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    Method and Device for Determining a Damage Characteristic Value of a Kidney
    192.
    发明申请
    Method and Device for Determining a Damage Characteristic Value of a Kidney 有权
    用于确定肾脏损伤特征值的方法和装置

    公开(公告)号：US20150223744A1

    公开(公告)日：2015-08-13

    申请号：US14432204

    申请日：2013-09-11

    Applicant: SIEMENS AKTINGESELLSCHAFT

    Inventor： Ali-Nejat Bengi ,  Stefan Lautenschläger

    IPC: A61B5/20 ,  A61B6/00

    CPC classification number: A61B5/201 ,  A61B6/461 ,  A61B6/481 ,  A61B6/504 ,  A61B6/5217 ,  G06T7/0016 ,  G06T7/11 ,  G06T2207/10072 ,  G06T2207/30084 ,  G06T2207/30104

    Abstract: The invention relates to elements of a method (1) for determining a damage characteristic value of a kidney (2). Images comprising the kidney (2) and the kidney artery (3) are entered into the method (1), from a three-dimensional digital subtraction angiography which is carried out by administering a contrast medium at the proximal end of the kidney artery (3) and comprises a fill run and a mask run, said method (1) comprising the following method steps: S1) determining a parenchymal blood volume into which the subtractions from images of the fill run and the mask run of the three-dimensional digital subtraction angiography are entered, additionally determining an arterial input function and normalising the parenchymal blood volume with said arterial input function; S2) segmenting the kidney (2), determining an average normalised parenchymal blood volume value, and determining a total value of the parenchymal blood volume into which the normalised parenchymal blood volume values of the segmentation of the kidney (2) are entered; S3) receiving an average normalised parenchymal blood volume normal value and a total normal value for a parenchymal blood volume, and determining at least one damage characteristic value of the kidney (2) into which the average normalised parenchymal blood volume value and the average normalised parenchymal blood volume normal value and/or the total value of the parenchymal blood volume and the total normal value of a parenchymal blood volume are entered; S4) issuing the at least one damage characteristic value of the kidney (2).

    Abstract translation: 本发明涉及用于确定肾脏（2）的损伤特征值的方法（1）的元件。 通过在肾动脉近端施用造影剂（3）进行的三维数字减影血管造影术将包括肾脏（2）和肾动脉（3）的图像输入到方法（1）中 ），并且包括填充运行和掩模运行，所述方法（1）包括以下方法步骤：S1）确定从三维数字减法的填充运行和掩模运行的图像中减去的实质血液体积 输入血管造影术，另外确定动脉输入功能并用所述动脉输入功能标准化实质血液体积; S2）分割肾脏（2），确定平均标准化实质血容量值，并确定进入肾脏（2）的分割的归一化实质血液体积值的实质血容量的总值; S3），接受平均标准化实质血容量正常值和实质血容量的总正常值，并确定肾脏（2）的至少一个损伤特征值，平均标准化实质血容量值和平均标准化实质 输入血液体积正常值和/或实质血容量的总值和实质血容量的总正常值; S4）发出肾脏的至少一个损伤特征值（2）。

    TREATMENT STRUCTURE AND METHODS OF USE
    195.
    发明申请
    TREATMENT STRUCTURE AND METHODS OF USE 审中-公开
    治疗结构与使用方法

    公开(公告)号：US20150173830A1

    公开(公告)日：2015-06-25

    申请号：US14581638

    申请日：2014-12-23

    Applicant: Eric JOHNSON ,  Jeremy STIGALL

    Inventor： Eric JOHNSON ,  Jeremy STIGALL

    IPC: A61B18/14 ,  A61B5/06 ,  A61F7/12 ,  A61B8/08 ,  A61F7/00 ,  A61B18/02

    CPC classification number: A61B18/1492 ,  A61B5/061 ,  A61B5/201 ,  A61B5/4005 ,  A61B5/4035 ,  A61B8/0841 ,  A61B8/12 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00982 ,  A61B2018/0212 ,  A61B2018/1435

    Abstract: Catheter based ablation devices, systems, and methods for achieving intraluminal and/or transluminal neuromodulation, stimulation or ablation by intraluminal access are disclosed herein. One aspect of the present application, for example, is directed to devices, systems, and methods that incorporate a spiral support frame treatment device on an elongate shaft or as a temporary or permanently implanted therapy device. The elongated shaft is sized and configured to deliver a spiral treatment device to a treatment position via an intravascular path. Intraluminal and transluminal neuromodulation, stimulation or ablation or other therapeutic outcomes may be achieved via energy delivered via the spiral element. One therapy includes modulation of neural fibers that contribute to or alter vascular structures that feed or perfuse the neural fibers.

