公开(公告)号：US20080161697A1

公开(公告)日：2008-07-03

申请号：US11369221

申请日：2006-03-06

Applicant: Britton Chance

Inventor： Britton Chance

IPC: A61B6/00

CPC classification number: G01N21/6456 ,  A61B5/0073 ,  A61B5/0091 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/14553 ,  A61B5/4312 ,  A61B5/7239 ,  A61B2562/0233 ,  A61B2562/0242 ,  A61B2562/043 ,  G01N21/3151 ,  G01N21/47 ,  G01N21/4795 ,  G01N21/49 ,  G01N21/6486 ,  G01N2021/1789 ,  G01N2021/3181 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N2201/0696

Abstract: A spectroscopic method and system for examination of biological tissue includes multiple input ports optically connected to at least one light source, multiple detection ports optically connected to at least one detector, a radiation pattern controller coupled to the light source and detector, and a processor. The multiple input ports are arranged to introduce light at input locations into biological tissue and the multiple detection ports are arranged to collect light from detection locations of the biological tissue. The radiation pattern controller is constructed to control patterns of light introduced from the multiple input ports and constructed to control detection of light migrating to the multiple detection ports. The processor is operatively connected to the radiation pattern controller and connected to receive detector signals from the detector, and is constructed to examine a tissue region based on the introduced and detected light patterns.

Abstract translation: 用于检查生物组织的光谱方法和系统包括与至少一个光源光学连接的多个输入端口，与至少一个检测器光学连接的多个检测端口，耦合到光源和检测器的辐射图案控制器以及处理器。 多个输入端口被布置成将输入位置处的光引入生物组织，并且多个检测端口被布置成从生物组织的检测位置收集光。 辐射图形控制器被构造为控制从多个输入端口引入的光的图案，并被构造成控制对多个检测端口迁移的光的检测。 处理器可操作地连接到辐射图案控制器并被连接以接收来自检测器的检测器信号，并且被构造成基于引入和检测到的光图案来检查组织区域。

公开(公告)号：US07141212B2

公开(公告)日：2006-11-28

申请号：US08338141

申请日：1994-11-09

Applicant: Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

Inventor： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

IPC: G01N21/00

CPC classification number: G01N21/8483 ,  B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

Abstract: A method of “reading” the result of an assay effected by concentrating a detectable material in a comparatively small zone of a carrier in the form of a strip, sheet or layer through the thickness of which electromagnetic radiation such as visible light is transmissible, wherein at least a portion of one face or the carrier is exposed to incident electromagnetic radiation which is substantially uniform across the entire portion, the portion including the small zone, and electromagnetic radiation emerging from the opposite face of the carrier is measured to determine the assay result. Preferably the radiation is diffuse light.

Abstract translation: 通过将可检测材料集中在带状，片状或层状形式的载体的相对小的区域中，通过将电磁辐射如可见光透射的厚度集中在其中，“读取”测定结果的方法，其中 一个面或载体的至少一部分暴露于跨越整个部分基本均匀的入射电磁辐射，测量包括小区域的部分和从载体的相对面出射的电磁辐射以确定测定结果 。 优选地，辐射是漫射光。

公开(公告)号：US07006923B1

公开(公告)日：2006-02-28

申请号：US10849451

申请日：2004-05-19

Applicant: Stuart H. Rubin

Inventor： Stuart H. Rubin

IPC: G01N21/85

CPC classification number: G01N15/1463 ,  G01N21/05 ,  G01N21/33 ,  G01N21/94 ,  G01N2001/2223 ,  G01N2015/0088 ,  G01N2021/1793 ,  G01N2201/0696 ,  G01N2201/1296

Abstract: A distributed biohazard surveillance system including a plurality of robust miniaturized remote monitoring stations for the detection, localized analysis and reporting of a broad range of biohazards. The remote monitoring station may be adapted to identify many different biological particles and is not limited to particular predetermined biohazard profiles. It is centrally and dynamically reconfigurable and can be adapted to operate unattended in a remote location. The distributed system may be used to locate and report unsuspected sources of biohazards and to monitor the localized effects in real-time cooperation with a centralized data processing facility.

