公开(公告)号：US20080030712A1

公开(公告)日：2008-02-07

申请号：US11809208

申请日：2007-05-31

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Viktor Slobodyan ,  Anatoly Skirda ,  Paul Schilling ,  Anna Pilipchenko ,  Paul Kraus ,  Katherine Sanville ,  Joseph Erickson

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Viktor Slobodyan ,  Anatoly Skirda ,  Paul Schilling ,  Anna Pilipchenko ,  Paul Kraus ,  Katherine Sanville ,  Joseph Erickson

IPC: G01J3/00

CPC classification number: G01N21/8507 ,  G01N21/6402 ,  G01N33/18

Abstract: An ultraviolet (UV) fluorometric sensor measures a chemical concentration in a sample based on the measured fluorescence of the sample. The sensor includes a controller, at least one UV light source, and at least one UV detector. The sensor emits UV light in a wavelength range of 245-265 nm from the light source through the sample in an analytical area. The UV detector measures the fluorescence emission from the sample. The controller transforms output signals from the UV detector into fluorescence values or optical densities for one or more wavelengths in the wavelength range of 265-340 nm. The controller calculates the chemical concentration of the chemical in the sample based on the measured fluorescence emissions.

Abstract translation: 紫外线（UV）荧光传感器基于样品的测量荧光测量样品中的化学浓度。 传感器包括控制器，至少一个UV光源和至少一个UV检测器。 传感器在分析区域内通过样品从光源发射波长245-265nm的紫外光。 UV检测器测量样品的荧光发射。 控制器将来自UV检测器的输出信号转换为在波长范围为265-340nm的一个或多个波长的荧光值或光密度。 控制器基于测量的荧光发射计算样品中化学品的化学浓度。

公开(公告)号：US07198755B2

公开(公告)日：2007-04-03

申请号：US10241451

申请日：2002-09-12

Applicant: Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

Inventor： Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

IPC: G01N21/00 ,  G01N21/75 ,  G01N21/62 ,  G01N21/76 ,  B32B5/02

CPC classification number: G01N21/8507 ,  G01N21/15 ,  G01N21/274 ,  G01N21/276 ,  G01N21/645 ,  G01N33/1886 ,  G01N2021/6417 ,  G01N2021/6421 ,  G01N2021/6478 ,  G01N2201/0218 ,  G01N2201/024 ,  G01N2201/0627 ,  G01N2201/0693 ,  Y10T436/11

Abstract: A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module has one or several excitation channels and one or several emission channels that use a mutual focusing system. To increase efficiency, the excitation and emission channels each have a micro-collimator made with one or more ball lenses. Each excitation channel has a light emitting diode and an optical filter. Each emission channel has a photodiode with a preamplifier and an optical filter. The electronic module connects directly to the optical module and includes a lock-in amplifier, a power supply and a controller with an A/D converter and a connector. The calibrator provides a response proportional to the excitation intensity, and matches with spectral parameter of fluorescence for the analyzed fluorescent substance.

Abstract translation: 多通道氟传感器包括光学模块和组合在具有水下连接器的防水壳体中的电子模块。 氟传感器具有用于氟传感器周期灵敏度验证的积分校准器。 光学模块具有一个或多个激发通道和使用相互聚焦系统的一个或多个发射通道。 为了提高效率，激发和发射通道各自具有由一个或多个球透镜制成的微型准直器。 每个激励通道都有一个发光二极管和一个滤光器。 每个发射通道具有带有前置放大器和光学滤波器的光电二极管。 电子模块直接连接到光模块，包括锁定放大器，电源和带有A / D转换器和连接器的控制器。 校准器提供与激发强度成比例的响应，并与分析的荧光物质的荧光光谱参数相匹配。

公开(公告)号：US20130293881A1

公开(公告)日：2013-11-07

申请号：US13464508

申请日：2012-05-04

Applicant: Eugene TOKHTUEV ,  Christopher J. OWEN ,  Anatoly SKIRDA ,  William M. CHRISTENSEN

Inventor： Eugene TOKHTUEV ,  Christopher J. OWEN ,  Anatoly SKIRDA ,  William M. CHRISTENSEN

IPC: G01N21/05 ,  G01N21/64

CPC classification number: G01N21/15 ,  B08B3/02 ,  B08B5/02 ,  G01N21/05 ,  G01N21/645 ,  G01N2021/151 ,  G01N2021/6478 ,  G01N2021/6482 ,  G01N2201/0639 ,  G02B27/0006

Abstract: An optical sensor may include a sensor head that has an optical window for directing light into a flow of fluid and/or receiving optical energy from the fluid. The optical sensor may also include a flow chamber that includes a housing defining a cavity into which the sensor head can be inserted. In some examples, the flow chamber includes an inlet port defining a flow nozzle that is configured to direct fluid entering the flow chamber against the optical window of the sensor head. In operation, the force of the incoming fluid impacting the optical window may prevent fouling materials from accumulating on the optical window.

