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公开(公告)号：US20080140191A1
公开(公告)日：2008-06-12
申请号：US12016054
申请日：2008-01-17
Applicant: Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
Inventor： Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
IPC: A61F2/24
CPC classification number: A61F2/2451 , A61B2017/00243 , A61F2/24 , A61F2/2442 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2250/0012 , A61F2310/00017 , A61F2310/00023 , A61N1/057 , A61N2001/0585
Abstract: A device affects the mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart and a second anchor configured to be positioned within the coronary sinus of the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart. The second anchor, when deployed, anchors against distal movement and is moveable in a proximal direction. The device further includes a connecting member having a fixed length permanently attached to the first and second anchors. As a result, when the first and second anchors are within the coronary sinus with the first anchor anchored in the coronary sinus, the second anchor may be displaced proximally to affect the geometry of the mitral valve annulus and released to maintain the effect on the mitral valve geometry.
Abstract translation: 一个装置影响心脏的二尖瓣环几何形状。 该装置包括第一锚定构件，其构造成定位在心脏内邻近心脏二尖瓣环的心脏的冠状窦内并且锚固在心脏周围的第二锚定件上，第二锚固件构造成定位在靠近第一锚固件的心脏的冠状窦内， 心脏内的二尖瓣环。 当第二锚固件被展开时，锚固件抵靠远端运动并且可沿近端方向移动。 该装置还包括具有固定长度的连接构件，该固定长度永久地附接到第一和第二锚固件。 结果，当第一和第二锚固件位于冠状窦内时，第一锚固件锚固在冠状窦中时，第二锚固件可以向近侧位移以影响二尖瓣环的几何形状并被释放以维持对二尖瓣的作用 阀几何。
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公开(公告)号：US07316708B2
公开(公告)日：2008-01-08
申请号：US10313914
申请日：2002-12-05
Applicant: Lucas S. Gordon , Mark L. Mathis , Greg Nieminen
Inventor： Lucas S. Gordon , Mark L. Mathis , Greg Nieminen
IPC: A61F2/06
CPC classification number: A61F2/95 , A61B17/3468 , A61B2017/1205 , A61F2002/9511
Abstract: A system for selectively deploying a medical device includes a cartridge that is engageable with a proximal end of a delivery catheter that is routed to a desired location in a patient's body. An advancement mechanism is provided for advancing the medical device out of the cartridge and into the delivery catheter for deploying the medical device at the desired location in the patient's body.
Abstract translation: 用于选择性地部署医疗装置的系统包括可与输送导管的近端接合的药筒，所述输送导管被路由到患者体内的期望位置。 提供了一种推进机构，用于将医疗装置推出药筒并进入输送导管，以将医疗装置展开在病人身体的所需位置。
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公开(公告)号：US07309354B2
公开(公告)日：2007-12-18
申请号：US10994169
申请日：2004-11-19
Applicant: Mark L. Mathis , Leonard Kowalsky , David G. Reuter , Cruz Beeson
Inventor： Mark L. Mathis , Leonard Kowalsky , David G. Reuter , Cruz Beeson
IPC: A61F2/06
CPC classification number: A61F2/2451 , A61F2/2466 , A61F2002/91591 , A61F2210/0014 , A61F2220/0091 , A61F2230/0023 , A61F2250/0004 , A61F2250/0008 , A61F2250/0012 , A61F2250/0086 , A61F2310/00017 , A61F2310/00023
Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.