Abstract translation: 分布式生物危害监测系统，包括多个稳健的小型化远程监测站，用于检测，局部分析和报告广泛的生物危害。 远程监测站可以适于识别许多不同的生物颗粒，并且不限于特定的预定生物危害谱。 它是集中和动态可重新配置的，可以适应在远程位置无人值守操作。 分布式系统可用于定位和报告未预期的生物危害源，并监测与集中式数据处理设施实时协作的局部效应。

公开(公告)号：US06995360B2

公开(公告)日：2006-02-07

申请号：US10444586

申请日：2003-05-23

Applicant: Timothy Gareth John Jones ,  Boris Matveev ,  Vladimir Vaynshteyn ,  Christian Besson ,  Oliver C. Mullins ,  Li Jiang

Inventor： Timothy Gareth John Jones ,  Boris Matveev ,  Vladimir Vaynshteyn ,  Christian Besson ,  Oliver C. Mullins ,  Li Jiang

IPC: G01V5/08

CPC classification number: E21B49/08 ,  B08B7/028 ,  G01N21/0303 ,  G01N21/3504 ,  G01N21/552 ,  G01N2021/154 ,  G01N2021/3181 ,  G01N2201/0624 ,  G01N2201/0696

Abstract: A method of monitoring gas in a downhole environment is discussed which provides downhole a mid-infrared light emitting diode, operates the diode to transmit respective infrared signals on a first optical path extending from the diode through a downhole gas sample and a second optical path extending from the diode through a reference gas sample, detects the transmitted infrared signals, and determines the concentration of a component of the downhole gas sample from the detected signals.

Abstract translation: 讨论了一种在井下环境中监测气体的方法，其提供了一种中央红外发光二极管的井下，操作二极管以在从二极管延伸穿过井下气体样品的第一光路和第二光路延伸的第二光路上传输相应的红外信号 从二极管通过参考气体样品检测发射的红外信号，并根据检测到的信号确定井下气体样品的分量浓度。

公开(公告)号：US20050134846A1

公开(公告)日：2005-06-23

申请号：US11011095

申请日：2004-12-15

Applicant: Albert Kreh ,  Henning Backhauss

Inventor： Albert Kreh ,  Henning Backhauss

IPC: G01N21/47 ,  G01N21/95 ,  G01N21/00

CPC classification number: G01N21/9501 ,  G01N21/4788 ,  G01N2201/0696

Abstract: The apparatus encompasses at least one stroboscopic incident-light illumination device for emitting a pulsed illuminating light beam onto a surface of the wafer and for illuminating a region on the surface of the wafer; and having at least one image acquisition device for acquiring an image of the respectively illuminated region on the surface of the wafer. The apparatus is characterized, according to the present invention, in that by at least one photodetection device for sensing light of the respective illuminating light beam, and a control device for controlling an image acquisition operation on the basis of the light sensed by the photodetection device, are provided. Intensity fluctuations of the light flashes of the incident-light illumination device are compensated for either by normalizing image data of the illuminated region or by controlling the duration of the light flashes.

Abstract translation: 该装置包括至少一个频闪入射光照明装置，用于将脉冲照明光束发射到晶片的表面上并用于照射晶片表面上的区域; 并且具有用于获取晶片表面上的分别照明区域的图像的至少一个图像采集装置。 该装置的特征在于，根据本发明，通过至少一个用于感测各个照明光束的光的光检测装置和用于基于由光检测装置感测的光来控制图像获取操作的控制装置 ，提供。 通过归一化照明区域的图像数据或通过控制闪光的持续时间来补偿入射光照明装置的闪光的强度波动。

公开(公告)号：USRE37713E1

公开(公告)日：2002-05-28

申请号：US29107620

申请日：1999-09-03

Applicant: Michael Thomas Pearson ,  Kishen Gohil

Inventor： Michael Thomas Pearson ,  Kishen Gohil

IPC: B01L3/00 ,  G01N21/86 ,  G01N37/00

CPC classification number: G01N21/8483 ,  B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

