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公开(公告)号：US20180221877A1
公开(公告)日：2018-08-09
申请号：US15945272
申请日：2018-04-04
Applicant: TOPPAN PRINTING CO., LTD.
Inventor： Keisuke Goto , Yoichi Makino , Akihiro Hoshino
CPC classification number: B01L3/502715 , B01L7/52 , B01L2300/046 , B01L2300/0829 , B01L2300/0877 , B01L2300/0887 , B01L2300/161 , B81B1/006 , B81B3/0083 , B81B2201/057 , B81B2201/058 , B81B2203/0338 , B81B2203/0353 , G01N21/03 , G01N21/6428 , G01N21/6452 , G01N33/52 , G01N2021/6439
Abstract: A microfluidic device includes: a base plate allowing an electromagnetic wave to pass therethrough and having no autofluorescence; a microwell array formed on the base plate and including a wall layer in which a plurality of through-holes are formed in a thickness direction; and a lid member disposed opposite to the base plate in a state of being separated from the wall layer, wherein microwells are formed by the base plate and the through-holes formed in the wall layer, and wherein the wall layer is formed of a material containing a colored component that absorbs an electromagnetic wave of a predetermined wavelength.
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公开(公告)号：US09968930B2
公开(公告)日：2018-05-15
申请号：US14780262
申请日：2014-03-26
Applicant: SURNETICS, LLC
Inventor： Brian David Babcock
CPC classification number: B01L3/50273 , B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L2200/06 , B01L2300/0627 , B01L2300/0816 , B01L2300/16 , B01L2300/161 , B01L2400/0406 , B01L2400/0493 , B01L2400/088 , B81B2201/058 , B81C1/00206
Abstract: A microfluidic product utilizing gradient surface energy coatings for fluid control comprising a plurality of fluid passages wherein at least one fluid passage comprises a coating configured to control liquid flow wherein the coating configured to control liquid flow comprises a gradient surface energy coating from a proximal location to a distal location on a surface of the fluid passage. The product can include uniform regions and surface gradient regions in the same passage. Coating compositions and product dimensions can be selected to provide control over different flow properties including fluid velocity, reduction and acceleration of fluid flow, and starting and stopping fluid flow.
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公开(公告)号：US09938139B2
公开(公告)日：2018-04-10
申请号：US15033015
申请日：2013-10-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Roger A. McKay , Patrick W. Sadik
CPC classification number: B81C1/00539 , B81B2201/058 , B81C1/00119 , B81C2201/0115 , B81C2201/014 , C23C14/5873 , C23F1/02 , C23F1/16 , H01M4/0492 , H01M4/386
Abstract: Etching islands are formed on a first face of a substrate and a second face of the substrate non-parallel to the first face. The first face and the second face of the substrate are concurrently exposed to a solution that reacts with the etching islands to concurrently form porous regions extending into the first face and the second face.
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公开(公告)号：US20180085755A1
公开(公告)日：2018-03-29
申请号：US15277889
申请日：2016-09-27
Applicant: International Business Machines Corporation
Inventor： Jaione Tirapu Azpiroz , Peter William Bryant , Rodrigo Neumann Barros Ferreira , Ronaldo Giro , Ricardo Luis Ohta
CPC classification number: B01L3/502746 , B01L3/502707 , B01L3/502715 , B01L3/502761 , B01L2200/06 , B01L2200/0652 , B01L2200/0668 , B01L2200/12 , B01L2300/0645 , B01L2300/123 , B01L2400/0661 , B01L2400/082 , B01L2400/086 , B81B1/006 , B81B2201/058 , B81B2203/0361 , B81C1/00111 , F16B1/0014
Abstract: A microfluidic device, including a substrate including a microchannel, an activation setup disposed in the microchannel, and a matrix array of controllable shape-changing micropillars connected to the activation setup. A shape of the controllable shape-changing micropillars changes based on an activation of the activation setup.
