Mode matching method for absorption spectroscopy systems

    公开(公告)号:US11441944B2

    公开(公告)日:2022-09-13

    申请号:US16734078

    申请日:2020-01-03

    Applicant: Li-Cor, Inc.

    Inventor: Ahmed Bouzid

    Abstract: Systems and methods for controlling optical feedback in an optical system. A resonant optical cavity includes at least two cavity mirrors, one of which is a cavity coupling mirror, and has a plurality of optical resonance cavity modes. A radiation source emits a beam of continuous wave radiation and is capable of being scanned whereby a mean optical frequency of the continuous wave radiation beam is adjustable over a range of frequencies, wherein the radiation source is responsive to optical feedback radiation emerging from the cavity, and wherein the mode matching optics couples the beam of continuous wave radiation to the cavity via the cavity coupling mirror. The radiation source and the mode matching optics are aligned so that a mode fill ratio is reduced relative to a maximum mode fill ratio, wherein the laser beam is coupled with a fundamental cavity mode.

    Spectroscopic biological material characterization

    公开(公告)号:US11428638B2

    公开(公告)日:2022-08-30

    申请号:US16961675

    申请日:2019-01-11

    Abstract: Systems and methods for characterizing biological specimens, which may involve identifying a cell type or state corresponding to a disease or health condition of a subject. A biological specimen is subjected to electromagnetic radiation for spectroscopic analysis such as Surface Enhanced Raman Spectroscopy (SERS) to determine the relative abundance of proteins or amino acids in the cells, which is used in a comparison to previously stored relative abundance data of a database to automatically identifies at least one of cell type and/or cell state of the cells (or the disease/health state of the subject with the disease state including the possibility of virus infection, or drug susceptibility of a subject to bacteria or fungus). The method may also be employed with biological entities or cellular structures such as exosomes and even protein or nucleic acid fragments to determine disease states or health states of the subject.

    Light emitting structure, photo-acoustic spectroscopy sensing device, method

    公开(公告)号:US11428573B2

    公开(公告)日:2022-08-30

    申请号:US17112144

    申请日:2020-12-04

    Abstract: A light emitting structure for a photo-acoustic spectroscopy sensing device for sensing a target gas comprises a light source configured for emitting light of an input wavelength. The light emitting structure further comprises a conversion structure that is configured for absorbing light of the input wavelength, and that is further configured for emitting light of an output wavelength. The output wavelength of the conversion structure is adapted to an absorption wavelength of the target gas. The conversion structure comprises an output conversion layer that comprises a plurality of nanoparticles. The nanoparticles of the output conversion layer are configured for emitting light of the output wavelength.

    Biopsy device for coherent Raman imaging

    公开(公告)号:US11419590B2

    公开(公告)日:2022-08-23

    申请号:US16994327

    申请日:2020-08-14

    Abstract: Devices and systems for analyzing biological samples are provided. Devices include a hollow body extending from a first end to a second end. The body defines a sample collecting portion. A first opening at the first end of the body is operable to receive a source of negative pressure and a second opening at the second end of the body is operable to receive a biological sample. The body also includes an optically transparent region disposed in a region corresponding to the sample collecting portion, the optically transparent region being configured to transmit electromagnetic radiation therethrough from an imaging device capable of imaging the biological sample when disposed in the sample collecting portion.

    REFRACTORY ANCHOR DEVICE AND SYSTEM
    267.
    发明申请

    公开(公告)号:US20220260783A1

    公开(公告)日:2022-08-18

    申请号:US17735696

    申请日:2022-05-03

    Abstract: Refractory anchoring devices include a main body and a mounting feature for mounting to a thermal vessel. The main body has the shape of two end-to-end Y's forming a central segment, two branch segments extending from each end of the central segment, and an extension segment extending from each of the four branch segments, to collectively form four unenclosed cell openings that are each semi-hexagonal in shape. Some embodiments include four reinforcement segments with each one extending into a respective cell opening, four voids with each one extending through respective adjacent branch and extension segments, an underbody gap formed under the central segment for refractory interlinking between cell openings, and/or a single stud-welding stud for the mounting feature. Refractory anchoring systems and methods include an array of the refractory anchoring devices arranged and mounted so that the unenclosed semi-hexagonal cell openings of adjacent anchoring devices cooperatively form substantially hexagonal cells.

    DETECTION OF LIGHT SOURCE DISTORTION IN AN IMAGING SYSTEM

    公开(公告)号:US20220244103A1

    公开(公告)日:2022-08-04

    申请号:US17649364

    申请日:2022-01-30

    Applicant: Spectricity

    Abstract: An imaging system includes a plurality of optical sensors arranged on an integrated circuit in an array with a plurality of rows and a plurality of columns. The system includes an interface communicating with the plurality of optical sensors, memory storing operational instructions and processing circuitry configured to sample an image using the plurality of optical sensors in a first mode and sample at least a portion of the image sequentially on a row-by-row basis at a predetermined sampling rate in a second mode to produce row by row sample outputs. The processing circuitry is further configured to initiate sampling at least some rows of the plurality of rows of optical sensors using different time stamps.

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