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11.发明申请公开(公告)号：US20140055496A1
公开(公告)日：2014-02-27
申请号：US13594788
申请日：2012-08-25
Applicant: David Cunningham , Benjamin W. Herta , Vijay A. Saraswat , Avraham E. Shinnar
Inventor： David Cunningham , Benjamin W. Herta , Vijay A. Saraswat , Avraham E. Shinnar
IPC: G09G5/00
CPC classification number: G09G5/00 , G06F17/30 , G06F17/30545
Abstract: Executing a map reduce sequence may comprise executing all jobs in the sequence by a collection of a plurality of processes with each process running one or more mappers, combiners, partitioners and reducers for each job, and transparently sharing heap state between the jobs to improve metrics associated with the job. Processes may communicate among themselves to coordinate completion of map, shuffle and reduce phases, and completion of said all jobs in the sequence.
Abstract translation: 执行地图缩减序列可以包括通过多个进程的集合执行序列中的所有作业，每个进程为每个作业运行一个或多个映射器，组合器，分区器和缩减器，并且在作业之间透明地共享堆状态以改善度量 与工作有关。 过程可以在它们之间进行通信，以协调地图的完成，洗牌和减少阶段，以及完成所述序列中的所有作业。
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12.发明申请Incandescent lamp incorporating extended high-reflectivity IR coating and lighting fixture incorporating such an incandescent lamp 审中-公开白炽灯采用延长的高反射率红外线涂层和装有这种白炽灯的灯具公开(公告)号：US20060226777A1
公开(公告)日：2006-10-12
申请号：US11388770
申请日：2006-03-24
Applicant: David Cunningham
Inventor： David Cunningham
IPC: H01K1/00
CPC classification number: H01K1/325 , C03C17/005 , C03C17/3417 , F21V7/22 , G02B5/282 , H01K3/005
Abstract: An incandescent lamp is disclosed, incorporating a special optical coating system that enables the lamp to provide an improved luminous efficacy. In one form, the optical coating system includes a plurality of dielectric layers having prescribed refractive indices and prescribed thicknesses, which are selected such that the optical coating provides a prescribed transmittance/reflectance spectrum having an average reflectance greater than 90% across an infrared wavelength range of 740 to 2000 nm and further having an average transmittance of less than 90% across a visible wavelength range of 400 to 700 nm. In another form, the optical coating system includes two distinct coatings: (1) a first coating including a plurality of dielectric layers having prescribed refractive indices and prescribed thicknesses, which are selected such that the first coating provides a prescribed transmittance/reflectance spectrum, and (2) a second coating including a transparent electrically conductive material configured such that the second coating provides a prescribed transmittance/reflectance spectrum. The invention also is embodied in a lighting fixture incorporating an optical coating as described above, located either on the envelope of the incandescent lamp, itself, or on another substrate of the fixture, separate and apart from the lamp, e.g., a fixed transparent envelope surrounding the incandescent lamp.
Abstract translation: 公开了一种白炽灯，其包括使灯能够提供改善的发光效率的特殊光学涂层系统。 在一种形式中，光学涂层系统包括具有规定折射率和规定厚度的多个介电层，其被选择为使得光学涂层提供在红外波长范围内具有大于90％的平均反射率的规定的透射率/反射光谱 为740〜2000nm，在400〜700nm的可见光波长范围内的平均透射率为90％以下。 在另一种形式中，光学涂层系统包括两个不同的涂层：（1）包括具有规定折射率和规定厚度的多个电介质层的第一涂层，其被选择为使得第一涂层提供规定的透射率/反射光谱，以及 （2）包括透明导电材料的第二涂层，其被配置为使得第二涂层提供规定的透射率/反射光谱。 本发明还体现在包括如上所述的光学涂层的照明器具中，该光学涂层位于白炽灯本身的封套上，或位于固定装置的另一基板上，与灯分离和分开，例如固定的透明封套 围绕白炽灯。
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13.发明授权
公开(公告)号：US5624817A
公开(公告)日：1997-04-29
申请号：US234265
申请日：1994-04-28
Applicant: Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch , Matthew R. Pincus
Inventor： Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch , Matthew R. Pincus
CPC classification number: A61K47/48238 , C07K14/705 , A61K38/00
Abstract: The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide more reactive with yon Willebrand factor. Preferably, the mutation is in the hinge region of GP Ib.alpha., such as the substitution of valine for glycine at residue 233. These mutations alter the three-dimensional structure of the mutant polypeptide from a beta bend conformation to an alpha helix formation, and also create an amphipathic region within the mutant polypeptide. DNA encoding the mutant polypeptides, as well as expression systems for the production of the mutant polypeptides, are also provided. Methods and compositions using the mutant polypeptides and DNA oligomers complementary to the mutant polypeptides are further provided.