Abstract translation: 锚定器将具有细长体的治疗装置锚定在体腔内。 所述锚固件包括承载在所述装置上的固定构件，所述固定构件可从第一构造调节，所述第一构型允许将所述装置放置在所述体腔内到达将所述装置固定在所述体腔内的第二构造。 锚固件还包括将固定构件锁定在第二构造中的锁。 固定构件可以锁定在第一构造和最大第二构造之间的多个中间点中的任何一个中。
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公开(公告)号：US07179282B2
公开(公告)日：2007-02-20
申请号：US10429171
申请日：2003-05-02
Applicant: Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter , Cruz Beeson , Leonard Kowalsky
Inventor： Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter , Cruz Beeson , Leonard Kowalsky
CPC classification number: A61F2/2451 , A61F2250/001 , A61F2250/0059
Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
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公开(公告)号：US06976995B2
公开(公告)日：2005-12-20
申请号：US10066426
申请日：2002-01-30
Applicant: Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
Inventor： Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
CPC classification number: A61F2/2451 , A61B2017/00243 , A61F2/24 , A61F2/2442 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2250/0012 , A61F2310/00017 , A61F2310/00023 , A61N1/057 , A61N2001/0585
Abstract: A device effects the mitral valve annulus geometry of a heart. The device includes first and second anchors configured to be positioned within the coronary sinus of the heart adjacent the mitral valve annulus of the heart and a fixed length connecting member permanently attached to the first and second anchors. With the first anchor anchored in the coronary sinus, the second anchor may be displaced proximally to effect the geometry of the mitral valve annulus and released to maintain the effect on the mitral valve geometry.
Abstract translation: 一个装置影响心脏二尖瓣环的几何形状。 该装置包括第一和第二锚定件，其构造成定位在与心脏的二尖瓣环相邻的心脏的冠状窦内，以及固定长度的连接构件，其永久地附接到第一和第二锚定件。 通过锚固在冠状窦中的第一锚固件，第二锚固件可以向近侧移位以实现二尖瓣环的几何形状并被释放以保持对二尖瓣几何形状的影响。
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Patent Agency Ranking
公开(公告)号：US06960229B2
公开(公告)日：2005-11-01
申请号：US10429181
申请日：2003-05-02
Applicant: Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
Inventor： Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
CPC classification number: A61F2/2451
Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
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公开(公告)号：US06743219B1
公开(公告)日：2004-06-01
申请号：US09631002
申请日：2000-08-02
Applicant: Clifford J. Dwyer , Luis A. Davila , Frederick Feller, III , Mark L. Mathis , David J. Wilson
Inventor： Clifford J. Dwyer , Luis A. Davila , Frederick Feller, III , Mark L. Mathis , David J. Wilson
IPC: A61M2500
Abstract: A delivery apparatus for self-expanding stents may be utilized to safely deliver stents to a target site. The apparatus has an outer sheath forming an elongated tubular member having distal and proximal ends and an inside and outside diameter. The apparatus also includes an inner shaft located coaxially within the outer sheath. The inner shaft has a distal end, a proximal end and a longitudinal axis extending therebetween. At least a portion of the inner shaft is made from a flexible coiled member. The shaft preferably includes a stop attached thereto, the stop being proximal to the distal end of the sheath. Lastly, the apparatus includes a self-expanding stent located within the outer sheath, wherein the stent makes frictional contact with the outer sheath and the shaft is disposed coaxially within a lumen of the stent. During deployment of the stent, the stent makes contact with the stop.
Abstract translation: 用于自扩张支架的输送装置可用于将支架安全地输送到目标部位。 该装置具有形成具有远端和近端以及内径和外径的细长管状构件的外护套。 该装置还包括同轴地位于外护套内的内轴。 内轴具有远端，近端和在其间延伸的纵向轴线。 内轴的至少一部分由柔性卷绕构件制成。 轴优选地包括附接到其上的止动件，止动件靠近护套的远端。 最后，该装置包括位于外护套内的自扩张支架，其中支架与外护套摩擦接触，并且轴同轴地设置在支架内腔内。 在展开支架期间，支架与止动器接触。
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公开(公告)号：US09408695B2
公开(公告)日：2016-08-09
申请号：US12016054
申请日：2008-01-17
Applicant: Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
Inventor： Mark L. Mathis , Gregory D. Nieminen , David G. Reuter
CPC classification number: A61F2/2451 , A61B2017/00243 , A61F2/24 , A61F2/2442 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2250/0012 , A61F2310/00017 , A61F2310/00023 , A61N1/057 , A61N2001/0585
Abstract: A device affects the mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart and a second anchor configured to be positioned within the coronary sinus of the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart. The second anchor, when deployed, anchors against distal movement and is moveable in a proximal direction. The device further includes a connecting member having a fixed length permanently attached to the first and second anchors. As a result, when the first and second anchors are within the coronary sinus with the first anchor anchored in the coronary sinus, the second anchor may be displaced proximally to affect the geometry of the mitral valve annulus and released to maintain the effect on the mitral valve geometry.
