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公开(公告)号:US20240150823A1
公开(公告)日:2024-05-09
申请号:US18544053
申请日:2023-12-18
Applicant: Gen-Probe Incorporated
Inventor: David BUSE , David Howard COMBS , Norbert D. HAGEN , David OPALSKY , Bruce RICHARDSON , Anita PRASAD , Keith MORAVICK , Tyler MOORE , Byron J. Knight
CPC classification number: C12Q1/686 , B01L7/52 , G01N21/6452 , B01L9/06 , B01L2200/142 , B01L2300/0654 , B01L2300/0829 , B01L2300/0851 , B01L2300/1822 , G01N2021/6484
Abstract: An apparatus for incubating a plurality of receptacles includes one or more thermally-conductive receptacle holders, each comprising a plurality of receptacle wells. A thermally-conductive support is associated with each of the receptacle holders, and a thermal element is positioned between the associated support and the receptacle holder. A heat sink is in thermal communication with the support and comprises a plurality of spaced-apart fins. An optical fiber associated with each receptacle well has a first end positioned adjacent to or within a through-hole formed in the receptacle well and extends through through-holes formed in the support and the heat sink aligned with the through-hole of the receptacle well. Each of the optical fibers is positioned between two adjacent fins of the plurality of fins.
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公开(公告)号:US20180250970A1
公开(公告)日:2018-09-06
申请号:US15971660
申请日:2018-05-04
Applicant: Gen-Probe Incorporated
Inventor: Rolf SILBERT , Robert ROSATI , David BUSE , Olev TAMMER , Matthias MERTEN
Abstract: A printing module configured to print a label on a curved surface of an article includes an expandable printing mechanism configured to be expanded to an open configuration for receiving the article or contracted to a closed configuration placing the curved surface in an operative position with respect to a print head and an article moving assembly configured to grasp and hold the article and effect relative movement between the curved surface and the print head. The printing mechanism includes contact elements, such as rollers, that contact or otherwise engage the article when the printing mechanism is in the closed configuration and maintain the curved surface in the operative position with respect to the print head during relative movement between the curved surface and the print head.
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公开(公告)号:US20210299664A1
公开(公告)日:2021-09-30
申请号:US17210040
申请日:2021-03-23
Applicant: Gen-Probe Incorporated
Inventor: David BUSE , Byron J. Knight
Abstract: A container includes a base with a top wall, a vessel depending from a top wall aperture in the top wall, a fluid retainer projecting above the top wall and surrounding the top wall aperture, and a skirt surrounding the vessel and including opposed grooves for gripping the container. A lid is disposed on a top end of the base and includes a cover wall with a lid aperture generally aligned with the top wall aperture of the base. A septum is disposed between the top wall of the base and the cover wall with a portion of the septum disposed between the lid aperture and the top wall aperture. Fluid retainer/return structure is configured to prevent fluid deposited on the septum from dripping off the container and to allow at least a portion of the fluid deposited on the septum to run off the septum and into the vessel.
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公开(公告)号:US20210062245A1
公开(公告)日:2021-03-04
申请号:US17027363
申请日:2020-09-21
Applicant: Gen-Probe Incorporated
Inventor: David BUSE , David Howard COMBS , Norbert D. HAGEN , David OPALSKY , Bruce RICHARDSON , Anita PRASAD , Keith MORAVICK , Tyler MOORE , Byron J. Knight
Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder that includes multiple receptacle wells. Each well can receive a receptacle and has a through-hole extending from an inner surface of the well to an outer surface of the holder. The apparatus includes multiple optical fibers, and each optical fiber has a first end in optical communication with an associated well and a second end in optical communication with an excitation signal source and/or an emission signal detector. The first end of each optical fiber is moveable with respect to the through-hole. A cover is movable between an open position and a closed position relative to the receptacle holder, and the first end of each optical fiber moves with respect to the through-hole of the associated well as the cover moves to the open or closed position or when the cover moves into or out of contact with any receptacles within the wells.
