LOW TEMPERATURE SPRAY DRYING OF CARRIER-FREE COMPOSITIONS

    公开(公告)号:US20210101125A1

    公开(公告)日:2021-04-08

    申请号:US17109005

    申请日:2020-12-01

    Abstract: A spray drying process and apparatus for drying a spray dryable liquid composition to a spray dried powder is described, in which the spray dryable liquid composition contains no carrier. The spray dryable liquid composition is processed at a solids concentration not exceeding 80% by weight, based on total weight of the spray dryable liquid composition, being atomized to generate an atomized spray of liquid particles of the spray dryable liquid composition into a spray drying chamber, in which the atomized spray is contacted with a stream of drying fluid flowed at temperature not exceeding 100° C. into the spray drying chamber, to form the spray dried powder.

    LOW TEMPERATURE SPRAY DRYING OF CARRIER-FREE COMPOSITIONS

    公开(公告)号:US20200206707A1

    公开(公告)日:2020-07-02

    申请号:US16800961

    申请日:2020-02-25

    Abstract: A spray drying process and apparatus for drying a spray dryable liquid composition to a spray dried powder is described, in which the spray dryable liquid composition contains no carrier. The spray dryable liquid composition is processed at a solids concentration not exceeding 80% by weight, based on total weight of the spray dryable liquid composition, being atomized to generate an atomized spray of liquid particles of the spray dryable liquid composition into a spray drying chamber, in which the atomized spray is contacted with a stream of drying fluid flowed at temperature not exceeding 100° C. into the spray drying chamber, to form the spray dried powder.

    Ultrahigh efficiency spray drying apparatus and process

    公开(公告)号:US10155234B1

    公开(公告)日:2018-12-18

    申请号:US16005302

    申请日:2018-06-11

    Abstract: The disclosure relates to ultrahigh efficiency spray drying systems and processes, utilizing induction of localized turbulence in a drying fluid flow stream to produce spray dried product, having particular utility for low temperature spray drying operations. In a specific implementation, a method of processing a spray dryable liquid composition to form a spray dried product includes the steps of: generating a spray of the spray dryable liquid composition; contacting the spray of spray dryable liquid composition in a spray drying contact zone with a stream of primary drying fluid; injecting pressurized secondary drying fluid into the stream of primary drying fluid in the spray drying contact zone at multiple loci thereof to provide localized turbulence at said multiple loci; and recovering the spray dried product from the spray drying contact zone. Systems of the present disclosure are effective in achieving high-rate production of dry powder spray dried products, with substantially reduced capital equipment costs, energy requirements, and operating expenditures.

    Methods and apparatus for low heat spray drying
    14.
    发明授权
    Methods and apparatus for low heat spray drying 有权
    低热喷雾干燥的方法和装置

    公开(公告)号:US09551527B2

    公开(公告)日:2017-01-24

    申请号:US15092561

    申请日:2016-04-06

    Abstract: Methods and apparatus provide for spray drying a liquid product into a dried powder without applying heat, including: forming a slurry including a liquid solvent, a carrier, and an active ingredient; applying an electrostatic charge to the slurry; atomizing the charged slurry to produce a plurality of electrostatically charged, wet particles; suspending the electrostatically charged, wet particles for a sufficient time to permit repulsive forces induced by the electrostatic charge on at least some wet particles to cause at least some of such particles to divide into wet sub-particles; and continuing the suspending step, without the presence of any heated drying fluids, for a sufficient time to drive off a sufficient amount of the liquid solvent within most of the wet particles to leave a plurality of dried particles (the powder), each dried particle containing the active ingredient encapsulated within the carrier.

    Abstract translation: 方法和装置提供将液体产物喷雾干燥成干燥粉末而不施加热量,包括:形成包括液体溶剂,载体和活性成分的浆料; 对浆料施加静电荷; 雾化带电的浆料以产生多个带静电的湿颗粒; 将静电带电的湿颗粒悬浮足够的时间以允许由至少一些湿颗粒上的静电电荷引起的排斥力使至少一些这样的颗粒分成湿的亚颗粒; 并且在没有任何加热的干燥流体的情况下继续悬浮步骤足够的时间以排出大部分湿颗粒中的足够量的液体溶剂以留下多个干燥颗粒(粉末),每个干燥颗粒 含有包封在载体内的活性成分。

    METHODS AND APPARATUS FOR LOW HEAT SPRAY DRYING
    15.
    发明申请
    METHODS AND APPARATUS FOR LOW HEAT SPRAY DRYING 有权
    低热喷雾干燥的方法和装置

    公开(公告)号:US20160223255A1

    公开(公告)日:2016-08-04

    申请号:US15092561

    申请日:2016-04-06

    Abstract: Methods and apparatus provide for spray drying a liquid product into a dried powder without applying heat, including: forming a slurry including a liquid solvent, a carrier, and an active ingredient; applying an electrostatic charge to the slurry; atomizing the charged slurry to produce a plurality of electrostatically charged, wet particles; suspending the electrostatically charged, wet particles for a sufficient time to permit repulsive forces induced by the electrostatic charge on at least some wet particles to cause at least some of such particles to divide into wet sub-particles; and continuing the suspending step, without the presence of any heated drying fluids, for a sufficient time to drive off a sufficient amount of the liquid solvent within most of the wet particles to leave a plurality of dried particles (the powder), each dried particle containing the active ingredient encapsulated within the carrier.

    Abstract translation: 方法和装置提供将液体产物喷雾干燥成干燥粉末而不施加热量,包括:形成包括液体溶剂,载体和活性成分的浆料; 对浆料施加静电荷; 雾化带电的浆料以产生多个带静电的湿颗粒; 将静电带电的湿颗粒悬浮足够的时间以允许由至少一些湿颗粒上的静电电荷引起的排斥力使至少一些这样的颗粒分成湿的亚颗粒; 并且在没有任何加热的干燥流体的情况下继续悬浮步骤足够的时间以排出大部分湿颗粒中的足够量的液体溶剂以留下多个干燥颗粒(粉末),每个干燥颗粒 含有包封在载体内的活性成分。

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