公开(公告)号：US09127054B2

公开(公告)日：2015-09-08

申请号：US13992567

申请日：2011-12-05

Applicant: Michimoto Kobayashi ,  Yoshinori Tanaka ,  Aiko Takayama ,  Satoko Kanamori ,  Giman Jung ,  Yoshiharu Sakai ,  Hiroshi Okabe

Inventor： Michimoto Kobayashi ,  Yoshinori Tanaka ,  Aiko Takayama ,  Satoko Kanamori ,  Giman Jung ,  Yoshiharu Sakai ,  Hiroshi Okabe

IPC: C07K16/18 ,  G01N33/577 ,  G01N33/574

CPC classification number: C07K16/18 ,  C07K2317/34 ,  G01N33/57446 ,  G01N33/577

Abstract: An object of the present invention is to realize an antibody or a fragment thereof specifically recognizing a cofilin 1 protein, and a method for detecting and testing gastrointestinal cancer with high detection performance, which comprises performing immunoassay of the cofilin 1 protein using the antibody or a fragment thereof. An immunoassay of cofilin 1 protein is characterized by measuring cofilin 1 or a fragment thereof in a sample using 2 or more types of anti-cofilin 1 monoclonal antibody or fragments thereof specifically recognizing different peptide regions in the amino acid sequence constituting the cofilin 1 protein.

Abstract translation: 本发明的目的是实现特异性识别椰子蛋白1蛋白的抗体或其片段，以及检测和检测具有高检测性能的胃肠癌的方法，其包括使用抗体或免疫球蛋白进行免疫测定 片段。 使用两种或更多种类型的抗-cofilin1单克隆抗体或其片段特异性识别构成所述辅酶1蛋白的氨基酸序列中的不同肽区域的方法，对样品中的菲菲林1或其片段进行测定。

公开(公告)号：US08391821B2

公开(公告)日：2013-03-05

申请号：US11444398

申请日：2006-06-01

Applicant: Hiroshi Okabe

Inventor： Hiroshi Okabe

IPC: H04B1/26

CPC classification number: H04B1/38 ,  H01L2223/6677 ,  H01L2224/16227 ,  H01L2924/15192 ,  H01L2924/15313 ,  H01L2924/16152 ,  H01L2924/19105

Abstract: In a radio frequency circuit for multi-mode operation on which multiple transceivers complying with multiple communication systems are disposed, signal interference between circuits is reduced. The PA 222, and the output matching networks 223a and 223b of GSM system, which are circuits independent of the circuit operation of W-CDMA, are disposed in a section of the shortest distance between the PA 121 that handles RF transmission signals of W-CDMA being a first communication system, a third output matching network and an isolator, and a receiver that handles RF received signal of W-CDMA, and in a section of the shortest distance between the PA 121 and the transmitter 130 of W-CDMA. The PA 222, which is a circuit independent of the circuit operation of W-CDMA, is disposed in a section of the shortest distance between the PA 121 and the inter stage filter 125 of W-CDMA.

Abstract translation: 在多模式操作的射频电路中，配置有多个通信系统的多个收发器，减少了电路之间的信号干扰。 作为与W-CDMA的电路操作无关的电路的GSM系统的PA 222和输出匹配网络223a和223b被布置在处理W-CDMA的RF传输信号的PA 121之间的最短距离的部分中， CDMA是第一通信系统，第三输出匹配网络和隔离器，以及处理W-CDMA的RF接收信号的接收机，以及PA-121与W-CDMA的发射机130之间的最短距离的一部分。 作为与W-CDMA的电路动作无关的电路的PA 222被布置在W-CDMA的PA 121和级间滤波器125之间的最短距离的部分。

公开(公告)号：US20130011865A1

公开(公告)日：2013-01-10

申请号：US13582382

申请日：2011-03-03

Applicant: Michimoto Kobayashi ,  Yoshinori Tanaka ,  Satoko Kanamori ,  Giman Jung ,  Yoshiharu Sakai ,  Hiroshi Okabe

Inventor： Michimoto Kobayashi ,  Yoshinori Tanaka ,  Satoko Kanamori ,  Giman Jung ,  Yoshiharu Sakai ,  Hiroshi Okabe

IPC: G01N33/574 ,  G01N21/64 ,  C07K16/18

CPC classification number: G01N33/57446 ,  C07K14/4702 ,  G01N33/57488

Abstract: It is intended to provide a method for detecting gastric cancer, which is low invasive to a human test subject and has high detection sensitivity and accuracy. The present invention provides a method comprising measuring in vitro the amount of Cofilin 1 protein, a variant thereof, and/or a fragment thereof in a body fluid sample derived from a human test subject, and detecting the presence or absence of gastric cancer affecting the test subject on the basis of the amount, and a kit for gastric cancer diagnosis comprising an antibody capable of specifically binding to the protein.

