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公开(公告)号:US20150276613A1
公开(公告)日:2015-10-01
申请号:US14437279
申请日:2013-10-24
Applicant: CHARM SCIENCES, INC.
Inventor: Robert J. Markovsky
CPC classification number: G01N21/8483 , G01N21/75 , G01N30/86 , G01N30/95 , G01N2021/752 , G01N2021/754 , G01N2021/755
Abstract: Detecting a definitive presence or absence of an analyte from a borderline test is shown and described. In one embodiment, a method of generating a definitive test result includes continuously incubating the assay concurrently with continuously reading a diagnostic test on the assay. In particular examples, reading the diagnostic test on the assay includes performing a one minute diagnostic reading. Typically, when a borderline test result is detected, further development of the assay is performed. In most examples, detecting a definitive presence or absence test result deactivates the testing sequence.
Abstract translation: 显示和描述了从边界线测试中检测到分析物的确定存在或不存在。 在一个实施方案中,产生确定性测试结果的方法包括连续地孵育测定同时连续读取测定的诊断测试。 在具体实例中,阅读测定的诊断测试包括执行一分钟诊断阅读。 通常,当检测到边界测试结果时,进行测定的进一步开发。 在大多数示例中,检测确定的存在或不存在测试结果将使测试序列无效。
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公开(公告)号:US20140334980A1
公开(公告)日:2014-11-13
申请号:US14207896
申请日:2014-03-13
Applicant: Charm Sciences, Inc.
Inventor: Paul E. Graham , Robert J. Markovsky
CPC classification number: G01N33/58 , G01N21/8483 , G01N33/54386 , G01N35/00722 , G01N2015/0065 , G01N2035/00108 , G01N2035/00772 , G01N2035/00851
Abstract: Analyte detection systems and devices are provided. In one embodiment, a sensor initially reviews an assay, for instance a test strip, to designate a particular testing sequence. The sensor may calibrate the unit and then identify the particular testing sequence by identifying a color indicator on the test strip. The result is systems and methods to improve the detection of the presence and/or absence of at least one analyte in a sample.
Abstract translation: 提供了分析物检测系统和设备。 在一个实施例中,传感器首先检查测定,例如测试条,以指定特定测试序列。 传感器可以校准单位,然后通过识别测试条上的颜色指示器来识别特定的测试顺序。 结果是改进对样品中至少一种分析物的存在和/或不存在的检测的系统和方法。
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公开(公告)号:US20250116600A1
公开(公告)日:2025-04-10
申请号:US18834744
申请日:2023-02-03
Applicant: Charm Sciences, Inc.
Inventor: Paul E. Graham , Robert J. Markovsky
Abstract: Analyte testing devices, assemblies, methods, operations, and systems are shown and described. In one embodiment, an apparatus to generate a test result from an assay, when contacted with a sample, includes a non-planar optics module, an imaging device, and a direct, dynamically-controlled lighting assembly. The assembly may include an aperture carrier heat block having a plurality of optical windows and enhancing manipulation of an assay about the assembly.
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公开(公告)号:US20220291133A1
公开(公告)日:2022-09-15
申请号:US17639601
申请日:2020-09-03
Applicant: Charm Sciences Inc.
Inventor: Paul Graham , Robert J Markovsky
Abstract: Analyte testing devices, assemblies, methods, operations, and systems are shown and described. In one embodiment, an apparatus to generate a test result from an assay when contacted with a sample includes a non-planar optics module to align the assay in an offset testing position. A modular interface assembly may support a motherboard and at least one non-planar optics module.
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公开(公告)号:US20220236151A1
公开(公告)日:2022-07-28
申请号:US17588658
申请日:2022-01-31
Applicant: Charm Sciences, Inc.
Inventor: John Jabour , Steven J. Saul , Mark E. Tess
IPC: G01N1/34 , G01N33/543 , G01N33/569 , G01N1/40 , G01N33/10
Abstract: A method for extracting a mycotoxin, when present, from a sample. Compositions and methods include the use of high ionic strength compositions including compositions that include many amine and/or carboxyl groups such as protein based, amino acid based and polyethylene glycol based composition.
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公开(公告)号:US11119102B1
公开(公告)日:2021-09-14
申请号:US15434399
申请日:2017-02-16
Applicant: Charm Sciences, Inc.
Inventor: Robert J Markovsky , Cody Thiboult
IPC: G01N33/558 , G01N33/543 , G01N33/58 , G01N33/553
Abstract: Test strip devices, assemblies, systems, and methods for the analysis of a sample are shown and described. In one embodiment, a test strip includes a nitrocellulose membrane, a filtration conjugate pad with a fibrous labeled receptor bottom side, and an overlay tape enclosing the nitrocellulose membrane and a portion of the filtration conjugate pad. An assembly may include a delivery device for delivering sample to the test strip.
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公开(公告)号:US11073520B1
公开(公告)日:2021-07-27
申请号:US16369524
申请日:2019-03-29
Applicant: Charm Sciences, Inc.
Inventor: Robert J. Markovsky , David W. Douglas
IPC: G01N33/558 , G01N33/569
Abstract: Embodiments described herein include detecting an analyte in a low pH sample. Some embodiments include detection of multiple analytes in a sample utilizing a plurality of analyte binders and a control zone containing multiple control zone capture agents. In some embodiments, the multiple control zone capture agents capture a plurality of binders within one control zone.
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公开(公告)号:US11009446B1
公开(公告)日:2021-05-18
申请号:US16666547
申请日:2019-10-29
Applicant: Charm Sciences, Inc.
Inventor: Richard T. Skiffington , Robert S. Salter , Robert J. Markovsky , Stanley E. Charm , Paul E. Graham , Jovo Djuragic
IPC: G06K9/00 , G01N15/14 , C12Q1/02 , G06T7/00 , G06T7/11 , G06T5/20 , G06T5/40 , G08B21/18 , G01N15/00 , G01N15/10
Abstract: Reader observation and monitoring of the imaging of biological development is shown and described. In one embodiment, a method for monitoring biological growth includes identifying an alert from comparing a background value identified on a plate to a non-background value identified on a plate. In particular examples, a pre-filter, threshold, and histogram analysis identifies an alert count.
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公开(公告)号:US20200217799A1
公开(公告)日:2020-07-09
申请号:US16825357
申请日:2020-03-20
Applicant: Charm Sciences, Inc.
Inventor: Robert J. Markovsky , Stanley E. Charm , Paul E. Graham , Richard T. Skiffington
Abstract: System, apparatus, and assemblies for the detection of at least one analyte in a sample are shown and described. The system may be an onboard vehicle system to generate an antibiotic test result from an antibiotic analyte assay.
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公开(公告)号:US20200080044A1
公开(公告)日:2020-03-12
申请号:US16173130
申请日:2017-04-28
Applicant: Charm Sciences, Inc.
Inventor: Robert J. Markovsky , Paul E. Graham , Richard T. Skiffington , Scott Sutherland
Abstract: Reader and plate methods, operations, and systems for imaging/counting biological development on plates are shown and described. One embodiment includes calibrating a plate reader. Calibration may be triggered by detecting a quality control event or the like. The calibration process may include receiving a low and/or high calibrator, counting objects on the calibrator(s), and comparing objects on the calibrator(s) to a predetermined limit. The result is an improved plate reader for observing biological growth, when present, on a growth plate.
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