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公开(公告)号：US20210215615A1
公开(公告)日：2021-07-15
申请号：US17215004
申请日：2021-03-29
Applicant: Charm Sciences, Inc.
Inventor： Robert J. Markovsky , Stanley E. Charm , Paul E. Graham , Richard T. Skiffington
Abstract: Apparatus and assemblies for the detection of at least one analyte in a sample are shown and described. In one embodiment, the assembly generates a test result from an assay and includes an integrated reader and incubator, wherein the incubator incubates the assay as the reader generates the test result. The reader typically has an optical detector aligned with a light source for detecting a plurality of transmission of light on the assay. The result is systems and methods to improve the detection of the presence and/or absence of at least one analyte in a sample.
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公开(公告)号：US11002683B2
公开(公告)日：2021-05-11
申请号：US16278935
申请日：2019-02-19
Applicant: Charm Sciences, Inc.
Inventor： Robert J. Markovsky , Stanley E. Charm , Paul E. Graham , Richard T. Skiffington
Abstract: Apparatus and assemblies for the detection of at least one analyte in a sample are shown and described. In one embodiment, the assembly generates a test result from an assay and includes an integrated reader and incubator, wherein the incubator incubates the assay as the reader generates the test result. The reader typically has an optical detector aligned with a light source for detecting a plurality of transmission of light on the assay. The result is systems and methods to improve the detection of the presence and/or absence of at least one analyte in a sample.
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公开(公告)号：US09976962B2
公开(公告)日：2018-05-22
申请号：US15835979
申请日：2017-12-08
Applicant: Charm Sciences, Inc.
Inventor： Robert J. Markovsky , Stanley E. Charm , Paul E. Graham , Richard T. Skiffington
CPC classification number: G01N21/75 , G01N21/78 , G01N21/8483 , G01N2201/0627
Abstract: Apparatus and assemblies for the detection of at least one analyte in a sample are shown and described. In one embodiment, the assembly generates a test result from an assay and includes an integrated reader and incubator, wherein the incubator incubates the assay as the reader generates the test result. The reader typically has an optical detector aligned with a light source for detecting a plurality of transmission of light on the assay. The result is systems and methods to improve the detection of the presence and/or absence of at least one analyte in a sample.
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公开(公告)号：US10274489B2
公开(公告)日：2019-04-30
申请号：US14823321
申请日：2014-02-11
Applicant: Charm Sciences, Inc.
Inventor： Robert J. Markovsky , Richard T. Skiffington , Stanley E. Charm
IPC: G01N21/84 , B01L3/00 , G01N33/558 , G01N33/543
Abstract: Assessing test results development during assay analysis is shown and described. In one embodiment, an apparatus generates an assessment of diagnostic test development from an assay. The apparatus may include an optical detector aligned in an optical path with the assay. Further, the optical detector may perform continuous image detection of the assay to generate an assessment testing development. In some examples, the assessment is a graphical display of diagnostic development. In yet other embodiments, a method of assessing diagnostic test development may include signaling the optical detector to perform continuing image detection of the assay and generating an assessment of said diagnostic test development. The assessment may include graphing a reflectance detected on the assay on a display board.
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公开(公告)号：US20170184585A1
公开(公告)日：2017-06-29
申请号：US14823321
申请日：2014-02-11
Applicant: CHARM SCIENCES, INC.
Inventor： Robert J. Markovsky , Richard T. Skiffington , Stanley E. Charm
IPC: G01N33/558 , B01L3/00 , G01N33/543 , G01N21/84
CPC classification number: G01N33/558 , B01L3/5023 , B01L2300/023 , B01L2300/027 , B01L2300/0654 , B01L2300/069 , B01L2300/0825 , B01L2400/0406 , G01N21/8483 , G01N33/54366
Abstract: Assessing test results development during assay analysis is shown and described. In one embodiment, an apparatus generates an assessment of diagnostic test development from an assay. The apparatus may include an optical detector aligned in an optical path with the assay. Further, the optical detector may perform continuous image detection of the assay to generate an assessment testing development. In some examples, the assessment is a graphical display of diagnostic development. In yet other embodiments, a method of assessing diagnostic test development may include signaling the optical detector to perform continuing image detection of the assay and generating an assessment of said diagnostic test development. The assessment may include graphing a reflectance detected on the assay on a display board.