公开(公告)号：US20120275259A1

公开(公告)日：2012-11-01

申请号：US13543596

申请日：2012-07-06

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko

IPC: B01F15/02

CPC classification number: G01N35/00 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0481 ,  B01L2400/0638 ,  F04B19/006 ,  G01N21/0332 ,  G01N21/05 ,  G01N35/1097 ,  G01N2021/0346 ,  G01N2035/00237 ,  Y10T436/15 ,  Y10T436/206664 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A microflow analytical system includes a laminate pump assembly connectable with one or more sources of fluid, one or more pneumatic control pumps, a mixer, and a sensor. The laminate pump assembly is adapted to deliver predetermined volumes of the fluid(s) through a plurality of flow paths which are formed within layers of the assembly. Each flow path can include an inlet valve, a pump valve, and an outlet valve each of which are controllable by the pneumatic control pumps. A series of manifolds can be formed within the layers of the pump assembly to provide for simultaneous activation of selected flow paths. Delivered fluid volumes can be mixed in the mixer which, in some embodiments, may be integral with the laminate pump assembly. The sensor can measure one or more characteristics of the mixed fluids to determine one or more properties of the fluids.

Abstract translation: 微流分析系统包括可与一个或多个流体源连接的层压泵组件，一个或多个气动控制泵，混合器和传感器。 层压泵组件适于通过形成在组件的层内的多个流动路径输送预定体积的流体。 每个流动路径可包括入口阀，泵阀和出口阀，每个阀可由气动控制泵控制。 可以在泵组件的层内形成一系列歧管以提供选择的流动路径的同时激活。 输送的流体积可以混合在混合器中，在一些实施例中，该混合器可以与层压泵组件成一体。 传感器可以测量混合流体的一个或多个特性以确定流体的一个或多个特性。

公开(公告)号：US08191703B2

公开(公告)日：2012-06-05

申请号：US12708067

申请日：2010-02-18

Applicant: Eugene Tokhtuev ,  Joseph P. Erickson ,  Christopher J. Owen ,  Paul S. Schilling

Inventor： Eugene Tokhtuev ,  Joseph P. Erickson ,  Christopher J. Owen ,  Paul S. Schilling

IPC: B65G43/00

CPC classification number: B65G43/02

Abstract: Methods for initiating one or more maintenance procedures on a conveyer system employ a load cell assembly that is supported by a link of a conveyor chain of the system in order to collect tension measurements. According to preferred methods, one or more threshold values for a rate of change in tension along particular portions of a circuit, around which the chain is driven, and/or for a variation in tension profile, from one cycle to another around the circuit, are established for comparison with tension measurements that are collected and/or processed by the load cell assembly, in order to detect operating issues and initiate the appropriate maintenance procedure(s). According to some methods, plots of the rate of change of tension versus time are generated and displayed for an operator to view.

Abstract translation: 在输送系统上启动一个或多个维护程序的方法采用称重传感器组件，该称重传感器组件由系统的传送链的链接支撑，以便收集张力测量值。 根据优选的方法，沿着电路周围的特定部分（链条被驱动）和/或用于张力轮廓的变化的张力变化率从循环周围的一个循环到另一周期的一个或多个阈值， 被建立用于与由称重传感器组件收集和/或处理的张力测量值进行比较，以便检测操作问题并启动适当的维护程序。 根据一些方法，产生并显示张力与时间的变化率的图，以供操作者查看。

公开(公告)号：US08084756B2

公开(公告)日：2011-12-27

申请号：US13175491

申请日：2011-07-01

Applicant: Eugene Tokhtuev ,  Christopher J. Owen ,  Viktor Slobodyan ,  Anatoly Skirda ,  Paul Schilling ,  Anna Pilipchenko ,  Paul R. Kraus ,  Katherine M. Sanville ,  Joseph Phillip Erickson

Inventor： Eugene Tokhtuev ,  Christopher J. Owen ,  Viktor Slobodyan ,  Anatoly Skirda ,  Paul Schilling ,  Anna Pilipchenko ,  Paul R. Kraus ,  Katherine M. Sanville ,  Joseph Phillip Erickson

