公开(公告)号：US06359178B1

公开(公告)日：2002-03-19

申请号：US09762798

申请日：2001-02-13

Applicant: Rolf Fischer ,  Peter Bassler ,  Hermann Luyken ,  Frank Ohlbach ,  Johann-Peter Melder ,  Martin Merger ,  Andreas Ansmann ,  Alwin Rehfinger ,  Guido Voit

Inventor： Rolf Fischer ,  Peter Bassler ,  Hermann Luyken ,  Frank Ohlbach ,  Johann-Peter Melder ,  Martin Merger ,  Andreas Ansmann ,  Alwin Rehfinger ,  Guido Voit

IPC: C07C20948

CPC classification number: C07C209/48 ,  C07C211/12

Abstract: A process for catalytic hydrogenation of adiponitrile to hexamethylenediamine at elevated temperature and elevated pressure in the presence of catalysts based on elemental iron as catalytically active component and ammonia as solvent comprises a) hydrogenating adiponitrile at from 70 to 220° C. and from 100 to 400 bar in the presence of catalysts based on elemental iron as catalytically active component and ammonia as solvent to obtain a mixture comprising adiponitrile, 6-aminocapronitrile, hexamethylenediamine and high boilers until the sum total of the 6-aminocapronitrile concentration and the adiponitrile concentration is within the range from 1 to 50% by weight, based on the ammonia-free hydrogenation mixture, b) removing ammonia from the hydrogenation effluent, c) removing hexamethylenediamine from the remaining mixture, d) separating 6-aminocapronitrile and adiponitrile from high boilers individually or together, and e) returning 6-aminocapronitrile, adiponitrile or mixtures thereof into step a).

Abstract translation: 在基于作为催化活性组分的元素铁和作为溶剂的氨的催化剂存在下，在升高的温度和升高的压力下将己二腈催化氢化为己二胺的方法包括在70-220℃和100-400巴下氢化己二腈 在基于作为催化活性成分的元素铁和作为溶剂的氨的催化剂存在下，得到包含己二腈，6-氨基己腈，六亚甲基二胺和高沸点剂的混合物，直到6-氨基己腈浓度和己二腈浓度的总和在范围内 基于无氨氢化混合物，从1至50重量％，b）从氢化流出物中除去氨，c）从剩余的混合物中除去六亚甲基二胺，d）分别或一起从高锅炉中分离6-氨基己腈和己二腈， 和），返回6-氨基己腈，己二腈或其混合物 n步骤a）。

公开(公告)号：US6140545A

公开(公告)日：2000-10-31

申请号：US251462

申请日：1999-02-17

Applicant: Martin Merger ,  Shelue Liang ,  Rolf Fischer ,  Joachim Wulff-Doring

Inventor： Martin Merger ,  Shelue Liang ,  Rolf Fischer ,  Joachim Wulff-Doring

IPC: C07C29/149 ,  C07C37/08

CPC classification number: C07C29/149 ,  C07C2101/14

Abstract: In a process for preparing alcohols by gas phase hydrogenation of carboxylic acids or esters thereof at elevated temperature and elevated pressure in the presence of catalysts consisting of or comprising, as hydrogenating components, oxides of main group VI and/or subgroup IV, the hydrogenation is carried outa) at from 250.degree. C. to 400.degree. C. and from 5 bar to 100 bar in the presence ofb) primary or secondary alcohols, the molar hydrogen/alcohol ratio being at most 800.

Abstract translation: 在通过在升高的温度和升高的压力下，在由主要VI族和/或第IV族的氧化物组成或包含氢化组分的催化剂存在下，在羧酸或其酯的气相氢化制备醇的方法中，氢化是 在b）伯醇或仲醇的存在下，在250℃至400℃和5巴至100巴下进行a），氢/醇摩尔比为至多800。

公开(公告)号：US08912361B2

公开(公告)日：2014-12-16

申请号：US13415466

申请日：2012-03-08

Applicant: Thomas Schaub ,  Boris Buschhaus ,  Marion Kristina Brinks ,  Mathias Schelwies ,  Rocco Paciello ,  Johann-Peter Melder ,  Martin Merger

