公开(公告)号：US08471229B2

公开(公告)日：2013-06-25

申请号：US13237851

申请日：2011-09-20

Applicant: Abigail Freeman ,  Gregory S. Simmons ,  Brian D. Riggs ,  Robert Harrison ,  Dan Castro ,  Bin Huang

Inventor： Abigail Freeman ,  Gregory S. Simmons ,  Brian D. Riggs ,  Robert Harrison ,  Dan Castro ,  Bin Huang

IPC: G02B5/00 ,  G21K1/00 ,  H01J1/52 ,  H01J3/00 ,  H01J5/18 ,  H01J29/46 ,  G01N21/00 ,  G21F5/00 ,  G21F1/00 ,  G21F3/00 ,  G21F7/00 ,  G21C11/00 ,  A61L2/00

CPC classification number: A61L2/08 ,  A61L2/081 ,  A61L2/087 ,  A61L2202/24

Abstract: Methods and systems for selection radiation exposure in sterilization of medical devices are disclosed.

公开(公告)号：US08470014B2

公开(公告)日：2013-06-25

申请号：US11893316

申请日：2007-08-14

Applicant: David C. Gale ,  Klaus Kleine ,  Anthony Abbate ,  Svava M. Atladottir ,  Bin Huang

Inventor： David C. Gale ,  Klaus Kleine ,  Anthony Abbate ,  Svava M. Atladottir ,  Bin Huang

IPC: A61F2/06

CPC classification number: A61F2/958 ,  A61F2002/30062 ,  A61F2002/30448 ,  A61F2002/9522 ,  A61F2002/9583 ,  A61F2210/0004 ,  A61F2220/005

Abstract: Medical assemblies with a releasable connection and methods of constructing such medical assemblies are disclosed. The medical assemblies generally comprise a stent, a catheter assembly having catheter body a balloon, and a releasable connection between the stent and the catheter assembly that releases the stent from the catheter assembly in response to enlargement of the balloon or when the balloon has been enlarged to an expanded configuration.

Abstract translation: 公开了具有可释放连接的医疗组件和构造这种医疗组件的方法。 医疗组件通常包括支架，具有导管主体的气囊的导管组件，以及支架和导管组件之间的可释放连接，其响应于气囊的扩大或者当球囊已经扩大时从导管组件释放支架 扩展配置。

公开(公告)号：US20120319333A1

公开(公告)日：2012-12-20

申请号：US13597161

申请日：2012-08-28

Applicant: Bin Huang ,  David C. Gale ,  Vincent J. Gueriguian

Inventor： Bin Huang ,  David C. Gale ,  Vincent J. Gueriguian

IPC: B29C49/64

CPC classification number: A61F2/91 ,  A61F2/90 ,  B29C49/0005 ,  B29C49/6472 ,  B29C2049/0089 ,  B29K2105/258 ,  B29K2995/006 ,  B29L2031/7542

Abstract: Methods to expand polymer tubing with desirable or optimum morphology and mechanical properties for stent manufacture and fabrication of a stent therefrom are disclosed.

Abstract translation: 公开了扩展聚合物管的方法，其具有用于支架制造和制造支架的所需或最佳形态和机械性能。

公开(公告)号：US08267990B2

公开(公告)日：2012-09-18

申请号：US12872166

申请日：2010-08-31

Applicant: David C. Gale ,  Bin Huang ,  Vincent Gueriguian ,  Syed Faiyaz Ahmed Hossainy

Inventor： David C. Gale ,  Bin Huang ,  Vincent Gueriguian ,  Syed Faiyaz Ahmed Hossainy

IPC: A61F2/82

CPC classification number: A61L31/148 ,  A61L31/06 ,  C08L67/04

Abstract: Stents fabricated from hydrolytically degradable polymers with accelerated degradation rates and methods of fabricating stents with accelerated degradation rates are disclosed.