IPC: G01N21/64 ,  G01J1/42 ,  G01N21/49

CPC classification number: G01N21/8507 ,  G01N21/6402 ,  G01N33/18

Abstract: An ultraviolet (UV) fluorometric sensor measures a chemical concentration in a sample based on the measured fluorescence of the sample. The sensor includes a controller, at least one UV light source, and at least one UV detector. The sensor emits UV light in a wavelength range of 245-265 nm from the light source through the sample in an analytical area. The UV detector measures the fluorescence emission from the sample. The controller transforms output signals from the UV detector into fluorescence values or optical densities for one or more wavelengths in the wavelength range of 265-340 nm. The controller calculates the chemical concentration of the chemical in the sample based on the measured fluorescence emissions.

Abstract translation: 紫外线（UV）荧光传感器基于样品的测量荧光测量样品中的化学浓度。 传感器包括控制器，至少一个UV光源和至少一个UV检测器。 传感器在分析区域内通过样品从光源发射波长245-265 nm的紫外光。 UV检测器测量样品的荧光发射。 控制器将来自UV检测器的输出信号转换为在波长范围为265-340nm的一个或多个波长的荧光值或光密度。 控制器基于测量的荧光发射计算样品中化学品的化学浓度。

公开(公告)号：US20110240887A1

公开(公告)日：2011-10-06

申请号：US12750822

申请日：2010-03-31

Applicant: William M. Christensen ,  Eugene Tokhtuev ,  Brian Philip Carlson ,  Paul R. Kraus ,  Benedict F. Pesigan ,  Jill Marie Klegin ,  Adrian Eugene Hartz ,  Michael Patrick Kremer

Inventor： William M. Christensen ,  Eugene Tokhtuev ,  Brian Philip Carlson ,  Paul R. Kraus ,  Benedict F. Pesigan ,  Jill Marie Klegin ,  Adrian Eugene Hartz ,  Michael Patrick Kremer

IPC: G01J1/58 ,  G01J3/00

CPC classification number: G01J1/02 ,  G01J1/0219 ,  G01J1/0233 ,  G01J1/0271 ,  G01N21/645 ,  G01N21/8507 ,  G01N2201/0221

Abstract: Embodiments provide a handheld fluorometer and method of determining a concentration of a product within a sample. In some cases the handheld fluorometer includes an immersible sensor head that measures a fluorescence of the product and a controller that calculates the concentration of product. In some cases the handheld fluorometer includes a handheld controller module, an immersible sensor head connected to the controller module, a sample cup for containing a water sample, and a fastener that removably fastens the sample cup about the immersible sensor head. In some cases the sensor head is angled with respect to the controller module and the fluorometer provides a substantially stable base. The sample cup can be removed to acquire a sample of water containing the product and then refastened about the sensor head for determining the concentration.

Abstract translation: 实施例提供了一种手持荧光计和确定样品中产品浓度的方法。 在某些情况下，手持荧光计包括一个可测量产品荧光的浸入式传感头，以及计算产品浓度的控制器。 在某些情况下，手持式荧光计包括手持控制器模块，连接到控制器模块的浸入式传感器头，用于容纳水样的样品杯和可拆卸地将样品杯紧固在浸没式传感器头周围的紧固件。 在某些情况下，传感器头相对于控制器模块成角度，并且荧光计提供基本稳定的基座。 可以取出样品杯以获取含有产品的水样品，然后围绕传感器头重新固定以确定浓度。

公开(公告)号：US20110070654A1

公开(公告)日：2011-03-24

申请号：US12565520

申请日：2009-09-23

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  William Christensen

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  William Christensen

IPC: G01N33/00

CPC classification number: G01N35/1097 ,  B01L3/502 ,  B01L3/502738 ,  Y10T436/10 ,  Y10T436/111666 ,  Y10T436/15 ,  Y10T436/201666 ,  Y10T436/206664 ,  Y10T436/2575

Abstract: A lab on a valve analytical system includes a rotary sample preparation assembly having a stator and a rotor. The rotor includes a plurality of integral syringe pumps which can be aligned with passages formed within the stator. The stator passages can be connected with fluid inlet connector which connect the sample preparation assembly with fluid sources, and fluid outlet connectors which connect the sample preparation assembly with one or more wet chemical analytical devices. Some embodiments can include a mixer and optical sensor connected with the fluid outlets. One or more drive motors can be used to control simultaneous actuation of one or more of the syringe pumps, thereby providing for simultaneous delivery of metered volumes of fluid.

