-
公开(公告)号：US12110535B2
公开(公告)日：2024-10-08
申请号：US18385300
申请日：2023-10-30
Applicant: Gen-Probe Incorporated
Inventor： David A. Buse , Norbert D. Hagen , David Opalsky
IPC: C12Q1/6806 , B01L3/00 , B01L7/00 , C12Q1/686 , G01N35/04
CPC classification number: C12Q1/6806 , B01L3/50825 , B01L3/565 , B01L7/5255 , C12Q1/686 , G01N35/04 , B01L3/527 , B01L2200/026 , B01L2200/0689 , B01L2300/046 , G01N2035/0418 , G01N2035/0436
Abstract: A method for reconstituting a reagent within a reagent pack including one or more wells and at least one of the wells containing a lyophilized reagent comprises the steps of receiving reagent packs into a reagent pack input carousel, transferring one reagent pack with a rotary distributor from the input carousel to a reagent pack storage carousel, retrieving the reagent pack from the storage carousel with the rotary distributor and placing the reagent pack into a reagent pack loading station, and dispensing a reconstitution reagent with an automated pipettor into the well containing the lyophilized reagent to form a reconstituted reagent.
-
12.发明公开公开(公告)号：US20240150822A1
公开(公告)日：2024-05-09
申请号：US18386976
申请日：2023-11-03
Applicant: Gen-Probe Incorporated
Inventor： David BUSE , David Howard Combs , Norbert D. Hagen , David Opalsky , Bruce Richardson , Anita Frasad , Keith Moravick , Tyler Moore
CPC classification number: C12Q1/686 , B01L7/52 , G01N21/6452 , B01L9/06 , B01L2200/141 , B01L2200/142 , B01L2300/042 , B01L2300/0654 , B01L2300/0829 , B01L2300/0851 , B01L2300/1822
Abstract: An apparatus comprises a thermally conductive receptacle holder including a plurality of receptacle wells configured to receive receptacles, a plurality of optical fibers having first and second ends, wherein each first end is in optical communication with one of the receptacle wells and each second end is in optical communication with an excitation signal source and/or an emission signal detector, one or more thermal elements positioned proximal to the receptacle holder for altering the temperature of the receptacle holder, a heat sink in thermal communication with the receptacle holder, and one or more thermal devices disposed within the heat sink for pre-heating the heat sink.
-
公开(公告)号：US20240060114A1
公开(公告)日：2024-02-22
申请号：US18385300
申请日：2023-10-30
Applicant: Gen-Probe Incorporated
Inventor： David A. BUSE , Norbert D. Hagen , David Opalsky
IPC: C12Q1/6806 , G01N35/04 , B01L3/00 , B01L7/00 , C12Q1/686
CPC classification number: C12Q1/6806 , G01N35/04 , B01L3/50825 , B01L3/565 , B01L7/5255 , C12Q1/686 , G01N2035/0418 , G01N2035/0436 , B01L3/527 , B01L2200/026 , B01L2200/0689 , B01L2300/046
Abstract: A method for reconstituting a reagent within a reagent pack including one or more wells and at least one of the wells containing a lyophilized reagent comprises the steps of receiving reagent packs into a reagent pack input carousel, transferring one reagent pack with a rotary distributor from the input carousel to a reagent pack storage carousel, retrieving the reagent pack from the storage carousel with the rotary distributor and placing the reagent pack into a reagent pack loading station, and dispensing a reconstitution reagent with an automated pipettor into the well containing the lyophilized reagent to form a reconstituted reagent.
-
公开(公告)号：US11809947B2
公开(公告)日：2023-11-07
申请号：US17694436
申请日：2022-03-14
Applicant: GEN-PROBE INCORPORATED
Inventor： Norbert D. Hagen , David Opalsky , Rolf Silbert
CPC classification number: G06K7/10732 , G01N35/00732 , G01N35/026 , G06K7/10811 , G06K7/10861 , G06K7/1413 , G06K7/1417 , G06K7/1447 , G06K19/06028 , G06K19/06037 , G01N2035/00752 , G01N2035/00801 , G01N2035/00831 , G01N2035/00851 , G01N2035/0413 , G01N2035/0493
Abstract: Method and associated system for reading machine-readable labels on a plurality of sample receptacles held by a sample rack. In the method, a machine-readable label associated each of the plurality of sample receptacles is read with a first label reader when the rack is at a first location. The sample rack is then moved from the first location to a second location, where a rack identifier on the sample rack is sensed with a sensor separate from the first label reader. Finally, the rack identifier is associated with the machine-readable labels of the plurality of sample receptacles.
-
公开(公告)号：US11693190B2
公开(公告)日：2023-07-04
申请号：US17144880
申请日：2021-01-08
Applicant: Gen-Probe Incorporated
Inventor： Norbert D. Hagen , David Opalsky
CPC classification number: G02B6/3668 , G01N21/253 , G01N21/6452 , G02B6/06 , G02B6/08 , G02B6/3672 , G02B6/4214 , G02B6/4246 , G02B6/4269 , G01N2021/6484
Abstract: An apparatus for detecting an emission signal from each of a plurality of emission signal sources includes one or more excitation sources configured to generate an excitation light of an excitation wavelength and one or more associated emission detectors configured to detect light of an emission wavelength. A transmission fiber is associated with each of the emission signal sources. A carrier is configured to move the one or more excitation sources and the one or more emission detectors relative to the transmission fibers to sequentially place each emission detector and associated excitation source in an operative position with respect to each transmission fiber. Each transmission fiber transmits both the excitation light from the excitation source and the corresponding emission light to the associated emission detector.