Inventor： Thomas Schaub ,  Boris Buschhaus ,  Marion Kristina Brinks ,  Mathias Schelwies ,  Rocco Paciello ,  Johann-Peter Melder ,  Martin Merger

IPC: C07C213/02 ,  C07C209/16 ,  C07D307/52 ,  C07D207/20 ,  C07D295/027 ,  C07D205/04 ,  C07D211/06 ,  C07D207/02 ,  C07D223/04

CPC classification number: C07C213/02 ,  C07C209/16 ,  C07C2601/14 ,  C07D205/04 ,  C07D207/02 ,  C07D207/20 ,  C07D211/06 ,  C07D223/04 ,  C07D295/027 ,  C07D307/52 ,  C07C217/08 ,  C07C215/08 ,  C07C211/09 ,  C07C211/10 ,  C07C211/18 ,  C07C215/20 ,  C07C211/12

Abstract: Process for preparing primary amines which have at least one functional group of the formula (—CH2—NH2) and at least one further primary amino group by alcohol amination of starting materials having at least one functional group of the formula (—CH2—OH) and at least one further functional group (—X), where (—X) is selected from among hydroxyl groups and primary amino groups, by means of ammonia with elimination of water, wherein the reaction is carried out homogeneously catalyzed in the presence of at least one complex catalyst comprising at least one element selected from groups 8, 9 and 10 of the Periodic Table and also at least one donor ligand.

Abstract translation: 具有至少一个式（-CH 2 -NH 2）官能团和至少一个另外的伯氨基的伯胺的方法，其通过具有至少一个式（-CH 2 -OH）官能团的原料醇醇胺化， 和至少一个另外的官能团（-X），其中（-X）选自羟基和伯氨基，通过氨除去水，其中反应在存在下进行均匀催化 至少一种复合催化剂，其包含至少一种选自元素周期表第8,9和10族的元素，以及至少一种供体配体。

公开(公告)号：US08637709B2

公开(公告)日：2014-01-28

申请号：US13415174

申请日：2012-03-08

Applicant: Thomas Schaub ,  Boris Buschhaus ,  Marion Kristina Brinks ,  Mathias Schelwies ,  Rocco Paciello ,  Johann-Peter Melder ,  Martin Merger

Inventor： Thomas Schaub ,  Boris Buschhaus ,  Marion Kristina Brinks ,  Mathias Schelwies ,  Rocco Paciello ,  Johann-Peter Melder ,  Martin Merger

IPC: C07C209/16 ,  C07C209/18

CPC classification number: C07C213/02 ,  C07C215/08 ,  C07C217/08

Abstract: Preparing a primary amine by alcohol amination of alcohol with ammonia and elimination of water includes reacting, in a homogeneously catalyzed reaction, a mixture of alcohol, ammonia, nonpolar solvent, and catalyst, in a liquid phase, to obtain a product mixture. The process then includes phase separating the product mixture into a polar product phase and a nonpolar product phase, and separating off the nonpolar product phase. At least some of the nonpolar phase returns to the homogenously catalyzed reaction. The process further includes separating off amination product from the polar product phase. At least some of the catalyst is in the nonpolar phase, and the catalyst accumulates in the nonpolar phase.

Abstract translation: 通过醇与醇的氨基化反应制备伯胺并除去水包括在均相催化的反应中，将醇，氨，非极性溶剂和催化剂的混合物在液相中反应，得到产物混合物。 然后，该方法包括将产物混合物相分离成极性产物相和非极性产物相，并将非极性产物相分离。 至少一些非极性相返回均匀催化反应。 该方法还包括从极性产物相分离胺化产物。 至少一些催化剂处于非极性相，并且催化剂积聚在非极性相中。

公开(公告)号：US07696360B2

公开(公告)日：2010-04-13

申请号：US10515625

申请日：2003-07-07

Applicant: Gerd Kaibel ,  Martin Merger ,  Thomas Domschke ,  Petra Deckert ,  Friedrich Sauer

Inventor： Gerd Kaibel ,  Martin Merger ,  Thomas Domschke ,  Petra Deckert ,  Friedrich Sauer

IPC: C07D307/62

CPC classification number: C07D307/62 ,  Y02P20/582

Abstract: The invention relates to a method for the separation of ascorbic acid from a mixture containing ascorbic acid and 2-keto-L-gulonic acid in a polar, preferably aqueous solvent, by means of liquid/liquid extraction using an amide. The method preferably also comprises steps for the back-extraction of the ascorbic acid, recycling of the extraction solvent and/or the back extraction solvent and for isolation of the ascorbic acid from the back extraction solvent. The invention further relates to a method for the production of ascorbic acid from KGA and isolation of the ascorbic acid so produced.

