公开(公告)号：US11752018B2

公开(公告)日：2023-09-12

申请号：US17583670

申请日：2022-01-25

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Laura Elizabeth Firstenberg ,  Sean P. Fleury

IPC: A61F2/848 ,  A61F2/06 ,  A61F2/07 ,  A61F2/00 ,  A61F2/04

CPC classification number: A61F2/848 ,  A61F2/0077 ,  A61F2/04 ,  A61F2/06 ,  A61F2/064 ,  A61F2/07 ,  A61F2002/0081 ,  A61F2002/044 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2002/8483 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2250/0063 ,  Y10T156/10

Abstract: An endoprosthesis has an expanded state and an unexpanded state, the endoprosthesis includes a stent, wherein the stent has a first end, a second end, an inner surface defining a lumen, an outer surface, and a thickness defined between the inner surface and the outer surface; and a stent end covering disposed at one of the first and second ends, the stent end covering including a polymeric coating that includes a base and a plurality of protrusions, the base including a first major surface facing the outer surface of the stent, the base further including a second major surface from which each of the plurality of protrusions extends outwardly, the first major surface opposing the second major surface, wherein the protrusions are arranged in a micropattern. Methods of making and using an endoprosthesis are provided.

公开(公告)号：US11259943B2

公开(公告)日：2022-03-01

申请号：US16439136

申请日：2019-06-12

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Laura Elizabeth Firstenberg ,  Sean P. Fleury

IPC: A61F2/04 ,  A61F2/848 ,  A61F2/06 ,  A61F2/07 ,  A61F2/00

Abstract: An endoprosthesis has an expanded state and an unexpanded state, the endoprosthesis includes a stent, wherein the stent has a first end, a second end, an inner surface defining a lumen, an outer surface, and a thickness defined between the inner surface and the outer surface; and a stent end covering disposed at one of the first and second ends, the stent end covering including a polymeric coating that includes a base and a plurality of protrusions, the base including a first major surface facing the outer surface of the stent, the base further including a second major surface from which each of the plurality of protrusions extends outwardly, the first major surface opposing the second major surface, wherein the protrusions are arranged in a micropattern. Methods of making and using an endoprosthesis are provided.

公开(公告)号：US10548708B2

公开(公告)日：2020-02-04

申请号：US15355529

申请日：2016-11-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： William Bertolino ,  Laura Elizabeth Firstenberg ,  Claire M. McLeod ,  Andrea Lai ,  Sandra Lam ,  Shannon Taylor

IPC: A61F2/82 ,  A61F2/04 ,  A61F2/848 ,  A61F2/90 ,  B29C65/48 ,  B29C65/00 ,  B29C45/37 ,  B29C53/58 ,  B29D23/00 ,  B29K101/00 ,  B29L23/00 ,  B29L31/00 ,  B29L16/00 ,  B29C41/14 ,  B29C33/42 ,  B29C39/02 ,  B29C39/10 ,  B29C41/20

Abstract: An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen, having an outer surface, and defining a plurality of apertures through the outer surface, wherein the apertures are arranged in a micropattern; and a coating (e.g., polymeric coating) attached to the outer surface of the stent. The coating includes a base and a tissue engagement portion including a second surface facing outwardly from the stent, the tissue engagement portion including a structure that defines a plurality of holes extending inwardly from the second surface toward the base. The holes are arranged in a micropattern. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the structure applies a force that may reduce stent migration by creating an interlock between the vessel wall and the endoprosthesis.

公开(公告)号：US09526640B2

公开(公告)日：2016-12-27

申请号：US14459084

申请日：2014-08-13

Applicant: Boston Scientific Scimed, Inc.

Inventor： William Bertolino ,  Laura Elizabeth Firstenberg ,  Claire M McLeod ,  Andrea Lai ,  Sandra Lam ,  Shannon Taylor

IPC: A61F2/848 ,  A61F2/90 ,  A61F2/04 ,  B29C65/48 ,  B29C53/58 ,  B29D23/00 ,  B29K101/00 ,  B29L23/00 ,  B29L31/00 ,  B29L16/00 ,  B29C65/00 ,  B29C41/14 ,  B29C33/42 ,  B29C39/02 ,  B29C39/10 ,  B29C41/20

CPC classification number: A61F2/04 ,  A61F2/07 ,  A61F2/848 ,  A61F2/90 ,  A61F2002/044 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2240/001 ,  A61F2250/0059 ,  B29C33/42 ,  B29C33/424 ,  B29C39/026 ,  B29C39/10 ,  B29C41/14 ,  B29C41/20 ,  B29C45/372 ,  B29C53/587 ,  B29C65/48 ,  B29C66/1122 ,  B29C66/52272 ,  B29C66/5326 ,  B29C66/742 ,  B29D23/00 ,  B29D23/001 ,  B29K2101/00 ,  B29L2016/00 ,  B29L2023/00 ,  B29L2031/7532 ,  B29L2031/7534

Abstract: An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen, having an outer surface, and defining a plurality of apertures through the outer surface, wherein the apertures are arranged in a micropattern; and a coating (e.g., polymeric coating) attached to the outer surface of the stent. The coating includes a base and a tissue engagement portion including a second surface facing outwardly from the stent, the tissue engagement portion including a structure that defines a plurality of holes extending inwardly from the second surface toward the base. The holes are arranged in a micropattern. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the structure applies a force that may reduce stent migration by creating an interlock between the vessel wall and the endoprosthesis.

Abstract translation: 内假体具有扩张状态和收缩状态，内假体包括具有限定内腔的内表面的支架，具有外表面，并且通过外表面限定多个孔，其中所述孔布置在微图案中; 以及附着到支架的外表面的涂层（例如，聚合物涂层）。 涂层包括基部和组织接合部分，其包括从支架向外的第二表面，所述组织接合部分包括限定从第二表面朝向基部向内延伸的多个孔的结构。 孔布置在微图案中。 当在由血管壁限定的内腔中将内假体扩张到扩张状态时，该结构施加可以通过在血管壁和内用假体之间产生互锁来减少支架迁移的力。

公开(公告)号：US20130268063A1

公开(公告)日：2013-10-10

申请号：US13857998

申请日：2013-04-06

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Laura Elizabeth Firstenberg ,  Claire M. McLeod ,  Shannon Taylor ,  Andrea Lai ,  Sandra Lam

IPC: A61F2/06

CPC classification number: A61F2/06 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/044 ,  A61F2230/0078 ,  A61F2250/0026 ,  A61F2250/0039

Abstract: An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen and an outer surface; and a polymeric coating adhered to the outer surface of the stent. The polymeric coating includes a base and a plurality of protrusions extending outwardly from the base. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the protrusions apply a force that creates an interlock between the vessel wall and the endoprosthesis.

Abstract translation: 内假体具有扩张状态和收缩状态，内假体包括具有限定内腔和外表面的内表面的支架; 以及粘附到支架外表面的聚合物涂层。 聚合物涂层包括基部和从基部向外延伸的多个突起。 当内置假体在由血管壁限定的内腔中扩张至扩张状态时，突出部施加一个力，该力在血管壁和内假体之间产生互锁。