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公开(公告)号：US20100112714A1
公开(公告)日：2010-05-06
申请号：US12684611
申请日：2010-01-08
Applicant: Chung-Cheng Chang , Jau-Der Chen , Pei-Tai Chen
Inventor： Chung-Cheng Chang , Jau-Der Chen , Pei-Tai Chen
CPC classification number: B01L3/5027 , B01L3/5023 , B01L7/00 , B01L2200/0642 , B01L2300/069 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/0877 , B01L2300/0887 , B01L2400/086 , Y10T436/143333
Abstract: The present invention relates to a biochip for nucleic acid hybridization. The biochip of the present invention comprises a hybridization chamber which is in the form of a cavity, a porous membrane pressed in the hybridization chamber; and at least one first circulation hole and at least one second circulation hole which are communicated with the hybridization chamber so that the reaction solution flows in the at least one first circulation hole and flows out the at least one second circulation hole through the pores of the porous membrane. The hybridization reaction area is increased by flowing the reaction solution through the pores of the membrane, which enable the reaction sensitivity to be increased. The diffusion distance for the reaction molecules is decreased due to the limited inside space of the membrane, and thereby the hybridization time is shortened.
Abstract translation: 本发明涉及用于核酸杂交的生物芯片。 本发明的生物芯片包括空腔形式的杂交室，在杂交室中压制的多孔膜; 以及与所述杂交室连通的至少一个第一循环孔和至少一个第二循环孔，使得所述反应溶液在所述至少一个第一循环孔中流动，并且流出所述至少一个第二循环孔，穿过所述孔的孔 多孔膜。 通过使反应溶液流过膜的孔隙来增加杂交反应面积，使反应灵敏度提高。 由于膜的内部空间有限，反应分子的扩散距离减小，从而缩短了杂交时间。
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公开(公告)号：US20080199946A1
公开(公告)日：2008-08-21
申请号：US11675637
申请日：2007-02-16
Applicant: Chung-Cheng Chang , Jau-Der Chen , Pei-Tai Chen
Inventor： Chung-Cheng Chang , Jau-Der Chen , Pei-Tai Chen
IPC: C12M1/34
CPC classification number: B01L3/502715 , B01L3/5023 , B01L3/502746 , B01L2200/0642 , B01L2300/069 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/0877 , B01L2300/0887 , B01L2400/086
Abstract: The present invention relates to a biochip for nucleic acid hybridization. The biochip of the present invention comprises a hybridization chamber which is in the form of a cavity, a porous matrix pressed in the hybridization chamber; and at least one first circulation hole and at least one second circulation hole which are communicated with the hybridization chamber so that the reaction solution flows in the at least one first circulation hole and flows out the at least one second circulation hole through the pores of the porous matrix. The hybridization reaction area is increased by flowing the reaction solution through the pores of the membrane, which enable the reaction sensitivity to be increased. The diffusion distance for the reaction molecules is decreased due to the limited inside space of the membrane, and thereby the hybridization time is shortened.
Abstract translation: 本发明涉及用于核酸杂交的生物芯片。 本发明的生物芯片包括空腔形式的杂交室，在杂交室中压制的多孔基质; 以及与所述杂交室连通的至少一个第一循环孔和至少一个第二循环孔，使得所述反应溶液在所述至少一个第一循环孔中流动，并且流出所述至少一个第二循环孔，穿过所述孔的孔 多孔基体。 通过使反应溶液流过膜的孔隙来增加杂交反应面积，使反应灵敏度提高。 由于膜的内部空间有限，反应分子的扩散距离减小，从而缩短了杂交时间。
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公开(公告)号：US20080111535A1
公开(公告)日：2008-05-15
申请号：US11772421
申请日：2007-07-02
Applicant: Jen-Ta SU , Hsin-Liang Lin , Chung-Cheng Chang , Pei-Sheng Liao
Inventor： Jen-Ta SU , Hsin-Liang Lin , Chung-Cheng Chang , Pei-Sheng Liao
CPC classification number: H02M3/00 , H02M7/003 , H05K1/141 , H05K7/209 , H05K2201/10545
Abstract: The present invention provides a separate type converter. The separate type converter includes a power control module having a power control circuit generating a first control signal, and a power stage module having a power stage circuit coupled to the power control circuit for receiving the first control signal and an input voltage, and generating an output voltage, in which the power control module and the power stage module are separate from each other in an assembling structure.
Abstract translation: 本发明提供一种单独的类型转换器。 分离式转换器包括具有产生第一控制信号的功率控制电路的功率控制模块和功率级模块，功率级模块具有耦合到功率控制电路的功率级电路，用于接收第一控制信号和输入电压， 输出电压，其中功率控制模块和功率级模块在组装结构中彼此分离。
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