Abstract translation: 一个装置影响心脏的二尖瓣环几何形状。 该装置包括第一锚定构件，其构造成定位在心脏内邻近心脏二尖瓣环的心脏的冠状窦内并且锚固在心脏周围的第二锚定件上，第二锚固件构造成定位在靠近第一锚固件的心脏的冠状窦内， 心脏内的二尖瓣环。 当第二锚固件被展开时，锚固件抵靠远端运动并且可沿近端方向移动。 该装置还包括具有固定长度的连接构件，该固定长度永久地附接到第一和第二锚固件。 结果，当第一和第二锚固件位于冠状窦内时，第一锚固件锚固在冠状窦中时，第二锚固件可以向近侧位移以影响二尖瓣环的几何形状并被释放以维持对二尖瓣的作用 阀几何。
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公开(公告)号：US20120172909A1
公开(公告)日：2012-07-05
申请号：US13418534
申请日：2012-03-13
Applicant: Mark L. Mathis , David Thompson , Nathan Aronson , Patrick Wu
Inventor： Mark L. Mathis , David Thompson , Nathan Aronson , Patrick Wu
IPC: A61M29/00
CPC classification number: A61B17/12104 , A61B1/2676 , A61B17/12022 , A61B17/12031 , A61B17/12131 , A61B17/12145 , A61B17/12172 , A61B17/122 , A61B2017/00477 , A61B2017/00809 , A61B2017/1205 , A61B2017/12054 , A61F2/04 , A61F2002/043 , A61M16/04 , A61M16/0406 , A61M16/208 , A61M2205/0266
Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
Abstract translation: 本发明提供改进的医疗装置，治疗处理系统和用于治疗肺的治疗方法。 肺容积减小系统包括可植入装置，其具有细长体，其尺寸和形状用于经由气道系统输送到患者的肺气道。 植入物在植入物处于输送构型中时被插入和定位，并且被重新配置为展开构型，以便局部压缩肺的邻近组织，细长体的一部分通常在气道内侧向移动，以便横向压缩 肺组织。 多个这样的植入物将经常用于治疗患者的肺部。
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公开(公告)号：US08182529B2
公开(公告)日：2012-05-22
申请号：US10945855
申请日：2004-09-20
Applicant: Lucas S. Gordon , Mark L. Mathis , Gregory Nieminen , Leonard Kowalsky , Ryan Braxtan , Brian J. Doll
Inventor： Lucas S. Gordon , Mark L. Mathis , Gregory Nieminen , Leonard Kowalsky , Ryan Braxtan , Brian J. Doll
CPC classification number: A61F2/95 , A61B17/3468 , A61B2017/1205 , A61F2002/9511
Abstract: The invention is a method of delivering and deploying a tissue shaping device in a lumen within a patient, with the tissue shaping device including an anchor. In some embodiments the method includes the steps of: inserting a delivery catheter into the lumen; percutaneously delivering the device to a target site within the lumen through a delivery catheter; operating an actuator to expose an anchor; and operating the actuator to lock the anchor. In other, the method includes the steps of: inserting a delivery catheter into the lumen; moving the device from a cartridge into the delivery catheter; delivering the device to a target site within the lumen; operating an actuator to move the delivery catheter with respect to the anchor to expose the anchor; and expanding the anchor.
Abstract translation: 本发明是一种在组织整形装置中包括锚固件的方式，将组织成形装置递送和展开在患者体内。 在一些实施例中，该方法包括以下步骤：将输送导管插入内腔; 通过输送导管将装置经皮递送到内腔内的目标部位; 操作致动器以暴露锚; 并操作致动器以锁定锚。 另外，该方法包括以下步骤：将输送导管插入内腔; 将装置从药筒移动到输送导管中; 将装置输送到管腔内的目标部位; 操作致动器以使输送导管相对于锚固件移动以暴露锚固件; 并扩大锚点。
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