公开(公告)号：US06324298B1

公开(公告)日：2001-11-27

申请号：US09352564

申请日：1999-07-13

Applicant: Jeffrey O'Dell ,  Mark Harless ,  Thomas Verburgt

Inventor： Jeffrey O'Dell ,  Mark Harless ,  Thomas Verburgt

IPC: G06K962

CPC classification number: G01N21/9501 ,  G01N21/8803 ,  G01N21/8806 ,  G01N2021/8838 ,  G01N2201/06113 ,  G01N2201/0696 ,  G01N2201/0697 ,  G01N2201/12 ,  G06T7/0004 ,  G06T2207/30148 ,  H01L21/67242 ,  H01L21/67271 ,  H01L21/67288 ,  H01L22/12 ,  H01L2924/0002 ,  H04N5/2256 ,  H01L2924/00

Abstract: An automated defect inspection system has been invented and is used on patterned wafers, whole wafers, broken wafers, partial wafers, sawn wafers such as on film frames, JEDEC trays, Auer boats, die in gel or waffle packs, MCMs, etc. and is specifically intended and designed for second optical wafer inspection for such defects as metalization defects (such as scratches, voids, corrosion, and bridging), diffusion defects, passivation layer defects, scribing defects, glassivation defects, chips and cracks from sawing, solder bump defects, and bond pad area defects.

Abstract translation: 已经发明了一种自动化缺陷检测系统，用于图案化的晶片，整个晶片，破碎的晶片，部分晶片，锯片，如胶片框架，JEDEC托盘，Auer船，凝胶或华夫饼包，MCM等，以及 专门用于第二光学晶片检查，用于诸如金属化缺陷（例如划痕，空隙，腐蚀和桥接），扩散缺陷，钝化层缺陷，划线缺陷，玻璃化缺陷，切屑和锯切裂纹等缺陷，焊料凸块 缺陷和焊盘区域缺陷。

公开(公告)号：US06235241B1

公开(公告)日：2001-05-22

申请号：US09078501

申请日：1998-05-14

Applicant: Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

Inventor： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

IPC: G01N2100

CPC classification number: B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N21/8483 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

Abstract: An assay result reader, for use in conjunction with an assay device comprising a porous liquid-permeable carrier in the form of a strip or sheet through the thickness of which electromagnetic radiation is transmissible, the carrier including a detection zone in which an assay result is revealed by specific binding of a detectable material directly or indirectly to a binding agent immobilized in the detection zone, detection of the detectable material being effected by determining the extent to which electromagnetic radiation transmitted through the thickness of said carrier is attenuated by the presence of the detectable material bound in the detection zone.

Abstract translation: 测定结果读取器，用于与测定装置结合使用，所述测定装置包括通过电磁辐射可传播的厚度的带状或片状形式的多孔液体可渗透载体，所述载体包括检测区域，其中测定结果为 通过将可检测材料直接或间接地特异性结合到固定在检测区中的结合剂来显示，可检测材料的检测是通过确定通过所述载体的厚度传输的电磁辐射的程度通过存在 在检测区域中结合的可检测材料。

公开(公告)号：US6134460A

公开(公告)日：2000-10-17

申请号：US731443

申请日：1996-10-15

Applicant: Britton Chance

Inventor： Britton Chance

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/1495 ,  A61B10/00 ,  G01N21/27 ,  G01N21/31 ,  G01N21/47 ,  G01N21/49 ,  G01N21/64

CPC classification number: A61B5/14551 ,  A61B5/14552 ,  A61B5/14553 ,  A61B5/1459 ,  A61B5/6828 ,  G01N21/3151 ,  G01N21/4795 ,  G01N21/49 ,  A61B2562/0233 ,  A61B2562/0242 ,  A61B2562/043 ,  G01N2021/1789 ,  G01N2021/3181 ,  G01N21/47 ,  G01N2201/0696

Abstract: The present invention provides in various embodiments novel, wearable systems for determining the metabolic condition of an aerobically stressed portion of tissue such as the muscle tissue of an exercising person. Generally, the systems comprise lightweight rugged detectors, worn adjacent the tissue being monitored. The system of the present invention thus minimizes any performance impairment. In preferred systems a wearable power pack and a wearable display means are provided for displaying information indicative of the aerobic metabolic condition of the region being monitored. In a preferred embodiment intended for use while running or engaged in similar athletic activities, the display is worn on the wrist and displays information from a leg-mounted detector. In another embodiment, intended to provide information to coaches, a telemetry system is employed to transmit a signal carrying the data from the detector to a remote location, for processing and display. Various other embodiments and applications are also included.