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Patent Agency Ranking
公开(公告)号：US20180238809A1
公开(公告)日：2018-08-23
申请号：US15958010
申请日：2018-04-20
Applicant: Charm Sciences, Inc.
Inventor： Robert J. Markovsky , Stanley E. Charm , Paul E. Graham , Richard T. Skiffington
CPC classification number: G01N21/75 , G01N21/78 , G01N21/8483 , G01N2201/0627
Abstract: Apparatus and assemblies for the detection of at least one analyte in a sample are shown and described. In one embodiment, the assembly generates a test result from an assay and includes an integrated reader and incubator, wherein the incubator incubates the assay as the reader generates the test result. The reader typically has an optical detector aligned with a light source for detecting a plurality of transmission of light on the assay. The result is systems and methods to improve the detection of the presence and/or absence of at least one analyte in a sample.
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公开(公告)号：US20150276613A1
公开(公告)日：2015-10-01
申请号：US14437279
申请日：2013-10-24
Applicant: CHARM SCIENCES, INC.
Inventor： Robert J. Markovsky
CPC classification number: G01N21/8483 , G01N21/75 , G01N30/86 , G01N30/95 , G01N2021/752 , G01N2021/754 , G01N2021/755
Abstract: Detecting a definitive presence or absence of an analyte from a borderline test is shown and described. In one embodiment, a method of generating a definitive test result includes continuously incubating the assay concurrently with continuously reading a diagnostic test on the assay. In particular examples, reading the diagnostic test on the assay includes performing a one minute diagnostic reading. Typically, when a borderline test result is detected, further development of the assay is performed. In most examples, detecting a definitive presence or absence test result deactivates the testing sequence.
Abstract translation: 显示和描述了从边界线测试中检测到分析物的确定存在或不存在。 在一个实施方案中，产生确定性测试结果的方法包括连续地孵育测定同时连续读取测定的诊断测试。 在具体实例中，阅读测定的诊断测试包括执行一分钟诊断阅读。 通常，当检测到边界测试结果时，进行测定的进一步开发。 在大多数示例中，检测确定的存在或不存在测试结果将使测试序列无效。
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公开(公告)号：US20140334980A1
公开(公告)日：2014-11-13
申请号：US14207896
申请日：2014-03-13
Applicant: Charm Sciences, Inc.
Inventor： Paul E. Graham , Robert J. Markovsky
CPC classification number: G01N33/58 , G01N21/8483 , G01N33/54386 , G01N35/00722 , G01N2015/0065 , G01N2035/00108 , G01N2035/00772 , G01N2035/00851
Abstract: Analyte detection systems and devices are provided. In one embodiment, a sensor initially reviews an assay, for instance a test strip, to designate a particular testing sequence. The sensor may calibrate the unit and then identify the particular testing sequence by identifying a color indicator on the test strip. The result is systems and methods to improve the detection of the presence and/or absence of at least one analyte in a sample.
Abstract translation: 提供了分析物检测系统和设备。 在一个实施例中，传感器首先检查测定，例如测试条，以指定特定测试序列。 传感器可以校准单位，然后通过识别测试条上的颜色指示器来识别特定的测试顺序。 结果是改进对样品中至少一种分析物的存在和/或不存在的检测的系统和方法。
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公开(公告)号：US20250116600A1
公开(公告)日：2025-04-10
申请号：US18834744
申请日：2023-02-03
Applicant: Charm Sciences, Inc.
Inventor： Paul E. Graham , Robert J. Markovsky
Abstract: Analyte testing devices, assemblies, methods, operations, and systems are shown and described. In one embodiment, an apparatus to generate a test result from an assay, when contacted with a sample, includes a non-planar optics module, an imaging device, and a direct, dynamically-controlled lighting assembly. The assembly may include an aperture carrier heat block having a plurality of optical windows and enhancing manipulation of an assay about the assembly.
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公开(公告)号：US11073520B1
公开(公告)日：2021-07-27
申请号：US16369524
申请日：2019-03-29
Applicant: Charm Sciences, Inc.
Inventor： Robert J. Markovsky , David W. Douglas
IPC: G01N33/558 , G01N33/569
Abstract: Embodiments described herein include detecting an analyte in a low pH sample. Some embodiments include detection of multiple analytes in a sample utilizing a plurality of analyte binders and a control zone containing multiple control zone capture agents. In some embodiments, the multiple control zone capture agents capture a plurality of binders within one control zone.
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