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公开(公告)号：US20180035490A1
公开(公告)日：2018-02-01
申请号：US15727589
申请日：2017-10-07
Applicant: CELL ID PTE LTD
Inventor： Lye Hock SIM
CPC classification number: H05B3/34 , B01J2219/00495 , B01J2219/00533 , B01L3/502715 , B01L3/502784 , B01L3/505 , B01L3/50825 , B01L3/50851 , B01L3/50855 , B01L7/52 , B01L2300/0887 , B01L2300/0893 , B01L2300/0896 , B01L2300/123 , B01L2300/1805 , B01L2300/1827 , B81B7/0083 , B81B2201/058 , H05B3/267 , H05B2203/002 , H05B2203/003
Abstract: A digital PCR device comprising: a discrete heating area made of a heat conductive material disposed on a surface that is electrically non-conductive, the discrete heating area comprising a plurality of integral wells configured to contain and partition a DNA sample therein; and at least one conductive trace configured to be connected to a dc voltage source and to heat the plurality of integral wells to a uniform temperature when connected to the dc voltage source, the at least one conductive trace disposed on the surface in an undulating configuration at least partially around the discrete heating area.
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Patent Agency Ranking
公开(公告)号：US20170203566A1
公开(公告)日：2017-07-20
申请号：US15479618
申请日：2017-04-05
Inventor： Jennifer A. Lewis , Christopher J. Hansen , Steven Kranz , John J. Vericella , Willie Wu , David B. Kolesky
CPC classification number: B41J2/1433 , B29C64/112 , B29C64/20 , B41J2/14 , B41J2/1623 , B81B2201/058
Abstract: A multinozzle deposition system for direct write applications comprises a body including a first network of microchannels embedded therein, where the first network of microchannels extends from a parent microchannel through a series of furcations to a plurality of branching microchannels. The series consists of k generations with furcation number m where the kth generation includes mk branching microchannels. A first end of the body includes a single inlet to the parent microchannel and a second end of the body includes mk outlets from the branching microchannels, where k is an integer greater than or equal to 1 and m is an integer greater than or equal to 2. The body comprises a material having a sufficient rigidity to sustain a pressure in the microchannels of about 690 kPa or greater without distortion.
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公开(公告)号：US20170144152A1
公开(公告)日：2017-05-25
申请号：US15380954
申请日：2016-12-15
Applicant: The Regents of the University of California
Inventor： Michelle Khine , Chi-Shuo Chen , Anthony Grimes , David Nate Breslauer , Luke Lee , Michael Dunlap , Ajay Gopinathan , Sayantani Ghosh
CPC classification number: B01L3/502707 , B01F5/0057 , B01F5/0646 , B01F5/0647 , B01F13/0059 , B01F2215/0037 , B01L2200/12 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B81B1/002 , B81B2201/051 , B81B2201/058 , B81B2203/0338 , B81C1/00071 , B81C2201/0152 , B82Y40/00 , G03F7/0002 , H01L21/02269 , H01L21/02271
Abstract: A method is provided to prepare one or more microfluidic channels on a receptive material by applying an image-forming material to a heat sensitive thermoplastic receptive material in a designed pattern and heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%. In an alternative aspect, the microfluidic channels on receptive material are prepared by etching a designed pattern into a heat sensitive thermoplastic material support and then heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%.