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公开(公告)号:US20170259258A1
公开(公告)日:2017-09-14
申请号:US15604791
申请日:2017-05-25
Applicant: GEN-PROBE INCORPORATED
Inventor: David BUSE , Byron J. KNIGHT , Julian GROELI
IPC: B01L3/00 , B65B69/00 , B65D1/02 , B65D1/34 , B65D39/00 , C12Q1/68 , G01N35/02 , G01N35/10 , G01N30/60 , G01N35/00
CPC classification number: B01L3/5085 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1002 , G01N35/1079 , G01N2035/00287 , Y10T436/11
Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
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公开(公告)号:US20150362515A1
公开(公告)日:2015-12-17
申请号:US14837647
申请日:2015-08-27
Applicant: GEN-PROBE INCORPORATED
Inventor: David BUSE , Byron J. KNIGHT
IPC: G01N35/02
CPC classification number: B01L3/5085 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1002 , G01N35/1079 , G01N2035/00287 , Y10T436/11
Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
Abstract translation: 提供了用于执行基于自动化试剂的分析的系统,装置和方法。 还提供了用于将盖自动附接到反应容器的方法,以及从加盖的反应容器自动移除盖。
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公开(公告)号:US20220105739A1
公开(公告)日:2022-04-07
申请号:US17396525
申请日:2021-08-06
Applicant: GEN-PROBE INCORPORATED
Inventor: Rolf SILBERT , Robert J. ROSATI , David BUSE , Olev TAMMER , Matthias MERTEN
Abstract: A method for controlling a printing process by which a print head prints an image onto predetermined printable area of a label.
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公开(公告)号:US20210032681A1
公开(公告)日:2021-02-04
申请号:US17028367
申请日:2020-09-22
Applicant: Gen-Probe Incorporated
Inventor: David BUSE , David Howard COMBS , Nobert D. HAGEN , David OPALSKY , Bruce RICHARDSON , Anita PRASAD , Keith MORAVICK , Tyler MOORE , Byron J. KNIGHT
Abstract: Multiple receptacles containing a reaction mixture are transported to corresponding receptacle wells of a thermally-conductive receptacle holder in thermal communication with a support that is in thermal communication with a heat sink. The heat sink is pre-heated to a temperature above ambient temperature, and the temperature of the receptacle holder is cycled. Optical communication is established between each of the receptacle wells and an excitation signal source and an emission signal detector during cycling, and whether an emission signal is emitted from any of the receptacles is determined as an indication of the presence of a target nucleic acid.
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公开(公告)号:US20210002705A1
公开(公告)日:2021-01-07
申请号:US17027433
申请日:2020-09-21
Applicant: Gen-Probe Incorporated
Inventor: David BUSE , David Howard COMBS , Norbert D. HAGEN , David OPALSKY , Bruce RICHARDSON , Anita PRASAD , Keith MORAVICK , Tyler MOORE , Byron J. Knight
Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with multiple receptacle wells. Each well has a through-hole extending from an inner surface of the well to an outer surface of the holder. A cover is rotatable between an open position and a closed position relative to the holder and is configured to exert a force onto any receptacles in the wells when the cover is in the closed position. The apparatus includes multiple optical fibers, and each of the optical fibers provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A thermal element is positioned between a thermally-conductive support and the receptacle holder.
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公开(公告)号:US20140271360A1
公开(公告)日:2014-09-18
申请号:US14210105
申请日:2014-03-13
Applicant: GEN-PROBE INCORPORATED
Inventor: David BUSE , Byron J. KNIGHT , Julian GROELI
CPC classification number: B01L3/5085 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1002 , G01N35/1079 , G01N2035/00287 , Y10T436/11
Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
Abstract translation: 提供了用于执行基于自动化试剂的分析的系统,装置和方法。 还提供了用于将盖自动附接到反应容器的方法,以及从加盖的反应容器自动移除盖。
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