Abstract translation: 公开了由具有加速降解速率的水解可降解聚合物制备的支架和具有加速降解速率的制造支架的方法。

公开(公告)号：US08057531B2

公开(公告)日：2011-11-15

申请号：US11823954

申请日：2007-06-29

Applicant: Bin Huang ,  David C. Gale

Inventor： Bin Huang ,  David C. Gale

IPC: A61F2/06

CPC classification number: A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/9155 ,  A61F2210/0057 ,  A61F2250/001 ,  A61F2250/0029 ,  A61F2250/0036 ,  A61F2250/0071 ,  A61L31/06 ,  A61L31/14 ,  C08L67/04

Abstract: A method of treating a bodily lumen with a stent including disposing a stent within a bodily lumen in which the stent has a plurality of deformable struts that are substantially circumferentially aligned is described. The deformable struts are configured to selectively deform in a circumferential direction in localized regions in the struts upon application of an outward radial force. The stent is expanded by applying the outward radial force which causes selective deformation of the deformable struts in a localized region in the struts.

Abstract translation: 描述了一种用支架处理体腔的方法，包括将支架置于体腔中，其中支架具有基本上周向对准的多个可变形支柱。 可变形支柱构造成在施加向外的径向力时在支柱中的局部区域中沿圆周方向选择性地变形。 通过施加向外的径向力来扩张支架，所述向外的径向力导致支柱中的局部区域中的可变形支柱的选择性变形。

公开(公告)号：US08034287B2

公开(公告)日：2011-10-11

申请号：US11803829

申请日：2007-05-15

Applicant: Abigail Freeman ,  Gregory S. Simmons ,  Brian D. Riggs ,  Robert Harrison ,  Dan Castro ,  Bin Huang

Inventor： Abigail Freeman ,  Gregory S. Simmons ,  Brian D. Riggs ,  Robert Harrison ,  Dan Castro ,  Bin Huang

IPC: A61L2/00 ,  G03C5/04 ,  G03C1/815 ,  G03C1/825

CPC classification number: A61L2/08 ,  A61L2/081 ,  A61L2/087 ,  A61L2202/24

Abstract: Methods and systems for selection radiation exposure in sterilization of medical devices are disclosed.

Abstract translation: 公开了用于在医疗装置灭菌中选择辐射照射的方法和系统。

公开(公告)号：US07971333B2

公开(公告)日：2011-07-05

申请号：US11443947

申请日：2006-05-30

Applicant: David C. Gale ,  Bin Huang ,  Anthony J. Abbate ,  Timothy A. Limon ,  Klaus Kleine

Inventor： David C. Gale ,  Bin Huang ,  Anthony J. Abbate ,  Timothy A. Limon ,  Klaus Kleine

IPC: B21D39/00 ,  B23P11/02

CPC classification number: A61F2/915 ,  A61F2/82 ,  A61F2/91 ,  A61F2002/821 ,  A61F2210/0004 ,  A61F2210/0076 ,  B23K26/384 ,  B23K26/402 ,  B23K2103/42 ,  B23K2103/50 ,  B29C47/0004 ,  B29C47/0023 ,  B29C47/0066 ,  B29C55/00 ,  B29C55/24 ,  B29C65/02 ,  B29C66/534 ,  B29C71/0063 ,  B29C2793/0009 ,  B29K2995/0039 ,  B29K2995/006 ,  B29L2031/7534 ,  Y10T29/49874 ,  Y10T29/49908 ,  Y10T29/49913 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/49995

Abstract: Methods and systems of fabricating a polymeric stent are disclosed herein. Methods are disclosed that include forming a polymeric tube using extrusion, radially deforming the formed tube so that the deformed tube comprises a target diameter, forming a stent from the deformed tube, and forming a stent from the deformed tube. The stent is formed by laser machining a stent pattern in the deformed tube with an ultra-short pulse laser. Disclosed methods further include crimping the stent on a support element, wherein a temperature of the stent during crimping is above an ambient temperature.

Abstract translation: 本文公开了制造聚合物支架的方法和系统。 公开的方法包括使用挤出形成聚合物管，使成形的管径向变形，使得变形的管包括靶直径，从变形的管形成支架，以及从变形的管形成支架。 通过用超短脉冲激光在变形管中激光加工支架图案来形成支架。 公开的方法还包括将支架卷曲在支撑元件上，其中在卷曲期间支架的温度高于环境温度。