Abstract translation: 目的在于提供一种检测对人体检测对象侵袭性低，检测灵敏度高，准确度高的胃癌的方法。 本发明提供了一种方法，其包括在体外测定源自人类受检者的体液样品中的Cofilin1蛋白，其变体和/或其片段的量，并检测是否存在影响 基于该量的测试对象，以及包含能够特异性结合蛋白质的抗体的胃癌诊断试剂盒。

公开(公告)号：US07905881B2

公开(公告)日：2011-03-15

申请号：US11459411

申请日：2006-07-24

Applicant: Shinya Masuda ,  Taro Miyazawa ,  Kazunori Taniguchi ,  Hiroshi Okabe

Inventor： Shinya Masuda ,  Taro Miyazawa ,  Kazunori Taniguchi ,  Hiroshi Okabe

IPC: A61B18/18

CPC classification number: A61B18/1445 ,  A61B17/32 ,  A61B17/320092 ,  A61B2018/0019 ,  A61B2018/00589 ,  A61B2018/146 ,  A61N1/328 ,  A61N7/02

Abstract: A surgical instrument has a first grasping member, a second grasping member which is provided to the first grasping member to open and close to the first grasping member, and grasps a living tissue between them, an ultrasonic coagulation-cutting unit which includes an ultrasonic vibrating portion provided in one of the first and second grasping members and connected to an ultrasonic transducer to generate ultrasonic vibration, and a pressing portion provided in the other of the first and second grasping members, and facing the ultrasonic vibrating portion, the pressing portion and the ultrasonic vibrating portion pressing the living tissue between them, and a high-frequency coagulation unit which includes a first electrode provided in the first grasping member, and a second electrode provided in the second grasping member, the first electrode and the second electrodes facing each other to coagulate the living tissue.

Abstract translation: 外科器械具有第一把持部件和第二把持部件，该第二把持部件设置在第一把持部件上，与第一把持部件打开接近，并且夹住第二把持部件之间的生物体组织;超声波凝结切断部件，其包括超声波振动 设置在所述第一和第二把持部件中的一个中并连接到超声波换能器以产生超声波振动的部分，以及设置在所述第一和第二抓握部件中的另一个中并且面向超声波振动部分的按压部分， 超声波振动部，在它们之间按压生物体组织;以及高频凝结单元，其包括设置在第一把持构件中的第一电极和设置在第二把持构件中的第二电极，第一电极和第二电极彼此面对 凝固活组织。

公开(公告)号：US07515879B2

公开(公告)日：2009-04-07

申请号：US11013337

申请日：2004-12-17

Applicant: Hiroshi Okabe ,  Hidetoshi Matsumoto

Inventor： Hiroshi Okabe ,  Hidetoshi Matsumoto

IPC: H04B1/38

CPC classification number: H04B1/38 ,  H01L2224/05554 ,  H01L2224/48227 ,  H01L2224/49111 ,  H01L2224/49171 ,  H01L2924/15184 ,  H01L2924/15192 ,  H01L2924/19105 ,  H01L2924/30111 ,  H05K1/0237 ,  H05K1/0298 ,  H05K2201/093 ,  H05K2201/09663 ,  H05K2201/09972 ,  H01L2924/00

Abstract: An RF circuit module, in which a power amplifier and a transceiver are united, with reduced interference between its electronic circuit blocks, downsized and still having high performance, and with a stable performance not dependent on the ground land structure on the motherboard, is provided. The ground plane 110 for at least a last-stage amplifier 11 of the power amplifier 10 where the greatest power is generated in the whole RF circuit block, that is, the source of generating the greatest noise and heat for the RF circuit block, is isolated from the ground plane for at least one circuit portion of the transceiver 9 including an LNA 51, receiver 52, transmitter 30, and VCO 70. These ground planes are connected to a common ground plane 480 through different connection conductors, respectively.