Abstract translation: 本发明在各种实施方案中提供了用于确定诸如锻炼者的肌肉组织的组织有氧应激部分的代谢状况的新型可穿戴系统。 通常，系统包括邻近被监测的组织的轻质坚固检测器。 因此，本发明的系统使任何性能损害最小化。 在优选的系统中，提供了一种可戴式电源组件和一种穿戴式显示装置，用于显示指示所监视区域的有氧代谢状态的信息。 在旨在用于运行或参与类似运动活动的优选实施例中，显示器佩戴在手腕上并且显示来自腿部安装的检测器的信息。 在另一个实施例中，为了向教练提供信息，采用遥测系统将携带数据的信号从检测器传送到远程位置，以进行处理和显示。 还包括各种其他实施例和应用。

公开(公告)号：US06058324A

公开(公告)日：2000-05-02

申请号：US170833

申请日：1998-10-13

Applicant: Britton Chance

Inventor： Britton Chance

IPC: A61B5/00 ,  G01N21/47

CPC classification number: A61B5/14553 ,  A61B5/0073 ,  A61B5/0091 ,  A61B5/1455 ,  A61B5/4312 ,  A61B5/6814 ,  G01N21/3151 ,  G01N21/4795 ,  G01N21/49 ,  G01N21/6456 ,  A61B2562/0233 ,  A61B2562/0242 ,  A61B2562/043 ,  A61B2562/146 ,  A61B5/14551 ,  G01N2021/1789 ,  G01N2021/3181 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N21/47 ,  G01N2201/0696

Abstract: Optical methods and systems for in vivo, non-invasive examination of biological tissue include at least one light source constructed to emit light of a visible or infra-red wavelength for introduction into an examined tissue volume from at least one input port, and at least one detector constructed to detect light of the visible or infra-red wavelength that has migrated in the examined tissue volume from at least one input port to at least one detection port. The optical systems also include an optical array, a radiation controller, and a processor. The optical array includes the input and detection ports located in a selected geometrical pattern providing several average photon migration pathlengths in the examined tissue volume. Each arrangement of least one input port and at least one detection port provides one of the average pathlengths, wherein the average pathlength is characteristic of the tissue between one input port and one detection port. The radiation controller is constructed to sequentially control light emitted from the at least one input port and constructed to control detection of light of the introduced wavelength to define a null plane in the tissue volume for two of the arrangements of the input and detection ports. The processor is operatively connected to the radiation controller and is constructed to examine the biological tissue based on data corresponding to the introduced and detected light for at least two of the average pathlengths and the defined location of the null plane.

Abstract translation: 用于生物组织的体内非侵入性检查的光学方法和系统包括构造成发射可见光或红外波长的光的至少一个光源，用于从至少一个输入端口引入检查的组织体积，并且至少 一个检测器，其被构造成检测已经在检查的组织体积中从至少一个输入端口迁移到至少一个检测端口的可见或红外波长的光。 光学系统还包括光学阵列，辐射控制器和处理器。 光学阵列包括位于所选择的几何图案中的输入和检测端口，提供检查的组织体积中的几个平均光子迁移路径长度。 至少一个输入端口和至少一个检测端口的每个布置提供平均路径长度之一，其中平均路径长度是一个输入端口和一个检测端口之间的组织的特征。 辐射控制器被构造成顺序地控制从至少一个输入端口发射的光，并被构造成控制引入波长的光的检测，以在输入和检测端口的两个布置中的组织体积中定义零平面。 处理器可操作地连接到辐射控制器，并被构造成基于对于平均路径长度和零平面的限定位置中的至少两个的引入和检测到的光的数据来检查生物组织。