-
Patent Agency Ranking
16.发明授权公开(公告)号：US11692220B2
公开(公告)日：2023-07-04
申请号：US17027433
申请日：2020-09-21
Applicant: Gen-Probe Incorporated
Inventor： David Buse , David Howard Combs , Norbert D. Hagen , David Opalsky , Bruce Richardson , Anita Prasad , Keith Moravick , Tyler Moore , Byron J. Knight
CPC classification number: C12Q1/686 , B01L7/52 , G01N21/6452 , B01L9/06 , B01L2200/141 , B01L2200/142 , B01L2300/042 , B01L2300/0654 , B01L2300/0829 , B01L2300/0851 , B01L2300/1822 , G01N2021/6482 , G01N2021/6484
Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with multiple receptacle wells. Each well has a through-hole extending from an inner surface of the well to an outer surface of the holder. A cover is rotatable between an open position and a closed position relative to the holder and is configured to exert a force onto any receptacles in the wells when the cover is in the closed position. The apparatus includes multiple optical fibers, and each of the optical fibers provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A thermal element is positioned between a thermally-conductive support and the receptacle holder.
-
公开(公告)号：US11275914B2
公开(公告)日：2022-03-15
申请号：US16905816
申请日：2020-06-18
Applicant: GEN-PROBE INCORPORATED
Inventor： Norbert D. Hagen , David Opalsky , Rolf Silbert
Abstract: A method for reading machine-readable labels on a plurality of sample receptacles held by a sample rack. The sample rack is moved between first and second positions within a housing and a label reader is activated at each of a plurality of predetermined position between the first and second positions to read the machine-readable label of each of the plurality of sample receptacles.
-
18.发明授权公开(公告)号：US11230733B2
公开(公告)日：2022-01-25
申请号：US17025735
申请日：2020-09-18
Applicant: Gen-Probe Incorporated
Inventor： David Buse , David Howard Combs , Norbert D. Hagen , David Opalsky , Bruce Richardson , Anita Prasad , Keith Moravick , Tyler Moore , Byron J. Knight
Abstract: Receptacles containing a reaction mixture are transported to receptacle wells of a thermally conductive receptacle holder, and the temperature of the holder is cycled with a thermoelectric device situated between a support and a first side of the holder while a first force is applied onto a second side of the holder. Optical communication between each well and an excitation signal source and an emission signal detector is established to determine whether an emission signal is emitted from any of the receptacles during temperature cycling as an indication of the presence of a target nucleic acid. The thermoelectric device may be situated between an upright portion of the support and the first side of the holder. A second force may be applied onto a top end of each receptacle in the holder by a cover moveable with respect to the receptacles between an open position and a closed position.
-
公开(公告)号：US20210324445A1
公开(公告)日：2021-10-21
申请号：US17146110
申请日：2021-01-11
Applicant: Gen-Probe Incorporated
Inventor： David A. Buse , David Opalsky , Jason F. Rhubottom , Norbert D. Hagen , Jennifer L. Tidd
IPC: C12Q1/6806 , G01N35/04 , B01L3/00 , B01L7/00 , C12Q1/686
Abstract: A diagnostic system is configured to perform first and second, different nucleic acid amplification reactions. The system includes a bulk reagent container compartment configured to store first bulk reagent container containing a first bulk reagent for performing sample preparation processes with a first subset and a second subset of a plurality of samples and a second bulk reagent container containing a second bulk reagent for performing the first nucleic acid amplification reaction. The system includes a unit-dose reagent compartment storing a unit-dose reagent pack including unit-dose reagents for performing the second nucleic acid amplification reaction. The system is configured to perform the sample preparation process using the first bulk reagent on the first and second subsets of the samples, perform the first nucleic acid amplification reaction using the second bulk reagent on the first subset of the samples, and perform the second nucleic acid amplification reaction using the unit-dose reagents on the second subset of the samples.
-
公开(公告)号：US11136617B2
公开(公告)日：2021-10-05
申请号：US17036307
申请日：2020-09-29
Applicant: Gen-Probe Incorporated
Inventor： Byron J. Knight , David A. Buse , Norbert D. Hagen , David Opalsky , Tyler Moore , Anita Prasad , Bruce Richardson
Abstract: A cap that is securable to a vial includes a plug configured for insertion into an open end of the vial. An upper portion of the cap defines a probe recess with an open top end and configured to receive a distal end of a probe of a pipettor inserted into the open top end, to frictionally secure the cap to an end of the probe. The cap includes a radially-oriented annular surface with one or more locking members depending from a periphery of the annular surface. The locking members are spaced from the plug and each locking member includes a radial locking groove and a radial locking ridge beneath the radial locking groove. A lip of the vial snaps into the radial locking groove above the radial locking ridge to secure the cap to the vial when the plug is inserted into the open end of the vial.
-
-
-
-
-
-
-
-
-
Search Results
74
records
(took 0.019 seconds)