Abstract translation: 提供了一种RF电路模块，其中功率放大器和收发器组合在一起，其电子电路块之间的干扰减小，尺寸小且仍然具有高性能，并且具有不依赖于主板上的地面结构的稳定性能 。 在整个RF电路块中产生最大功率的功率放大器10的至少最后一级放大器11的接地平面110，即产生RF电路块的最大噪声和热的源是 与收发器9的至少一个电路部分的接地平面隔离，包括LNA 51，接收器52，发射器30和VCO 70.这些接地层分别通过不同的连接导体连接到公共接地层480。

公开(公告)号：US07508283B2

公开(公告)日：2009-03-24

申请号：US11092141

申请日：2005-03-28

Applicant: Tatsuo Itoh ,  Christophe Caloz ,  I-Hsiang Lin ,  Hiroshi Okabe

Inventor： Tatsuo Itoh ,  Christophe Caloz ,  I-Hsiang Lin ,  Hiroshi Okabe

IPC: H01P5/12 ,  H01P5/22

CPC classification number: H01P5/227

Abstract: High-frequency couplers and coupling techniques are described utilizing artificial composite right/left-handed transmission line (CRLH-TL). Three specific forms of couplers are described; (1) a coupled-line backward coupler is described with arbitrary tight/loose coupling and broad bandwidth; (2) a compact enhanced-bandwidth hybrid ring coupler is described with increased bandwidth and decreased size; and (3) a dual-band branch-line coupler that is not limited to a harmonic relation between the bands. These variations are preferably implemented in a microstrip fabrication process and may use lumped-element components. The couplers and coupling techniques are directed at increasing the utility while decreasing the size of high-frequency couplers, and are suitable for use with separate coupler or couplers integrated within integrated devices.

Abstract translation: 利用人造复合右/左传输线（CRLH-TL）描述高频耦合器和耦合技术。 描述了三种具体形式的耦合器; （1）耦合线反向耦合器被描述为具有任意的紧/松耦合和宽带宽; （2）以增加的带宽和减小的尺寸描述紧凑的增强带宽混合环耦合器; 和（3）双频分支线耦合器，不限于频带之间的谐波关系。 这些变化优选地在微带制造过程中实现，并且可以使用集总元件部件。 耦合器和耦合技术旨在增加效用，同时降低高频耦合器的尺寸，并且适用于集成在集成器件内的单独的耦合器或耦合器。

公开(公告)号：US07460338B2

公开(公告)日：2008-12-02

申请号：US11341240

申请日：2006-01-26

Applicant: Hiroshi Okabe

Inventor： Hiroshi Okabe

IPC: G11B5/48

CPC classification number: G11B5/486

Abstract: Embodiments of the invention enable high-speed data recording on a magnetic recording medium. In one embodiment, a first section is provided at the recording and reproducing circuit IC side of the inter-connect substrate while a second section is provided at the head side and a third section is provided between a position closer to the head than a section crossed by a spring part of the suspension and the head. Then, the characteristic impedance of the third section recording line is set lower than that of the recording line in the second section except for the first and third sections and the wiring distance between the recording line and the reproducing line in the third section is set longer than that between the recording line and the reproducing line in each of the first and second sections. In addition, the output resistance of the recording and reproducing circuit IC is equated with the characteristic impedance of the main FPC recording line.

Abstract translation: 本发明的实施例使得能够在磁记录介质上进行高速数据记录。 在一个实施例中，第一部分设置在连接基板的记录和再现电路IC侧，而第二部分设置在头部侧，并且第三部分设置在距离头部的位置更靠近头部的位置 通过弹簧部分的悬架和头部。 然后，除了第一和第三部分之外，第三部分记录线的特征阻抗被设定为低于第二部分中的记录线的特征阻抗，并且将第三部分中的记录线和再现线之间的布线距离设定得更长 比在第一和第二部分中的每一个中的记录线和再现线之间的距离大。 此外，记录和再现电路IC的输出电阻等于主FPC记录线的特性阻抗。