Abstract translation: 阀门分析系统的实验室包括具有定子和转子的旋转样品制备组件。 转子包括可与定子内形成的通道对准的多个整体式注射泵。 定子通道可以与将样品制备组件与流体源连接的流体入口连接器和将样品制备组件与一个或多个湿化学分析装置连接的流体出口连接器连接。 一些实施例可以包括与流体出口连接的混合器和光学传感器。 可以使用一个或多个驱动马达来控制一个或多个注射器泵的同时致动，由此提供计量体积的流体的同时输送。

公开(公告)号：US20090262351A1

公开(公告)日：2009-10-22

申请号：US12428738

申请日：2009-04-23

Applicant: Joseph Erickson ,  Eugene Tokhtuev ,  Christopher Owen

Inventor： Joseph Erickson ,  Eugene Tokhtuev ,  Christopher Owen

IPC: G01N21/25

CPC classification number: A61M5/1684 ,  A61M2205/3313 ,  G01N21/85 ,  G01N2021/3133 ,  G01N2021/3148 ,  G01N2021/3181 ,  G01N2201/0627

Abstract: An optical detection sensor detects presence or absence of a product within a fluid delivery medium. An emitter directs radiation into the fluid delivery medium and detectors detect transmitted light at a plurality of wavelengths. The output of each detector and combinations of outputs of multiple detectors are associated with at least one out-of-product threshold. In addition, a color ratio is established. A controller compares the detector outputs and combination outputs with the associated out-of-product threshold(s). If any of the thresholds are satisfied, the controller compares the color ratio with an associated out-of-product threshold to verify an out-of-product event has occurred and reduce errors due to batch-to-batch variation of the product. The sensor is able to determine presence or absence of a variety of products having different color, transparency or turbidity.

Abstract translation: 光学检测传感器检测流体输送介质内的产品的存在或不存在。 发射器将辐射器引导到流体输送介质中，并且检测器检测多个波长的透射光。 每个检测器的输出和多个检测器的输出的组合与至少一个产品外阈值相关联。 另外，建立了颜色比。 控制器将检测器输出和组合输出与相关的产品外阈值进行比较。 如果满足任何阈值，则控制器将颜色比与相关的产品外阈值进行比较，以验证产品外部事件已发生，并减少由于产品的批次间变化引起的错误。 传感器能够确定具有不同颜色，透明度或浊度的各种产品的存在或不存在。

公开(公告)号：US20090212236A1

公开(公告)日：2009-08-27

申请号：US12436593

申请日：2009-05-06

Applicant: Eugene Tokhtuev ,  Christopher J. Owen ,  Viktor Slobodyan ,  Anatoly Skirda ,  Paul Schilling ,  Anna Pilipchenko ,  Paul R. Kraus ,  Katherine M. Sanville ,  Joseph Phillip Erickson

Inventor： Eugene Tokhtuev ,  Christopher J. Owen ,  Viktor Slobodyan ,  Anatoly Skirda ,  Paul Schilling ,  Anna Pilipchenko ,  Paul R. Kraus ,  Katherine M. Sanville ,  Joseph Phillip Erickson

IPC: G01N21/64

CPC classification number: G01N21/8507 ,  G01N21/6402 ,  G01N33/18

Abstract: An ultraviolet (UV) fluorometric sensor measures a chemical concentration in a sample based on the measured fluorescence of the sample. The sensor includes a controller, at least one UV light source, and at least one UV detector. The sensor emits UV light in a wavelength range of 245-265 nm from the light source through the sample in an analytical area. The UV detector measures the fluorescence emission from the sample. The controller transforms output signals from the UV detector into fluorescence values or optical densities for one or more wavelengths in the wavelength range of 265-340 nm. The controller calculates the chemical concentration of the chemical in the sample based on the measured fluorescence emissions.

Abstract translation: 紫外线（UV）荧光传感器基于样品的测量荧光测量样品中的化学浓度。 传感器包括控制器，至少一个UV光源和至少一个UV检测器。 传感器在分析区域内通过样品从光源发射波长245-265 nm的紫外光。 UV检测器测量样品的荧光发射。 控制器将来自UV检测器的输出信号转换为在波长范围为265-340nm的一个或多个波长的荧光值或光密度。 控制器基于测量的荧光发射计算样品中化学品的化学浓度。