公开(公告)号：US20200372797A1

公开(公告)日：2020-11-26

申请号：US16881230

申请日：2020-05-22

Applicant: MURATA MACHINERY, LTD. ,  OSAKA UNIVERSITY

Inventor： Tatsushi NISHI ,  Kosei NISHIDA ,  Hideki KANAME ,  Kenji KUMAGAI ,  Toshimitsu HIGASHI

IPC: G08G1/123 ,  G01C21/34 ,  B60W60/00

Abstract: A time-space network including a set of state nodes and a set of state transition edges each of which connects between the state nodes, is generated. Each of the state nodes represents a state in which a vehicle is present at a certain point node at a certain time. State transition costs increasing according to a difference of time corresponding to before or after transition and arrival time are defined. In the time-space network, by using the Dijkstra algorithm, a minimum cost transition path in which a sum of the state transition costs is minimum among paths from a starting point state node to any of the state nodes indicating that the vehicle is present at an arrival point is obtained. The starting point state node represents a state that the vehicle is present at a departure point at a reference time. The route and the timing of the vehicle are determined based on the minimum cost transition path.

公开(公告)号：US20200372649A1

公开(公告)日：2020-11-26

申请号：US16766333

申请日：2018-11-05

Applicant: OSAKA UNIVERSITY

Inventor： Kazuaki NAKANE ,  Hirofumi YAMAMOTO ,  Mizuho NISHIO

IPC: G06T7/00 ,  G06T7/136 ,  G06T7/187 ,  G06T7/11

Abstract: In order to assess, with high accuracy, a degree of a change having occurred in a structure, the present invention includes: a Betti number calculating section (42) configured to (I) generate, with respect to a single captured image obtained by capturing an image of a structure, a plurality of binarized images having respective binarization reference values different from each other and (II) calculate, for each of the plurality of binarized images, a first characteristic numerical value indicative of the number of connected regions each of which is obtained by connecting pixels each having one of pixel values obtained by binarization; and a prediction score determining section (44) configured to determine, in accordance with a result of a comparison, information on a change having occurred in the structure, the comparison having been made between (i) a pattern indicative of a relationship between (a) the respective binarization reference values and (b) the first characteristic numerical value and (ii) a predetermined reference pattern.

公开(公告)号：US20200372427A1

公开(公告)日：2020-11-26

申请号：US16881229

申请日：2020-05-22

Applicant: MURATA MACHINERY, LTD. ,  OSAKA UNIVERSITY

Inventor： Tatsushi Nishi ,  Kosei Nishida ,  Hideki Kaname ,  Kenji Kumagai ,  Toshimitsu Higashi

IPC: G06Q10/06 ,  G05D1/02

Abstract: A transport task allocation method includes provisionally allocating a transport task to a set of traveling carriages, determining travel schedules of the traveling carriages, computing a task evaluation value with respect to the transport task allocated to the traveling carriage that travels according to the travel schedule and an overall allocations evaluation value with respect to overall allocations, changing the currently allocated traveling carriage for at least one transport task based on the task evaluation value, and determining overall allocations corresponding to a best overall allocations evaluation value that satisfies a predetermined condition.

公开(公告)号：US20200330459A1

公开(公告)日：2020-10-22

申请号：US16089842

申请日：2017-04-05

Applicant: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET LA RECHERCHE MÉDICALE) ,  UNIVERSITÉ PARIS-EST CRÉTEIL VAL DE MARNE ,  ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) ,  OSAKA UNIVERSITY

Inventor： Geneviève DERUMEAUX ,  Daigo SAWAKI ,  Gabor CZIBIK ,  Takehiko YOSHIMITSU

IPC: A61K31/4985 ,  C12N15/113 ,  A61K39/395 ,  A61P9/00 ,  A61P3/00

Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. The inventors identified osteopontin (OPN) as a critical mediator of adipose tissue remodeling and senescence in obesity and extends this observation to related co-morbidities such as cardiomyopathy. Said result raises the possibility that inhibition of OPN activity may be of value in the prevention of cardiometabolic disease, in particular metabolic cardiomyopathy for which no specific treatment is yet available. In particular, the present invention relates to a method of treating an age-related cardiometabolic disease in an elderly subject in need thereof comprising administering to the subject a therapeutically effective amount of an osteopontin (OPN) inhibitor.

公开(公告)号：US20200318968A1

公开(公告)日：2020-10-08

申请号：US16753192

申请日：2018-07-25

Applicant: TOKYO INSTITUTE OF TECHNOLOGY ,  OSAKA UNIVERSITY ,  JAPAN AVIATION ELECTRONICS INDUSTRY, LIMITED ,  MITSUBISHI HEAVY INDUSTRIES, LTD.

Inventor： Mikio KOZUMA ,  Ryotaro INOUE ,  Takashi MUKAIYAMA ,  Seiichi MORIMOTO ,  Kazunori YOSHIOKA ,  Atsushi TANAKA ,  Yuichiro KAMINO

IPC: G01C19/72

Abstract: A gyroscope of the present invention includes a moving standing light wave generator to generate three moving standing light waves, an atomic beam source to continuously generate an atomic beam in which individual atoms are in the same state, an interference device that exerts a Sagnac effect through interaction between the atomic beam and the three moving standing light waves, and a monitor to detect angular velocity or acceleration by monitoring an atomic beam from the interference device. Each moving standing light wave satisfies an n-th order Bragg condition, where n is a positive integer of 2 or more.

