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公开(公告)号：US11602630B2
公开(公告)日：2023-03-14
申请号：US16002992
申请日：2018-06-07
Applicant: NeuroNexus Technologies, Inc.
Inventor： Rio J. Vetter , Peter Gerow , David S. Pellinen , Carlos Rackham , Daryl R. Kipke , Jamille F. Hetke
Abstract: A medical electrode array system comprising a thin-film substrate, a plurality of electrode contacts disposed on the thin-film substrate, and a plurality of traces. The plurality of electrode contacts is configured to provide electrical contact points. The plurality of traces is electrically connected to the plurality of electrode contacts. A electrode contact of the plurality of electrode contacts has a dedicated trace of the plurality of traces that provides electrical connectivity to the electrode contact. The thin-film substrate is configured to flex to maintain continuous contact with contours of patient anatomy. The plurality of traces includes flexible spring-like portions to add flexibility to the thin-film substrate.
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公开(公告)号：US10252047B2
公开(公告)日：2019-04-09
申请号：US14685661
申请日：2015-04-14
Applicant: NeuroNexus Technologies, Inc.
Inventor： John P. Seymour , Jamille Farraye Hetke , Rio J. Vetter , Daryl R. Kipke , David S. Pellinen , Kc Kong
Abstract: The neural interface system of one embodiment includes a cylindrical shaft, a lateral extension longitudinally coupled to at least a portion of the shaft and having a thickness less than a diameter of the shaft, and an electrode array arranged on the lateral extension and radially offset from the shaft, including electrode sites that electrically interface with their surroundings. The method of one embodiment for making the neural interface system includes forming a planar polymer substrate with at least one metallization layer, patterning on at least one metallization layer an electrode array on a first end of the substrate, patterning conductive traces on at least one metallization layer, rolling a portion of the substrate toward the first end of the substrate, and securing the rolled substrate into a shaft having the first end of the substrate laterally extending from the shaft and the electrode array radially offset from the shaft.
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公开(公告)号：US20190021618A1
公开(公告)日：2019-01-24
申请号：US16048948
申请日：2018-07-30
Applicant: NeuroNexus Technologies, Inc.
Inventor： Jamille Farraye Hetke , Daryl R. Kipke , Rio J. Vetter
Abstract: An implantable device for body tissue, including an electrical subsystem that flexes within and interfaces with body tissue and a carrier that operates in the following two modes: provides structural support for the electrical subsystem during implantation of the device in body tissue and allows flexing of the electrical subsystem after implantation of the device in body tissue. The implantable device is preferably designed to be implanted into the brain, spinal cord, peripheral nerve, muscle, or any other suitable anatomical location. The implantable device, however, may be alternatively used in any suitable environment and for any suitable reason.
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公开(公告)号：US09289151B2
公开(公告)日：2016-03-22
申请号：US14623991
申请日：2015-02-17
Applicant: NeuroNexus Technologies, Inc.
Inventor： Daryl R. Kipke , Jamille Farraye Hetke , Rio J. Vetter , John P. Seymour
IPC: A61N1/05 , A61B5/0478 , A61N1/36 , A61B5/04 , A61B5/00
CPC classification number: A61B5/0478 , A61B5/04001 , A61B5/686 , A61B5/6868 , A61B2562/187 , A61N1/05 , A61N1/0529 , A61N1/0539 , A61N1/0551 , A61N1/36
Abstract: An improved deformable carrier or connector for an implantable neural interface device is described. The neural interface device comprises a carrier supporting at least one electrode array. The carrier comprises a tubular sidewall extending from a proximal carrier portion to a distal carrier portion. At least one deformable segment is provided in the carrier sidewall. The deformable segment is more pliable than the remainder of the carrier sidewall to preferably move in response to forces imparted on the carrier and the electrode array by the shifting forces in body tissue. The deformable segment takes the form of a thinned sidewall segment or a slitted wall segment.
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公开(公告)号：US20150047179A1
公开(公告)日：2015-02-19
申请号：US14521552
申请日：2014-10-23
Applicant: NeuroNexus Technologies, Inc.
Inventor： John P. Seymour , Mayurachat Ning Gulari , Daryl R. Kipke , Kc Kong
CPC classification number: A61N5/0622 , A61B5/0084 , A61B5/04001 , A61B5/4076 , A61B2562/0233 , A61B2562/046 , A61N2005/0626 , A61N2005/0643 , Y10T29/49016
Abstract: A waveguide neural interface device including: a neural device implantable in tissue and including an array of electrode sites that electrically communicate with their surroundings, in which the array of electrode sites includes at least one recording electrode site; and a waveguide, coupled to the neural device, that carries light along a longitudinal axis and includes a light directing element that redirects the carried light from the waveguide to illuminate selectively targeted tissue, in which at least a portion of the redirected light is directed laterally away from the longitudinal axis and the recording electrode site is configured to sample illuminated tissue. A method for assembling a waveguide neural interface device is also described.
Abstract translation: 一种波导神经接口装置，包括：可植入组织中并包括与其周围环境电连通的电极位置阵列的神经装置，其中电极位置阵列包括至少一个记录电极位置; 以及耦合到所述神经装置的波导，其沿着纵向轴线承载光，并且包括导光元件，所述光导向元件重新导向所述被传输的光从所述波导照射选择性地靶向的组织，其中所述重定向的光的至少一部分被侧向 远离纵向轴线并且记录电极部位被配置为对照射的组织进行采样。 还描述了一种用于组装波导神经接口装置的方法。
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Patent Agency Ranking
公开(公告)号：US10688298B2
公开(公告)日：2020-06-23
申请号：US15600877
申请日：2017-05-22
Applicant: NeuroNexus Technologies, Inc.