Abstract translation: 本发明涉及通过使用酰胺的液/液萃取在极性优选含水溶剂中从含有抗坏血酸和2-酮-L-古洛糖酸的混合物中分离抗坏血酸的方法。 该方法优选还包括用于反萃取抗坏血酸的步骤，提取溶剂和/或反萃取溶剂的再循环以及用于从反萃取溶剂中分离抗坏血酸的步骤。 本发明还涉及从KGA生产抗坏血酸并分离如此生产的抗坏血酸的方法。

公开(公告)号：US20070123717A1

公开(公告)日：2007-05-31

申请号：US10582911

申请日：2004-12-10

Applicant: Thomas Domschke ,  Martin Merger ,  Frank Haese ,  Peter Resch ,  Tillmann Faust

Inventor： Thomas Domschke ,  Martin Merger ,  Frank Haese ,  Peter Resch ,  Tillmann Faust

IPC: C07D307/62

CPC classification number: C07C67/08 ,  C07H7/02 ,  C07H7/027 ,  C07C69/716

Abstract: A method for the production of C1-C10-alkyl 2-keto-L-gulonates by esterification of 2-keto-L-gulonic acid anhydrate with an anhydrous C1-C10-alkyl alcohol in the presence of an acidic homogeneous catalyst in a reactor cascade comprising at least two reactors, one of these reactors being a tubular reactor, without the water forming in the esterification being removed from the reaction space.

Abstract translation: 通过2-酮-L-古洛糖酸无水物与无水C的酯化制备C 1 -C 10 - 烷基2-酮-L-古洛糖化物的方法 在酸性均相催化剂存在下，在包含至少两个反应器的反应器级联中，其中一个反应器是管式反应器，没有 酯化反应中形成的水​​从反应空间中除去。

公开(公告)号：US06462220B1

公开(公告)日：2002-10-08

申请号：US09763710

申请日：2001-02-26

Applicant: Hermann Luyken ,  Frank Ohlbach ,  Andreas Ansmann ,  Peter Bassler ,  Rolf Fischer ,  Johann-Peter Melder ,  Martin Merger ,  Alwin Rehfinger ,  Guido Voit ,  Günther Achhammer

Inventor： Hermann Luyken ,  Frank Ohlbach ,  Andreas Ansmann ,  Peter Bassler ,  Rolf Fischer ,  Johann-Peter Melder ,  Martin Merger ,  Alwin Rehfinger ,  Guido Voit ,  Günther Achhammer

IPC: C07C25525

CPC classification number: C07C253/30 ,  C07C209/48

Abstract: A process for the coproduction of 6-aminocapronitrile and hexamethylenediamine starting from adiponitrile by a) hydrogenating adiponitrile in the presence of a catalyst comprising an element of the eighth transition group as catalytically active component, to obtain a mixture comprising 6-aminocapronitrile, hexamethylenediamine, adiponitrile and high boilers, b) distillatively removing hexamethylenediamine from the mixture comprising 6-aminocapronitrile, hexamethylenediamine, adiponitrile and high boilers, and either cl) distillatively removing 6-aminocapronitrile, and then d1) distillatively removing adiponitrile, or c2) simultaneously distillatively removing 6-aminocapronitrile and adiponitrile into separate fractions is characterized by base of column temperatures below 185° C. in steps d1) or c2).