Abstract translation: 本发明提供由天然存在的野生型血小板糖蛋白Ibα编码的纯化多肽，其具有使得多肽与阴离子血友病因子更具反应性的突变。 优选地，突变位于GPIbα的铰链区，例如在残基233处取代缬氨酸甘氨酸。这些突变将突变多肽的三维结构从β弯曲构象改变为α螺旋形成，并且 还在突变体多肽内产生两亲性区域。 还提供了编码突变体多肽的DNA，以及用于产生突变体多肽的表达系统。 还提供了使用与突变体多肽互补的突变多肽和DNA寡聚体的方法和组合物。
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14.发明授权
公开(公告)号：US5317097A
公开(公告)日：1994-05-31
申请号：US770968
申请日：1991-10-07
Applicant: Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch
Inventor： Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch
CPC classification number: A61K47/48238 , C07K14/705 , A61K38/00
Abstract: The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide more reactive with von Willebrand factor. Preferably, the mutation is in the hinge region of GP Ib.alpha., such as the substitution of valine for glycine at residue 233. These mutations alter the three-dimensional structure of the mutant polypeptide from a beta bend conformation to an alpha helix formation, and also create an amphipathic region within the mutant polypeptide. DNA encoding the mutant polypeptides, as well as expression systems for the production of the mutant polypeptides, are also provided. Methods and compositions using the mutant polypeptides and DNA oligomers complementary to the mutant polypeptides are further provided.
Abstract translation: 本发明提供由天然存在的野生型血小板糖蛋白Ibα编码的纯化多肽，其具有使得多肽与血管性血友病因子更具反应性的突变。 优选地，突变位于GPIbα的铰链区，例如在残基233处取代缬氨酸甘氨酸。这些突变将突变多肽的三维结构从β弯曲构象改变为α螺旋形成，并且 还在突变体多肽内产生两亲性区域。 还提供了编码突变体多肽的DNA，以及用于产生突变体多肽的表达系统。 还提供了使用与突变体多肽互补的突变多肽和DNA寡聚体的方法和组合物。
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Patent Agency Ranking
15.发明授权公开(公告)号：US09147373B2
公开(公告)日：2015-09-29
申请号：US13594788
申请日：2012-08-25
Applicant: David Cunningham , Benjamin W. Herta , Vijay A. Saraswat , Avraham E. Shinnar
Inventor： David Cunningham , Benjamin W. Herta , Vijay A. Saraswat , Avraham E. Shinnar
CPC classification number: G09G5/00 , G06F17/30 , G06F17/30545
Abstract: Executing a map reduce sequence may comprise executing all jobs in the sequence by a collection of a plurality of processes with each process running one or more mappers, combiners, partitioners and reducers for each job, and transparently sharing heap state between the jobs to improve metrics associated with the job. Processes may communicate among themselves to coordinate completion of map, shuffle and reduce phases, and completion of said all jobs in the sequence.
Abstract translation: 执行地图缩减序列可以包括通过多个进程的集合执行序列中的所有作业，每个进程为每个作业运行一个或多个映射器，组合器，分区器和缩减器，并且在作业之间透明地共享堆状态以改善度量 与工作有关。 过程可以在它们之间进行通信，以协调地图的完成，洗牌和减少阶段，以及完成所述序列中的所有作业。
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公开(公告)号：US20070010151A1
公开(公告)日：2007-01-11
申请号：US10558825
申请日：2004-05-27
Applicant: David Cunningham
Inventor： David Cunningham
CPC classification number: B32B27/12 , F41H5/0478 , Y10S428/911 , Y10T428/24058 , Y10T428/24174 , Y10T428/24942 , Y10T442/2615 , Y10T442/2623 , Y10T442/3854 , Y10T442/3886
Abstract: A ballistic composite comprises multiple layers of a fabric having unidirectional ballistic resistant yarns in at least two layers and a resin layer between each pair of such multiple layers adhered to the ballistic resistant yarns but not encapsulation the same and not penetrating the layer of fabric. The ballistic yarn layers are at 90°±5° with respect to each other and the ballistic resistant yarns are stabilized by being woven in a second fabric. The second fabric is formed of yarns having a substantially lower tenacity and tensile modulus than the ballistic resistant yarn. The ballistic resistant yarns have a tenacity of at least about 15 grams per denier and a modulus of at least about 40 grams per denier. The resin in the resin layer has a modulus of at least about 7000 psi.