公开(公告)号：US07943066B2

公开(公告)日：2011-05-17

申请号：US11905856

申请日：2007-10-04

Applicant: Yonghao Ni ,  Bin Huang ,  Guojun Kang

Inventor： Yonghao Ni ,  Bin Huang ,  Guojun Kang

IPC: H01B1/20 ,  D21F11/00

CPC classification number: H01B1/20 ,  H01B1/127 ,  H01B1/128

Abstract: The present invention provides electrically conductive paper composites prepared from cellulose fibers modified to bind a conducting polymer to a surface of the cellulose fibers and mixing these with unmodified cellulose fibers and forming paper products from the composite. Conducting paper composites so formed were investigated for their conductivity and strength properties as a function of monomer dosage or percentage of modified fibers in the mixture and for the composites it was found that less monomer (i.e. conductive polymer) was needed to achieve the same conductivity obtained from conducting paper made from only the modified cellulose. A higher tensile strength was obtained with the composite conducting paper than was attained with conducting paper made from only the modified cellulose. The electrically conductive paper composites may also be prepared from cellulose fibers mixed with particulate fillers modified to bind a conducting polymer to a surface of the particulate fillers.

Abstract translation: 本发明提供由纤维素纤维制备的导电纸复合材料，其被修饰以将导电聚合物结合到纤维素纤维的表面，并将它们与未改性的纤维素纤维混合并从复合材料中形成纸产品。 研究了如此形成的导电纸复合材料的导电性和强度性能，作为混合物中单体剂量或改性纤维百分比的函数，并且对于复合材料，发现需要较少的单体（即导电聚合物）以获得相同的导电性 从仅由改性纤维素制成的纸。 使用复合导电纸获得的拉伸强度比用仅由改性纤维素制成的导电纸获得的拉伸强度更高。 导电纸复合材料也可以由与被改性以将导电聚合物结合到颗粒填料的表面的颗粒填料混合的纤维素纤维制备。

公开(公告)号：US07901452B2

公开(公告)日：2011-03-08

申请号：US11823702

申请日：2007-06-27

Applicant: David C. Gale ,  Bin Huang ,  Yunbing Wang

Inventor： David C. Gale ,  Bin Huang ,  Yunbing Wang

IPC: A61F2/06 ,  A61L33/00 ,  B27N3/08 ,  B29C33/40

CPC classification number: A61F2/91 ,  A61F2002/0086 ,  A61F2210/0076 ,  A61F2250/0025 ,  B23K2103/42 ,  B23K2103/50 ,  B29C55/24 ,  B29C2793/0009 ,  B29D23/001 ,  B29L2009/005 ,  B29L2023/007 ,  B29L2031/7534 ,  Y10T83/0419

Abstract: Methods of fabricating a stent and a stent having selected morphology on abluminal and luminal surfaces of the stent are disclosed.

Abstract translation: 公开了制造支架和在支架的腔内和腔表面上具有选择的形态的支架的方法。

公开(公告)号：US20110052712A1

公开(公告)日：2011-03-03

申请号：US12705436

申请日：2010-02-12

Applicant: Donald J. Eaton ,  Bin Huang ,  Michael A. Savitt

Inventor： Donald J. Eaton ,  Bin Huang ,  Michael A. Savitt

IPC: A61K31/765 ,  A61K9/14 ,  A61P41/00

CPC classification number: A61K9/0014 ,  A61K9/12 ,  A61K31/765 ,  A61K47/32 ,  A61K47/36 ,  A61L26/0076 ,  C08L5/08 ,  C08L23/0869 ,  C08L29/04 ,  C08L2201/06

Abstract: A formulation for generating an adhesion barrier that includes a plurality of particles or a dry powder that is made of a polymer combination of at least one biodegradable polymer and at least one water soluble polymer is disclosed. Methods of making and delivering the formulation are further disclosed. The formulation of particles is deposited on a surface of internal body tissue and the deposited formulation absorbs moisture from the tissue and forms a film over the surface. The film acts as an adhesion barrier by reducing or preventing adhesion of the surface to other body tissue.

Abstract translation: 公开了一种用于产生粘合屏障的制剂，其包括多个颗粒或由至少一种生物可降解聚合物和至少一种水溶性聚合物的聚合物组合制成的干粉。 制备和递送制剂的方法进一步公开。 颗粒的配方沉积在内部身体组织的表面上，并且沉积的制剂从组织中吸收水分并在表面上形成膜。 通过减少或防止表面粘附到其他身体组织上，膜用作粘合屏障。