公开(公告)号：US10794899B2

公开(公告)日：2020-10-06

申请号：US15529936

申请日：2015-11-27

Applicant: FUJIFILM WAKO PURE CHEMICAL CORPORATION ,  OSAKA UNIVERSITY

Inventor： Takahiro Nishibu ,  Naoko Imawaka ,  Ken Naruse ,  Rikinari Hanayama

IPC: G01N33/50 ,  C07K1/14 ,  C07K17/02 ,  G01N33/543 ,  G01N33/68 ,  C12N15/09 ,  C07K17/00 ,  C12N7/02 ,  C07K14/705 ,  G01N33/53 ,  G01N15/00 ,  G01N15/10 ,  G01N15/14

Abstract: The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.

公开(公告)号：US20200276302A1

公开(公告)日：2020-09-03

申请号：US16870354

申请日：2020-05-08

Applicant: OSAKA UNIVERSITY ,  CHUGAI SEIYAKU KABUSHIKI KAISHA

Inventor： Atsushi Kumanogoh ,  Ryusuke Omiya ,  Hiroyuki Tsunoda ,  Takeshi Baba ,  Sachiyo Suzuki ,  Yuri Teranishi

IPC: A61K39/395 ,  C07K16/28 ,  C07K16/46 ,  C12N15/09

Abstract: Provided is a novel anti-Plexin-A1 agonist antibody that promotes dendritic cell contraction. Also provided is a pharmaceutical composition comprising such an antibody and a pharmaceutically acceptable carrier.

公开(公告)号：US10755920B2

公开(公告)日：2020-08-25

申请号：US15221153

申请日：2016-07-27

Applicant: OSAKA UNIVERSITY ,  FUJI ELECTRIC CO., LTD.

Inventor： Heiji Watanabe ,  Takayoshi Shimura ,  Takuji Hosoi ,  Mitsuru Sometani

IPC: H01L21/02 ,  C23C8/80 ,  C23C8/10 ,  H01L49/02 ,  H01L29/66 ,  C23C16/455 ,  C23C16/458 ,  C23C16/46 ,  C23C16/52 ,  H01L21/04 ,  H01L29/16

Abstract: A method for manufacturing a semiconductor device includes: thermally-oxidizing a surface of a to-be-processed base made by SiC as body material to form a silicon dioxide film, by supplying gas containing oxidation agent to the surface of the to-be-processed base; exchanging ambient gas containing the oxidation agent after forming the silicon dioxide film, by decreasing a partial pressure of the oxidation agent in the ambient gas to 10 Pa or less; and after exchanging the ambient gas, lowering a temperature of the to-be-processed base.

公开(公告)号：US20200263317A1

公开(公告)日：2020-08-20

申请号：US16783229

申请日：2020-02-06

Applicant: OSAKA UNIVERSITY ,  Panasonic Corporation

Inventor： Yusuke MORI ,  Masayuki IMANISHI ,  Masashi YOSHIMURA ,  Kousuke MURAKAMI ,  Shinsuke KOMATSU ,  Masahiro TADA ,  Yoshio OKAYAMA

IPC: C30B19/12 ,  C30B19/02 ,  C30B29/40

Abstract: A method of manufacturing a group-III nitride crystal includes: a seed crystal preparation step of preparing a plurality of dot-shaped group-III nitrides on a substrate as a plurality of seed crystals for growth of a group-III nitride crystal; and a crystal growth step of bringing surfaces of the seed crystals into contact with a melt containing an alkali metal and at least one group-III element selected from gallium, aluminum, and indium in an atmosphere containing nitrogen and thereby reacting the group-III element with the nitrogen in the melt to grow the group-III nitride crystal.

公开(公告)号：US10744719B2

公开(公告)日：2020-08-18

申请号：US15854051

申请日：2017-12-26

Applicant: HIROTEC CORPORATION ,  OSAKA UNIVERSITY

Inventor： Kiminori Washika ,  Yousuke Kawahito

IPC: B29C65/16 ,  B32B15/08 ,  B29C65/00 ,  B29C65/82 ,  B29C65/44

Abstract: A direct bonding method of metal and resin comprises a first step where the metal material is subjected to electrolytic treatment by using a carboxylic acid to form a new surface, which is then coated with the carboxylic acid to obtain a carboxylic acid-coated metal material; a second step where the resin material and the carboxylic acid-coated metal material are laminated to form an interface to be bonded; a third step where the interface is heated to Tg of the resin material or higher by heating means to remove water from the interface, the decomposition of the resin material generates a carboxyl group, and the new surface is exposed on the surface of the carboxylic acid-coated metal material by removal of the carboxylic acid; and a fourth step where the interface is cooled below the Tg to form a bonded part by bonding the carboxyl group and the new surface.