Abstract translation: 弹道复合材料包括多层织物，其具有至少两层中的单向防弹纱线，并且每对这样的多层之间的树脂层粘附在防弹纱线上，但不包封并且不穿透织物层。 弹道纱层相对于彼此为90°±5°，防弹纱线通过在第二织物中编织而稳定。 第二织物由具有比防弹纱线显着更低的强度和拉伸模量的纱线形成。 防弹纱具有至少约15克/旦尼尔的强度和至少约40克/旦尼尔的模量。 树脂层中的树脂的模量为至少约7000psi。
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17.发明申请公开(公告)号：US20050225757A1
公开(公告)日：2005-10-13
申请号：US11146479
申请日：2005-06-06
Applicant: David Cunningham
Inventor： David Cunningham
CPC classification number: H05B33/0869 , H05B33/0872
Abstract: A method is disclosed for controlling a lighting fixture of a kind having individually colored light sources, e.g., LEDs, that emit light having a distinct luminous flux spectrum that varies in its initial spectral composition, that varies with temperature, and that degrades over time. The method controls such fixture so that it projects light having a predetermined desired flux spectrum despite variations in initial spectral characteristics, despite variations in temperature, and despite flux degradations over time.
Abstract translation: 公开了一种用于控制具有单独着色的光源（例如LED）的照明器具的方法，其发射具有随着温度变化的其初始光谱组成变化的具有不同光通量光谱的光的光，并随着时间而劣化。 该方法控制这种固定装置，尽管尽管温度变化，尽管随着时间的流逝退化，但是尽管有初始光谱特性的变化，但它投射了具有预定的所需通量光谱的光。
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公开(公告)号：US5492809A
公开(公告)日：1996-02-20
申请号：US119262
申请日：1993-09-09
Applicant: Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch
Inventor： Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch
CPC classification number: C07K14/705 , A61K47/48238 , A61K38/00
Abstract: The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide less reactive with von Willebrand factor. Preferably, the mutation is in the leucine rich region of GPIb.alpha., such as the substitution of phenylalanine for leucine at residue 57. DNA encoding the mutant polypeptides, as well as expression systems for the production of the mutant polypeptides, are also provided. Methods and compositions using the mutant polypeptides and DNA oligomers complementary to the mutant polypeptides are further provided.
Abstract translation: 本发明提供由天然存在的野生型血小板糖蛋白Ibα编码的纯化多肽，其具有使得多肽与血管性血友病因子反应性较低的突变。 优选地，突变位于GPIbα的富含亮氨酸的区域中，例如在残基57处用苯丙氨酸取代亮氨酸。还提供了编码突变多肽的DNA，以及用于产生突变多肽的表达系统。 还提供了使用与突变体多肽互补的突变多肽和DNA寡聚体的方法和组合物。
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公开(公告)号：US5298239A
公开(公告)日：1994-03-29
申请号：US821717
申请日：1992-01-15
Applicant: Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch
Inventor： Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch
IPC: A61K38/00 , A61K47/48 , C07K14/705 , C12N15/12 , A61K37/02 , A61K37/547
CPC classification number: C07K14/705 , A61K47/48238 , A61K38/00
Abstract: The subject invention provides purified polypeptide encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide less reactive with von Willebrand factor. Preferably, the mutation is in the leucine rich region of GPIb.alpha., such as the substitution of phenylalanine for leucine at residue 57. DNA encoding the mutant polypeptides, as well as expression systems for the production of the mutant polypeptides, are also provided. Methods and compositions using the mutant polypeptides and DNA oligomers complementary to the mutant polypeptides are further provided.
Abstract translation: 本发明提供由天然存在的野生型血小板糖蛋白Ibα编码的纯化多肽，其具有使得多肽与血管性血友病因子反应性较低的突变。 优选地，突变位于GPIb（α）的富含亮氨酸的区域中，例如在残基57处取代苯丙氨酸用于亮氨酸。还提供了编码突变体多肽的DNA，以及用于产生突变多肽的表达系统 。 还提供了使用与突变体多肽互补的突变多肽和DNA寡聚体的方法和组合物。
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