Inventor： David S. Pellinen , Mayurachat Ning Gulari , Jamille Farraye Hetke , David J. Anderson , Daryl R. Kipke , Rio J. Vetter
Abstract: An implantable electrode system of is disclosed that includes a conductive electrode layer, an interconnect coupled to the electrode layer, an insulator that insulates the interconnect, and an anchor that more securely fixes the electrode layer in place. This structure is particularly useful with the electrode layer being a neural interface that is configured to provide either a recording or stimulating function. A method for forming such an implantable electrode system includes forming an interconnect over a base layer, forming an anchoring structure over the base layer, depositing an insulating material layer over the interconnect structure and over the anchoring structure, exposing a portion of the interconnect structure, forming an electrode layer over the insulating layer, the electrode layer contacting the exposed portion of the interconnect structure.
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公开(公告)号：US20190298993A1
公开(公告)日：2019-10-03
申请号：US16241230
申请日：2019-01-07
Applicant: NeuroNexus Technologies, Inc.
Inventor： David S. Pellinen , Bencharong Suwarato , Rio J. Vetter , Jamille Farraye Hetke , Daryl R. Kipke
Abstract: A neural probe comprising an array of stimulation and/or recording electrodes supported on a tape spring-type carrier is described. The neural probe comprising the tape spring-type carrier is used to insert flexible electrode arrays straight into tissue, or to insert them off-axis from the initial penetration of a guide tube. Importantly, the neural probe is not rigid, but has a degree of stiffness provided by the tape spring-type carrier that maintains a desired trajectory into body tissue, but will subsequently allow the probe to flex and move in unison with movement of the body tissue.
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公开(公告)号：US20180353753A1
公开(公告)日：2018-12-13
申请号：US16002992
申请日：2018-06-07
Applicant: NeuroNexus Technologies, Inc.
Inventor： Rio J. Vetter , Peter Gerow , David S. Pellinen , Carlos Rackham , Daryl R. Kipke , Jamille F. Hetke
CPC classification number: A61N1/0553 , A61B5/04001 , A61B5/0422 , A61B5/6869 , A61B5/6883 , A61B2562/0209 , A61B2562/046 , A61B2562/164 , A61B2562/166 , A61B2562/222 , A61N1/0558 , A61N1/059 , A61N1/0597 , A61N1/36114
Abstract: A medical electrode array system comprising a thin-film substrate, a plurality of electrode contacts disposed on the thin-film substrate, and a plurality of traces. The plurality of electrode contacts is configured to provide electrical contact points. The plurality of traces is electrically connected to the plurality of electrode contacts. A electrode contact of the plurality of electrode contacts has a dedicated trace of the plurality of traces that provides electrical connectivity to the electrode contact. The thin-film substrate is configured to flex to maintain continuous contact with contours of patient anatomy. The plurality of traces includes flexible spring-like portions to add flexibility to the thin-film substrate.
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公开(公告)号：US10118030B2
公开(公告)日：2018-11-06
申请号：US14519346
申请日：2014-10-21
Applicant: NeuroNexus Technologies, Inc.
Inventor： David S. Pellinen , Bencharong Suwarato , Rio J. Vetter , Jamille Farraye Hetke , Daryl R. Kipke
Abstract: A neural probe system having a single guide tube that is inserted into neural tissue and from which a number of neural probes can be deployed is described. Each probe is deployable into tissue along a desired trajectory. This is done by supporting the electrode array on a spring tape-type carrier that maintains axial stiffness once the neural probe has deployed out a channel in the guide tube. That way, a target neural tissue is bounded by an increased number of neural probes while minimizing trauma to surrounding body tissue.
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公开(公告)号：US20150164360A1
公开(公告)日：2015-06-18
申请号：US14623991
申请日：2015-02-17
Applicant: NeuroNexus Technologies, Inc
Inventor： Daryl R. Kipke , Jamille Farraye Hetke , Rio J. Vetter , John P. Seymour
IPC: A61B5/0478 , A61N1/05
CPC classification number: A61B5/0478 , A61B5/04001 , A61B5/686 , A61B5/6868 , A61B2562/187 , A61N1/05 , A61N1/0529 , A61N1/0539 , A61N1/0551 , A61N1/36
Abstract: An improved deformable carrier or connector for an implantable neural interface device is described. The neural interface device comprises a carrier supporting at least one electrode array. The carrier comprises a tubular sidewall extending from a proximal carrier portion to a distal carrier portion. At least one deformable segment is provided in the carrier sidewall. The deformable segment is more pliable than the remainder of the carrier sidewall to preferably move in response to forces imparted on the carrier and the electrode array by the shifting forces in body tissue. The deformable segment takes the form of a thinned sidewall segment or a slitted wall segment.
Abstract translation: 描述了用于可植入神经接口装置的改进的可变形载体或连接器。 神经接口装置包括支撑至少一个电极阵列的载体。 载体包括从近端载体部分延伸到远端载体部分的管状侧壁。 至少一个可变形段设置在承载器侧壁中。 可变形部分比载体侧壁的其余部分更柔韧，优选地响应于通过身体组织中的移动力施加在载体和电极阵列上的力而移动。 可变形段采取变薄的侧壁段或切开的壁段的形式。
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