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公开(公告)号：US09651548B2
公开(公告)日：2017-05-16
申请号：US14268561
申请日：2014-05-02
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Ximin He , Michael Aizenberg
IPC: G01N33/543 , B81B3/00 , B01L3/00 , G05D23/02 , C12P1/02 , C12P3/00 , C12Q1/66 , G01N33/58 , G01N33/86
CPC classification number: G01N33/54366 , B01L3/5027 , B01L2300/0636 , B01L2300/0877 , B01L2300/1822 , B01L2400/084 , B81B3/0032 , B81B2201/058 , C12P1/02 , C12P3/00 , C12Q1/66 , G01N33/582 , G01N33/86 , G05D23/021
Abstract: A chemo-mechano-chemical (C1-M-C2) system includes a base supporting an actuatable structure, said structure comprising a functionalized portion and being embedded in an environmentally responsive gel capable of volume change in response to an environmental stimulus; a first fluid layer disposed over the base and in contact with the actuatable structure, said first fluid layer comprising the environmentally responsive gel; and a second fluid layer in contact with the actuatable structure, wherein the layers are positioned such that the functionalized portion is in contact with the second layer in a first relaxed state and in contact with the first layer in a second actuated state and wherein the functionalized portion interacts with at least one of the layers to provide a chemical or physical response.
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19.发明申请公开(公告)号：US20170100716A1
公开(公告)日：2017-04-13
申请号：US15293134
申请日：2016-10-13
Applicant: The Regents of the University of Michigan
Inventor： Jong G. Ok , Lingjie J. Guo , Long Chen , Ashwin Panday
IPC: B01L3/00
CPC classification number: B01L3/502707 , B01L3/502761 , B01L2200/0668 , B01L2200/12 , B01L2300/0877 , B01L2300/0893 , B01L2300/16 , B01L2400/0487 , B81B2201/058 , B81B2203/033 , B81C1/00031 , B81C1/0046
Abstract: Methods of forming two-dimensional nanopatterns are provided. The method may comprise periodically contacting a vibrating tool comprising a patterned grating edge with a substrate along a first direction in a grating-vibrational indentation patterning process. The patterned grating edge defines a plurality of rows and a plurality of interspersed troughs. The periodic contacting creates a two dimensional array of discontinuous voids in a single-stroke across the surface of the substrate. In other aspects, a microfluidic device for selective arrangement of a microspecies or nanospecies is provided, that includes a substrate comprising a surface defining a two-dimensional pattern of microvoids or nanovoids. In yet other aspects, the present disclosure provides a method for selective arrangement of a microspecies or nanospecies on a substrate.
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公开(公告)号：US20170044002A1
公开(公告)日：2017-02-16
申请号：US15305467
申请日：2015-04-22
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor： Takahiko HARIYAMA , Daisuke ISHII , Masatsugu SHIMOMURA , Ko OKUMURA , Marie TANI
CPC classification number: B01L3/5027 , B01L3/50273 , B01L3/502746 , B01L2300/0816 , B01L2300/0838 , B01L2300/0858 , B01L2300/087 , B01L2300/0877 , B01L2400/0406 , B01L2400/086 , B81B1/00 , B81B2201/058 , B81B2203/0392 , F16K99/0017 , F16K99/0021 , Y10T137/206 , Y10T137/2224 , Y10T137/85938
Abstract: A combined-blade-type open flow path device being a fluid flow path device where a plurality of flow paths are adjacent to each other, the combined-blade-type open flow path device comprising: a substrate configured to constitute a bottom portion of the flow paths; and a plurality of blades erected on a surface of the substrate, the plurality of blades configured to constitute side walls of the flow paths, wherein the plurality of blades are erected in a plurality of numbers at a space in a direction from an upstream side to a downstream side of a flow of the fluid, and conduction of the fluid between the flow paths adjacent at the space is made possible, and wherein the flow of the fluid is made possible by one end of the flow path being in contact with the fluid.
Abstract translation: 一种组合刀片式开放流路装置，其是多个流路彼此相邻的流体流路装置，所述组合叶片型开放流路装置包括：基板，其构成为构成所述 流路; 以及多个叶片，其竖立在所述基板的表面上，所述多个叶片构造成构成所述流路的侧壁，其中，所述多个叶片在从上游侧到 流体的流动的下游侧和在空间相邻的流动路径之间的流体的传导成为可能，并且其中流体的流动可以由流动路径的一端与流体接触 。
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