Abstract translation: 一种从己二腈开始共生产6-氨基己腈和六亚甲基二胺的方法，其中a）在包含第八过渡基团的元素的催化剂作为催化活性组分的存在下氢化己二腈，得到包含6-氨基己腈，己二胺，己二腈和 高锅炉，b）从包含6-氨基己腈，己二胺，己二腈和高沸点的混合物中蒸馏除去六亚甲基二胺，并且将蒸馏除去6-氨基己腈，然后d1）蒸馏除去己二腈，或同时蒸馏除去6-氨基己腈和己二腈 分离的馏分以步骤d1）或c2）中塔温度低于185℃的碱为特征。

公开(公告)号：US06362332B1

公开(公告)日：2002-03-26

申请号：US09786914

申请日：2001-03-12

Applicant: Martin Merger ,  Rolf Fischer ,  Andreas Ansmann

Inventor： Martin Merger ,  Rolf Fischer ,  Andreas Ansmann

IPC: C07D22310

CPC classification number: C07D201/02 ,  C07D295/023

Abstract: A cyclic lactam and a cyclic amine are coproduced by reacting an aliphatic alpha, omega-diamine with water in the gas phase in the presence of a heterogeneous catalyst.

Abstract translation: 在非均相催化剂存在下，通过在气相中使脂族α，ω-二胺与水反应来共同制备环状内酰胺和环胺。

公开(公告)号：US06297394B1

公开(公告)日：2001-10-02

申请号：US09622773

申请日：2000-08-23

Applicant: Guido Voit ,  Rolf Fischer ,  Peter Bassler ,  Andreas Ansmann ,  Hermann Luyken ,  Martin Merger ,  Frank Ohlbach ,  Alwin Rehfinger

Inventor： Guido Voit ,  Rolf Fischer ,  Peter Bassler ,  Andreas Ansmann ,  Hermann Luyken ,  Martin Merger ,  Frank Ohlbach ,  Alwin Rehfinger

IPC: C07C20922

CPC classification number: C07C253/30 ,  B01J23/8892 ,  C07C209/48 ,  C07C211/12 ,  C07C255/24

Abstract: A material useful as catalyst for the hydrogenation of alpha, Omega-dinitriles comprises a) iron or a compound based on iron or mixtures thereof, (b) from 0.001 to 0.3% by weight based on (a) of a promoter based on 2, 3, 4 or 5 elements selected from the group consisting of aluminum, silicon, zirconium, titanium and vanadium, (c) from 0 to 0.3% by weight based on (a) of a compound based on an alkali and/or alkaline earth metal, and also (d) from 0.001 to 1% by weight based on (a) of manganese.

Abstract translation: 可用作α，ω-二腈的氢化催化剂的材料包括a）铁或基于铁或其混合物的化合物，（b）基于（a）基于2,3的启动子的0.001至0.3重量％ ，选自铝，硅，锆，钛和钒的4或5种元素，（c）基于（a）基于碱金属和/或碱土金属的化合物，0至0.3重量％ 以及（d）基于（a）锰的0.001至1重量％。

公开(公告)号：US06222059B1

公开(公告)日：2001-04-24

申请号：US09254570

申请日：1999-03-10

Applicant: Klaus Ebel ,  Rolf Fischer ,  Klemens Flick ,  Martin Merger ,  Guido Voit

Inventor： Klaus Ebel ,  Rolf Fischer ,  Klemens Flick ,  Martin Merger ,  Guido Voit

IPC: C07C25504

CPC classification number: C07C255/24 ,  C07C209/48 ,  C07C211/12 ,  C07C253/30

Abstract: A process for preparing aliphatic alpha,omega-amino nitrites by partial hydrogenation of aliphatic alpha,omega-dinitriles in the presence of a catalyst, wherein the catalyst used for the partial hydrogenation comprises (a) iron or a compound based on iron or mixtures thereof and (b) from 0.01 to 5% by weight, based on (a), of a promoter based on 2,3,4 or 5 elements selected from the group consisting of aluminum, silicon, zirconium, titanium and vanadium and (c) from 0 to 5% by weight, based on (a), of a compound based on an alkali metal or alkaline earth metal.

Abstract translation: 在催化剂存在下通过部分氢化脂族α，ω-二腈制备脂族α，ω-氨基亚硝酸盐的方法，其中用于部分氢化的催化剂包括（a）铁或基于铁或其混合物的化合物 和（b）基于（a）0.01至5重量％的基于2,3,4或5个选自铝，硅，锆，钛和钒的元素的促进剂，和（c） 基于（a）的0至5重量％的基于碱金属或碱土金属的化合物。