal expansion. The present invention provides stability in situations where it is not possible to utilize a single material for every component of the interferometer.

Abstract translation: 用于干涉仪的光学单片框架，其中整体框架的材料可能具有与分束器和补偿器基本上不同的热膨胀系数，而不会使光学器件翘曲，弯曲或变形。 这通过提供将光学器件保持在适当位置的固定装置来实现，同时隔离其与框架的膨胀的膨胀。 因此，在不需要单一材料或基本上相同的热膨胀系数的材料的情况下实现光学对准的稳定性。 本发明在不可能对干涉仪的每个部件使用单一材料的情况下提供稳定性。

公开(公告)号：US07976217B2

公开(公告)日：2011-07-12

申请号：US11521771

申请日：2006-09-15

Applicant: Mark F. Krol ,  Thomas C. Moore ,  David A. Pastel ,  Gordon M. Shedd

Inventor： Mark F. Krol ,  Thomas C. Moore ,  David A. Pastel ,  Gordon M. Shedd

IPC: G01K3/00

CPC classification number: G01N35/028 ,  G01J3/453 ,  G01N21/0332 ,  G01N21/553 ,  G01N21/7743 ,  G01N2035/00346 ,  G01N2035/00366

Abstract: A screening device and a method are described herein which can automatically handle and measure (interrogate) a plurality of sensor carriers (i.e., multiwell plates, microplates) with multi-dimensionally arranged, temperature-compensated or temperature-compensatable optical sensors, while maintaining a substantially constant temperature gradient for a relatively long period of time around the optical sensors where temperature compensation has been performed on the sensor carriers.

Abstract translation: 本文描述了一种筛选装置和方法，其可以自动地处理和询问多个传感器载体（即，多孔板，微孔板），其具有多维布置的，温度补偿的或可温度补偿的光学传感器，同时保持 在对传感器载体进行温度补偿的光学传感器周围相当长的周期内的基本恒定的温度梯度。

公开(公告)号：US07903253B2

公开(公告)日：2011-03-08

申请号：US12613586

申请日：2009-11-06

Applicant: Jun Koshoubu

Inventor： Jun Koshoubu

IPC: G01B9/02

CPC classification number: G01J3/453 ,  G01J3/2889 ,  G02B21/0096

Abstract: A microscope comprising: a light sampler for collecting light from a measurement area of a sample; a multi-element detector having a plurality of photoelectric elements, for detecting the light collected by the light sampler, each photoelectric element corresponding to a minute measurement region in the measurement area with one-to-one correspondence; a Fourier transform spectrophotometer as a spectroscope; a data sampler for concurrently sampling intensity data sent from each photoelectric element of the multi-element detector at a timing determined by the Fourier transform spectrophotometer; and a data processor for obtaining time-resolved spectrum data for each minute measurement region according to temporally changed interference light data obtained by the data sampler.

Abstract translation: 一种显微镜，包括：用于收集来自样品的测量区域的光的光采样器; 具有多个光电元件的多元件检测器，用于检测由光采样器收集的光，每个光电元件对应于测量区域中的微小测量区域与一一对应; 傅里叶变换分光光度计作为分光镜; 数据采样器，用于在由傅里叶变换分光光度计确定的时刻同时采样从多元素检测器的每个光电元件发送的强度数据; 以及数据处理器，用于根据由数据采样器获得的时间上改变的干涉光数据，为每个微小测量区域获得时间分辨的光谱数据。

公开(公告)号：US07828440B2

公开(公告)日：2010-11-09

申请号：US12453657

申请日：2009-05-18

Applicant: Gholam A. Peyman ,  Shin Yeneya

Inventor： Gholam A. Peyman ,  Shin Yeneya

IPC: A61B3/00 ,  A61B3/02

CPC classification number: A61B3/12 ,  A61B5/14555 ,  G01J3/2823 ,  G01J3/453

Abstract: A method of testing for an ocular disease in an eye includes measuring a condition of the eye to receive a first value, placing an instrument adjacent the surface of the eye, changing the pressure in the eye using the instrument after measuring the condition, measuring the condition of the eye, after changing the pressure, to receive a second value, and comparing the first value to the second value.

Abstract translation: 对眼睛中的眼部疾病进行测试的方法包括测量眼睛接收第一值的状况，将仪器放置在眼睛表面附近，在测量条件之后使用仪器改变眼睛中的压力，测量眼睛 在改变压力之后，接收第二值，并将第一值与第二值进行比较。

公开(公告)号：US20100149542A1

公开(公告)日：2010-06-17

申请号：US12596206

申请日：2008-04-21

Applicant: Börkur Arnvidarson

Inventor： Börkur Arnvidarson

IPC: G01B9/02

CPC classification number: G01B9/02076 ,  G01B9/02068 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0256 ,  G01J3/06 ,  G01J3/453 ,  H01L41/0946 ,  H01L41/0973

Abstract: The invention relates the movement of at least one movable means of an interferometer relative to the body of the interferometer. The system according to the invention, comprises at least two interferometer actuators, that can be operated individually, so that the at least two actuators are capable of moving the at least one movable means of the interferometer. When activating at least one of the at least two interferometer actuators the at least one movable means of the interferometer is moved with a minimum need for correcting for e.g. tilt. In a preferred configuration the system and the method according to the invention comprises three interferometer actuators that can be operated individually.

Abstract translation: 本发明涉及干涉仪的至少一个可移动装置相对于干涉仪的主体的移动。 根据本发明的系统包括可单独操作的至少两个干涉仪致动器，使得至少两个致动器能够移动干涉仪的至少一个可移动装置。 当激活所述至少两个干涉仪致动器中的至少一个时，干涉仪的至少一个可移动装置以最小的需要被移动， 倾斜。 在优选的配置中，根据本发明的系统和方法包括可以单独操作的三个干涉仪致动器。

公开(公告)号：US20100108886A1

公开(公告)日：2010-05-06

申请号：US11155927

申请日：2006-05-18

Applicant: Leslie Brandon Shaw ,  Jasbinder S. Sanghera ,  Ishwar D. Aggarwal

Inventor： Leslie Brandon Shaw ,  Jasbinder S. Sanghera ,  Ishwar D. Aggarwal

IPC: G01J5/02

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/0245 ,  G01J3/0256 ,  G01J3/06 ,  G01J3/453

Abstract: A Fourier-Transform Infrared (FTIR) spectrometer for operation in the mid- and long-wave infrared region (about 2-15 micron wavelengths) is disclosed. The FTIR spectrometer is composed of IR-transmitting fiber and uses a broadband IR source. A fiber stretcher is provided to provide a path difference between a first path and a second path having a sample associated therewith. Stretching of the fiber provides a path difference sufficient to generate an interferogram that can subsequently be analyzed to obtain information about a sample. A method for use of the apparatus of the invention is also disclosed. The method involves stretching of an IR-transmitting fiber to create a path difference sufficient to generate an interferogram. Various aspects of these features enable the construction of compact, portable spectrometers.

Abstract translation: 公开了用于在中长波红外区域（约2-15微米波长）中操作的傅里叶变换红外（FTIR）光谱仪。 FTIR光谱仪由红外发射光纤组成，使用宽带红外线源。 提供纤维拉伸器以提供具有与其相关联的样品的第一路径和第二路径之间的路径差。 纤维的拉伸提供足以产生干涉图的路径差异，随后可以分析干涉图以获得关于样品的信息。 还公开了本发明的装置的使用方法。 该方法涉及拉伸IR发射光纤以产生足以产生干涉图的路径差。 这些特征的各个方面使得能够构造紧凑的便携式光谱仪。