公开(公告)号：US07446864B2

公开(公告)日：2008-11-04

申请号：US11398763

申请日：2006-04-06

Applicant: Hiroshi Okabe ,  Toshihiko Matsumoto

Inventor： Hiroshi Okabe ,  Toshihiko Matsumoto

IPC: G01N21/00

CPC classification number: G06K9/2036 ,  G01N21/8806 ,  G01N21/94 ,  G01N2021/8825 ,  G06T7/0006 ,  G06T2207/30136

Abstract: A surface of a work to be inspected is irradiated with an illumination unit for a coaxial incident illumination and an illumination unit for an oblique incident illumination driven to take its image by a camera at the same time. Each of the illumination units and comprises light sources emitting color lights R, G and B, respectively. One of the three kinds of light sources is lighted in the illumination unit and one or two of the light sources which are not lighted in the illumination unit are lighted in the illumination unit.

Abstract translation: 用同轴入射照明的照明单元照射要检查的工件的表面，并且照射驱动的照明单元，以通过相机同时拍摄其图像。 每个照明单元包括分别发射彩色光R，G和B的光源。 三种光源中的一种在照明单元中点亮，并且照明单元中未点亮的一个或两个光源在照明单元中点亮。

公开(公告)号：US20070239029A1

公开(公告)日：2007-10-11

申请号：US11695153

申请日：2007-04-02

Applicant: Hiroshi OKABE ,  Eiji MURAKAMI ,  Hiroshi ICHIHASHI ,  Masaru IMOTO ,  Masami OSHIDA

Inventor： Hiroshi OKABE ,  Eiji MURAKAMI ,  Hiroshi ICHIHASHI ,  Masaru IMOTO ,  Masami OSHIDA

IPC: A61B8/14

CPC classification number: A61B17/320092 ,  A61B2017/320093 ,  A61B2017/320095

Abstract: An ultrasonic operating apparatus having an ultrasonic oscillator to generate ultrasonic oscillation, an oscillation transmitting member for transmitting ultrasonic oscillation, which has a proximal end connected to the ultrasonic oscillator, a jaw which grasps a living tissue in a clearance to the distal end of the oscillation transmitting member, a control unit which opens/closes the jaw with respect to the distal end of the oscillation transmitting member, and an instruction unit which detects that the jaw is closed by the control unit, and instructs the ultrasonic oscillator to output oscillation energy to generate ultrasonic oscillation when the jaw is closed.

Abstract translation: 具有产生超声波振荡的超声波振荡器的超声波操作装置，具有与超声波振荡器连接的近端的超声波振荡用的振动传递部件，具有将振动的前端的间隙内的生物体组织夹住的卡爪 发送构件，相对于振动传递构件的远端打开/关闭夹爪的控制单元，以及指示单元，其检测到所述夹爪由所述控制单元闭合，并且指示所述超声波振荡器将振荡能量输出到 当颚关闭时产生超声波振荡。

公开(公告)号：US20070013992A1

公开(公告)日：2007-01-18

申请号：US11446879

申请日：2006-06-05

Applicant: Hiroshi Okabe ,  Yoshitaka Fujii

Inventor： Hiroshi Okabe ,  Yoshitaka Fujii

IPC: G02F1/29

CPC classification number: A61B17/320092 ,  A61B2017/00367 ,  A61B2017/0046 ,  A61B2017/291

Abstract: An ultrasonic treatment switch device includes an adapter, a switch, a switch fixing portion and an adapter fixing portion. The adapter is connected to a power source and having a handpiece fixing portion detachably attached to a handpiece having an ultrasonic transducer. The switch is connected to the power source and causes an electric signal to be output from the power source so that the ultrasonic transducer generates ultrasonic vibrations. The switch fixing portion is provided in the switch and detachably attached to the adapter. The adapter fixing portion is provided in the adapter. The switch fixing portion is attached to the adapter fixing portion.

Abstract translation: 超声处理开关装置包括适配器，开关，开关固定部和适配器固定部。 适配器连接到电源并且具有可拆卸地附接到具有超声波换能器的手持件的手持件固定部。 开关连接到电源，并且从电源输出电信号，使得超声波换能器产生超声波振动。 开关固定部设置在开关中并可拆卸地附接到适配器。 适配器固定部设置在适配器中。 开关固定部附接到适配器固定部。