    Abstract translation: 本文公开了基于导管的消融装置，系统和用于实现管腔内和/或经腔神经调节，通过管腔内通路的刺激或消融的方法。 例如，本申请的一个方面涉及在细长轴上或作为临时或永久植入的治疗装置中并入螺旋支撑框架治疗装置的装置，系统和方法。 细长轴的尺寸和构造被设计成经由血管内路径将螺旋治疗装置输送到治疗位置。 腔内和腔内神经调节，刺激或消融或其他治疗结果可以通过经由螺旋元件递送的能量来实现。 一种疗法包括调节神经纤维，其有助于或改变供给或灌注神经纤维的血管结构。

    INTRAVASCULAR CATHETER WITH PERI-VASCULAR NERVE ACTIVITY SENSORS
    196.
    发明申请
    INTRAVASCULAR CATHETER WITH PERI-VASCULAR NERVE ACTIVITY SENSORS 有权
    带血管神经活动传感器的血管内导管

    公开(公告)号：US20150119674A1

    公开(公告)日：2015-04-30

    申请号：US14063907

    申请日：2013-10-25

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell ,  Vartan Ghazarossian ,  Steven Almany

    IPC: A61B5/04 ,  A61B18/14 ,  A61B5/00

    CPC classification number: A61B5/04001 ,  A61B5/201 ,  A61B5/4035 ,  A61B5/6848 ,  A61B5/6852 ,  A61B17/320068 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/00214 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00839 ,  A61B2018/0212 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2090/3966 ,  A61M2025/0095

    Abstract: An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. The addition of an injection lumen at the proximal end of the catheter and openings in the needles adds the functionality of ablative fluid injection into the perivascular space for an integrated nerve sending and ablation capability.

    Abstract translation: 用于周围血管神经活动感测或测量的血管内导管包括通过支撑的导管（针引导元件）前进的多个针，其以围绕中心轴线的开口端膨胀，以接触肾动脉或其他血管的壁的内表面 人体允许针通过血管壁进入血管周围空间。 该系统还可以包括限制和/或调整针的穿透深度的装置。 导管还包括向引导管提供径向和横向支撑的结构，使得引导管均匀地打开并且当尖锐的针被推进以穿透到血管壁时，它们保持其抵靠血管壁的内表面的位置。 在导管的近端添加注射腔和针中的开口，将烧蚀液注入到血管周围空间中的功能可用于整合的神经发生和消融能力。

    Methods and Systems for Processing Test Results Based on Patient-Specific Data and Reference Data
    199.
    发明申请
    Methods and Systems for Processing Test Results Based on Patient-Specific Data and Reference Data 审中-公开
    基于患者特定数据和参考数据处理测试结果的方法和系统

    公开(公告)号：US20150025808A1

    公开(公告)日：2015-01-22

    申请号：US13944460

    申请日：2013-07-17

    Applicant: IDEXX Laboratories, Inc.

    Inventor： Jason Aguiar

    IPC: G06F19/00

    CPC classification number: G16H15/00 ,  A61B5/201 ,  A61B5/7275 ,  A61B2503/40 ,  G16H10/60 ,  G16H50/20 ,  G16H50/70

    Abstract: Methods and systems for processing test results based on patient-specific data and reference data are provided. An example method includes processing a result of a diagnostic test performed on a patient based on reference data that is based on testing of a group of patients. The method also includes processing the result based on patient-specific data that includes previous test results of the diagnostic test previously performed on the patient, and providing an indication indicative of an abnormal test result based on the result being in a normal range of the reference data and having a variance from the patient-specific data of a threshold amount. In another example, a method includes providing an indication indicative of a normal test result based on the result being outside a normal range of the reference data and being between an upper limit and a lower limit of the patient-specific data.

    Abstract translation: 提供了基于患者特定数据和参考数据处理测试结果的方法和系统。 一种示例性方法包括基于基于一组患者的测试的参考数据来处理对患者进行的诊断测试的结果。 该方法还包括基于患者特定数据处理结果，所述数据包括先前对患者执行的诊断测试的先前测试结果，并且基于在参考的正常范围内的结果提供指示异常测试结果的指示 数据并且具有与阈值量的患者特定数据的差异。 在另一示例中，一种方法包括基于结果在参考数据的正常范围之外提供指示正常测试结果的指示，并且处于患者特定数据的上限和下限之间。

    DIAGNOSTIC METHODS AND SYSTEMS BASED ON URINE ANALYSIS
    200.
    发明申请
    DIAGNOSTIC METHODS AND SYSTEMS BASED ON URINE ANALYSIS 审中-公开
    基于尿素分析的诊断方法和系统

    公开(公告)号：US20140316219A1

    公开(公告)日：2014-10-23

    申请号：US14319585

    申请日：2014-06-30

    Applicant: FlowSense Ltd.

    Inventor： Ilan Paz ,  Martin Clive Henry Jackson ,  Stanley Chimes

    IPC: A61B5/20 ,  A61B5/1495 ,  A61B5/1473 ,  A61B5/00 ,  A61B5/145

    CPC classification number: A61B5/201 ,  A61B5/14507 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/208 ,  A61B5/412 ,  A61B5/486 ,  A61B5/6852 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B10/007 ,  G01N33/493

    Abstract: A method for diagnosing a body malfunction is provided. At least one change in urinary parameter values, being indicative of the body malfunction, is monitored and detected. A volumetric urinary output of kidneys is monitored using a urine flow monitoring apparatus having a low flow metering device. It is determined whether a change exists in at least one of a volume value of the volumetric urinary output, and a trend of the corresponding urinary parameter value during a predetermined period. Signals are received from a plurality of electrodes, representing the urinary parameter values. The body malfunction is detected based on the determination of the change in at least one of the volume value and the trend.

    Abstract translation: 提供了诊断身体故障的方法。 监测和检测尿指参数值中至少一个变化，表示身体故障。 使用具有低流量计量装置的尿流监测装置监测肾的体积尿量。 确定体积尿输出的体积值中的至少一个是否存在变化，以及在预定时段期间相应的尿参数值的趋势。 从多个电极接收信号，表示尿参数值。 基于体积值和趋势中的至少一个的变化的确定来检测身体故障。

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