公开(公告)号：US20150335539A1

公开(公告)日：2015-11-26

申请号：US14654512

申请日：2012-12-24

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Michael Prencipe ,  Xiao Yi Huang ,  Yuan Hui Xie

IPC: A61K8/19 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/21

CPC classification number: A61K8/24 ,  A61K8/19 ,  A61K8/21 ,  A61K8/27 ,  A61K8/365 ,  A61K2800/30 ,  A61Q11/00

Abstract: The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.

Abstract translation: 本发明涉及具有高水含量的口腔护理组合物，其具有改善的对微生物攻击的鲁棒性。 口腔护理组合物包括包含0.125重量％至0.75重量％的水溶性亚锡离子源的组合物，其中所述组合物包含至少50重量％的水，并且其中所述亚锡离子源选自氯化亚锡 ，焦磷酸亚锡，甲酸亚锡，乙酸亚锡，葡萄糖酸亚锡，乳酸亚锡，酒石酸亚锡，草酸亚锡，丙二酸亚锡，柠檬酸亚锡，亚乙基亚乙基氧化物及其混合物。

公开(公告)号：US20150328094A1

公开(公告)日：2015-11-19

申请号：US14654511

申请日：2012-12-24

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Yun Xu ,  Xiao Yi Huang ,  Yuan Hui Xie ,  Xiong Fei Qin

IPC: A61K8/25 ,  A61K8/365 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/19

CPC classification number: A61K8/19 ,  A61K8/25 ,  A61K8/27 ,  A61K8/365 ,  A61K2800/28 ,  A61K2800/592 ,  A61Q11/00

Abstract: The present invention relates to a tooth whitening oral care composition, the use of abrasives in such an oral care composition, a method of polishing tooth enamel, and an oral care kit comprising the oral care composition.

Abstract translation: 本发明涉及牙齿美白口腔护理组合物，在这种口腔护理组合物中使用研磨剂，抛光牙釉质的方法和包含口腔护理组合物的口腔护理套件。

公开(公告)号：US11253446B2

公开(公告)日：2022-02-22

申请号：US16719693

申请日：2019-12-18

Applicant: Colgate-Palmolive Company

Inventor： Yun Xu ,  Xiao Yi Huang ,  Yuan Hui Xie ,  Xiong Fei Qin

IPC: A61K8/24 ,  A61K8/365 ,  A61K8/73 ,  A61K8/27 ,  A61Q11/00

Abstract: Disclosed herein are oral care compositions comprising: a) one or more pyrophosphate compounds, wherein the total concentration of pyrophosphate compounds in the composition is 0.5 wt % to 1.5 wt %, based on the weight of the oral care composition; b) one or more thickening gums, wherein the total concentration of thickening gums in the composition is 1.25 wt % to 1.6 wt %, based on the weight of the oral care composition; and c) a metal ion source.

公开(公告)号：US10576032B2

公开(公告)日：2020-03-03

申请号：US15104780

申请日：2014-12-10

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Yun Xu ,  Xiao Yi Huang

IPC: A61K8/44 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/365

Abstract: An oral care composition comprising serine and one or more zinc salts for use in reducing or inhibiting biofilm formation in an oral cavity.

公开(公告)号：US10342750B2

公开(公告)日：2019-07-09

申请号：US15106280

申请日：2014-12-19

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Yun Xu ,  Xiao Yi Huang ,  Steven Fisher ,  Betty Won ,  Lyndsay Schaeffer-Korbylo

IPC: A61K8/27 ,  A61K31/32 ,  A61K8/24 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a combination of zinc oxide and zinc citrate, and methods of preparing and using the same.

公开(公告)号：US10195124B2

公开(公告)日：2019-02-05

申请号：US14654512

申请日：2012-12-24

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Xiao Yi Huang ,  Yuan Hui Xie

IPC: A61K8/27 ,  A61Q11/00 ,  A61K31/32 ,  A61K8/24 ,  A61K8/19 ,  A61K8/365 ,  A61K8/21

Abstract: The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.

公开(公告)号：US10064794B2

公开(公告)日：2018-09-04

申请号：US14654511

申请日：2012-12-24

Applicant: Colgate-Palmolive Company

Inventor： Yun Xu ,  Xiao Yi Huang ,  Yuan Hui Xie ,  Xiong Fei Qin

IPC: A61Q11/00 ,  A61K8/19 ,  A61K8/27 ,  A61K8/25 ,  A61K33/06 ,  A61K8/365

Abstract: The present invention relates to a tooth whitening oral care composition, the use of abrasives in such an oral care composition, a method of polishing tooth enamel, and an oral care kit comprising the oral care composition.